Intelligent Point Cloud Processing, Sensing, and Understanding.

Point clouds are considered one of the fundamental pillars for representing the 3D digital landscape [...

Thermally generated Au-Ag nanostructures with tunable localized surface plasmon resonance as SERS activity substrates.

Various Au-Ag bimetallic alloy nanostructures were obtained as sensitive surface-enhanced Raman scattering (SERS) substrates by changing the thermal annealing sequence. The atomic force microscopy (AFM) and scanning electron microscopy (SEM) results confirm that Au/Ag bimetallic clusters and Ag-Au core-shell like structures can be designed by thermal annealing. The absorption spectra showed that the localized surface plasmon resonance (LSPR) frequency of the annealed Au/Ag bimetallic alloy structure could effectively shift from the near ultraviolet to the visible region.

NIR-Triggered On-Demand Nitric Oxide Release for Enhanced Synergistic Phototherapy of Hypoxic Tumor.

Hypoxia of tumor microenvironments is a major factor restricting tumor treatment, which causes progression and metastasis of tumor. The hypoxic tumor microenvironment not only makes the traditional treatment method, such as chemotherapy, ineffective but also hinders the O-dependent treatments, such as photodynamic therapy (PDT). Recently, stimuli-responsive nitric oxide (NO) donors have attracted extensive research interest in hypoxic tumor treatment because the NO release process is O-independent.

Gridization-Driven Mesoscale Self-Assembly of Conjugated Nanopolymers into Luminescence-Anisotropic Photonic Crystals.

Organic semiconducting emitters integrated with butterfly-mimetic photonic crystals (PhCs) are fascinating for dramatic advantages over light outcoupling efficiency and multifunctional strain sensors, as well as the key step toward electrically pumped lasers. Herein, an unprecedentedly direct mesoscale self-assembly into 1D PhCs is reported through a covalently gridization-driven approach of wide-bandgap conjugated polymers. A simple solvent-casting procedure allows for in situ self-assembly of the state-of-the-art conjugated nanopolymer, poly{[4-(octyloxy)-9,9-diphenylfluoren-2,7-diyl]grid}-co-{[5-(octyloxy)-9,9-diphenylfluoren-2,7-diyl]grid} (PODPFG), into well-defined multilayer architectures with an excellent toughness (30-40 J m ).

Feasible polarised white-light emission based on conjugate plane-structured yellow/blue dye molecules encapsulated in metal-organic frameworks.

We use a two-stage hierarchical growth method to encapsulate the blue KSN and yellow RhB molecules into a MOF crystal. By aligning these two conjugate plane-structured molecules in the MOF channel, a polarised white-light emission is obtained, with CIE coordinates of (0.3285, 0.

Overcoming Tumor Hypoxia through Multiple Pathways Using an All-in-One Polymeric Therapeutic Agent to Enhance Synergistic Cancer Photo/Chemotherapy Effects.

Hypoxia is a significant characteristic of tumors, which causes aggressive tumor growth and strong therapy resistance. Inspired by the improved therapeutic efficacy of synergistic treatment, herein, an all-in-one polymeric therapeutic agent was developed, which could overcome tumor hypoxia through multiple pathways. Multiple therapeutic agents were incorporated into the polymer, including the singlet oxygen (O) carrier unit to store cytotoxic reactive oxygen species, the photosensitized and photothermal unit to trigger the capture and release of O, and the hypoxia-responsive prodrug unit to maintain a long-term tumor inhibition.

Identification of miR-210 and combination biomarkers as useful agents in early screening non-small cell lung cancer.

Background: Recently, extensive researches have explored the potential biomarker roles of microRNA-210 (miR-210) in non-small cell lung cancer (NSCLC). Inconsistent results, however, have prevented its widespread use in diagnosis. In the present study, we aimed to clarify the biomarker roles of miR-210 in NSCLC through a comprehensive meta-analysis and an integrative bioinformatics analysis.

Identification of biomarker microRNA-mRNA regulatory pairs for predicting the docetaxel resistance in prostate cancer.

: Docetaxel resistance is a cursing problem with adverse effects on the therapeutic efficacy of prostate cancer (PCa), involving interactions among multiple molecular components. Single or limited molecules are not strong enough as prediction biomarkers of drug resistance. Network biomarkers are considered to outperform individual markers in disease characterization.

Integrated analyses of microRNA-29 family and the related combination biomarkers demonstrate their widespread influence on risk, recurrence, metastasis and survival outcome in colorectal cancer.

Background: Emerging evidence has revealed miR-29 family as promising biomarkers for colorectal cancer (CRC), but their biomarker potential and molecular mechanisms remain poorly understood.

Methods: We performed a comprehensive meta-analysis to evaluate the biomarker performance of individual miR-29 and the related miRNA combination biomarkers. Meanwhile, we conducted an integrative bioinformatics analysis to unfold the underlying biological function of miR-29 and their relationship with CRC.

Public Key-Based Authentication and En-Route Filtering Scheme in Wireless Sensor Networks.

The existing public key-based en-route filtering schemes are vulnerable to report disruption attacks or selective forwarding attacks, and they fail to consider any measure to detect and punish the malicious nodes. The authors propose a series of public key-based security mechanisms for wireless sensor networks (WSNs) in this paper, including a mechanism for verifying the partial signatures, a substitution mechanism, an effective report forwarding protocol, and a trust value-based mechanism to identify and punish the malicious nodes. Finally, the authors develop a public key-based authentication and en-route filtering scheme (PKAEF), which can resist false data injection attacks, report disruption attacks and selective forwarding attacks, and can mitigate the impact of malicious nodes.

Graphene/Polyaniline Aerogel with Superelasticity and High Capacitance as Highly Compression-Tolerant Supercapacitor Electrode.

Superelastic graphene aerogel with ultra-high compressibility shows promising potential for compression-tolerant supercapacitor electrode. However, its specific capacitance is too low to meet the practical application. Herein, we deposited polyaniline (PANI) into the superelastic graphene aerogel to improve the capacitance while maintaining the superelasticity.

Coverage-guaranteed sensor node deployment strategies for wireless sensor networks.

Deployment quality and cost are two conflicting aspects in wireless sensor networks. Random deployment, where the monitored field is covered by randomly and uniformly deployed sensor nodes, is an appropriate approach for large-scale network applications. However, their successful applications depend considerably on the deployment quality that uses the minimum number of sensors to achieve a desired coverage.