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Article Synopsis
  • A 65-year-old man developed bilateral pulmonary nodules one year after bladder cancer surgery, which were later identified as synchronous double primary lung cancer (sDPLC) instead of metastases from the bladder cancer.
  • Immunohistochemical analysis ruled out the nodules being metastases, while next-generation sequencing (NGS) confirmed their distinct origins, supporting the diagnosis of sDPLC.
  • The patient was ultimately diagnosed with small cell lung carcinoma (SCLC) and received chemotherapy, highlighting the importance of both immunohistochemical methods and NGS in accurate tumor classification and treatment planning.
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