Visualizing Macrophage Polarization through Fluorescent mRNA Profiling.

Macrophages, known for their phenotypic plasticity, play a critical role in maintaining homeostasis and inflammation-related pathogenesis. Although identifying diverse macrophage phenotypes holds promise for enhancing diagnoses and treatments of diseases mediated by macrophages, existing methodologies for differentiating macrophages often lack precision. They are limited by the cumbersome procedures that require large-scale equipment, such as flow cytometry and transcriptomic analysis.

Design of Anti-Hund Organic Emitters Based on Heptazine.

Hund's rule, which is powerful in governing the first excited states of closed-shell organic materials, can hardly be violated to get inverted singlet-triplet gap (INVEST) molecules with negative singlet-triplet energy gaps (Δ), although INVEST materials have shown extraordinary photophysical properties and promising device performance especially in light-emitting diodes. Here, we propose a facile strategy to construct emissive INVEST molecules by introducing different types of substituents to heptazine in various modes, which can effectively tune the Δ to be negative with the enlarged oscillator strength () for the high fluorescence rate of the heptazine derivatives. Systematic computational studies show that the double substitution of electron-donating units with another nonconjugated substituent in hybrid substitution mode is the most favorable way in achieving slightly negative Δ and large values; the conjugated substituent will compete with heptazine to make the molecule deviate from the INVEST feature.

The Emerging Strategy of Symmetry Breaking for Enhancing Energy Conversion and Storage Performance.

Symmetry breaking has emerged as a novel strategy to enhance energy conversion and storage performance, which refers to changes in the atomic configurations within a material reducing its internal symmetry. According to the location of the symmetry breaking, it can be classified into spontaneous symmetry breaking within the material, local symmetry breaking on the surface of the material, and symmetry breaking caused by external fields outside the material. However, there are currently few summaries in this field, so it is necessary to summarize how symmetry breaking improves energy conversion and storage performance.

One-step detection of nanoplastics in aquatic environments using a portable SERS chessboard substrate.

Nanoplastics present a significant hazard to both the environment and human health. However, the development of rapid and sensitive analysis techniques for nanoplastics is limited by their small size, lack of specificity, and low concentrations. In this study, a surface-enhanced Raman scattering (SERS) chessboard substrate was introduced as a multi-channel platform for the pre-concentration and detection of nanoplastics, achieved by polydomain aggregating silver nanoparticles (PASN) on a hydrophilic and a punched hydrophobic PVDF combined filter membrane.

Tailored Polymer Hole-Transporting Materials with Multisite Passivation Functions for Effective Buried-Interface Engineering of Inverted Quasi-2D Perovskite Solar Cells.

Although quasi-2D Ruddlesden‒Popper (RP) perovskite exhibits advantages in stability, their photovoltaic performance are still inferior to 3D counterparts. Optimizing the buried interface of RP perovskite and suppress energetic losses can be a promising approach for enhancing efficiency and stability of inverted quasi-2D RP perovskite solar cells (PSCs). Among which, constructing polymer hole-transporting materials (HTMs) with defect passivation functions is of great significance for buried-interface engineering of inverted quasi-2D RP PSCs.

Correlation change analysis and NDVI prediction in the Yellow River Basin of China using complex networks and GRNN-PSRLSTM.

The Normalized Difference Vegetation Index (NDVI) is affected by various environmental factors, and its relationship with these factors is complex. In order to explore the complex relationship between NDVI and environmental factors, this paper adopts the complex network method to construct a correlation fluctuation network and analyze the interaction between them. It is found that temperature, precipitation, soil moisture, sunshine duration, and PM2.

Over 10% Efficiency Pure Sulfide Kesterite Solar Cells on Transparent Electrode with Cd-Ag Co-Alloying.

The environmentally friendly elements composed of high bandgap pure sulfide CuZnSnS (CZTS) semiconductor has broad prospects for building integrated photovoltaic, double-sided, and semi-transparent solar cells when fabricated on transparent substrates. The key issues limiting the performance of CZTS solar cells are poor absorber quality and unfavorable band energy alignment causing serious charge carrier recombination. Here, thefabrication of CZTS solar cells are reported on fluorine-doped tin oxide (FTO) substrates from dimethyl sulfoxide solution and the effects of the Cd and Ag alloying on device performance.

Remodeling the tumor immune microenvironment through hydrogel encapsulated G-Rh2 vaccine and systemic immunotherapy.

Ginsenoside Rh2 (G-Rh2) is a vital bioactive compound in Traditional Chinese Medicine, celebrated for its strong pharmacological properties, particularly its potent antitumor effects. However, its poor water solubility and limited bioavailability have necessitated the development of a novel drug delivery method. In this study, we utilized an indocyanine green carboxylic acid-hydroxypropyl cellulose-abietic acid-bovine serum albumin hydrogel (ICG-HPC-AA/BSA hydrogel) as a tumor vaccine to enhance the permeability, retention, and tumor-targeted therapeutic efficacy of G-Rh2.

Intelligent Modular DNA Lysosome-Targeting Chimera Nanodevice for Precision Tumor Therapy.

Lysosome targeting chimeras (LYTACs) have emerged as a powerful modality that can eliminate traditionally undruggable extracellular tumor-related pathogenic proteins, but their low bioavailability and nonspecific distribution significantly restrict their efficacy in precision tumor therapy. Developing a LYTAC system that can selectively target tumor tissues and enable a modular design is crucial but challenging. We here report a programmable nanoplatform for tumor-specific degradation of multipathogenic proteins using an intelligent modular DNA LYTAC (IMTAC) nanodevice.

Perceived stress and life satisfaction: the mediating roles of sport commitment and mobile phone addiction.

This study aimed to investigate the relationship between perceived stress and life satisfaction under the influence of mobile phone addiction and sport commitment. Participants were recruited from eight universities located in six Chinese cities, naming Chongqing, Maoming, Nanjing, Suzhou, Shijiazhuang, and Zhengzhou. The sample consisted of 575 participants enrolled in Chinese universities, with 309 (53.

Intrinsic Narrowband Blue Phosphorescent Materials and Their Applications in 3D Printed Self-monitoring Microfluidic Chips.

Organic room-temperature phosphorescent (RTP) materials, especially with narrowband emission properties, exhibit great potential for applications in display and sensing, but have been seldom reported. Herein, a rare example of the intrinsic narrowband blue RTP material is fabricated and reported. A series of indolo[3,2,1-kl]phenothiazine derivatives, named Cphpz, 1O-Cphpz, and 2O-Cphpz, are designed and synthesized.

Attention-Enhanced Defensive Distillation Network for Channel Estimation in V2X mm-Wave Secure Communication.

Millimeter-wave (mm-wave) technology, crucial for future networks and vehicle-to-everything (V2X) communication in intelligent transportation, offers high data rates and bandwidth but is vulnerable to adversarial attacks, like interference and eavesdropping. It is crucial to protect V2X mm-wave communication from cybersecurity attacks, as traditional security measures often fail to counter sophisticated threats and complex attacks. To tackle these difficulties, the current study introduces an attention-enhanced defensive distillation network (AEDDN) to improve robustness and accuracy in V2X mm-wave communication under adversarial attacks.

Multi-Frequency Asymmetric Absorption-Transmission Metastructures-Photonic Crystals and Their Application as a Refractive Index Sensor.

In this paper, a kind of metastructure-photonic crystal (MPC) with multi-frequency asymmetric absorption-transmission properties is proposed. It is composed of various dielectric layers arranged in a periodically tilting pattern. When electromagnetic waves (EMWs) enter from the opposite direction, MPC shows an obvious asymmetry.

A UAV Thermal Imaging Format Conversion System and Its Application in Mosaic Surface Microthermal Environment Analysis.

UAV thermal infrared remote sensing technology, with its high flexibility and high temporal and spatial resolution, is crucial for understanding surface microthermal environments. Despite DJI Drones' industry-leading position, the JPG format of their thermal images limits direct image stitching and further analysis, hindering their broad application. To address this, a format conversion system, ThermoSwitcher, was developed for DJI thermal JPG images, and this system was applied to surface microthermal environment analysis, taking two regions with various local zones in Nanjing as the research area.