3 results match your criteria: "Nanjing Normal University (NNU)[Affiliation]"
Rapidly self-crosslinking sodium alginate hydrogel for infected wounds.
J Biomater Sci Polym Ed
January 2025
School of Chemistry and Materials Science, National and Local Joint Engineering Research Center of Biomedical Functional Materials, Nanjing Normal University (NNU), Nanjing, China.
The risks associated with wound infections are significant, making a snug-fitting hydrogel dressing an optimal choice for wound management. For it, we employed the self-cross-linking method of oxidized sodium alginate (SCSA), incorporating clarithromycin (Cla) and basic fibroblast growth factor (bFGF) to formulate a rapidly forming, bacteriostatic, and wound-healing hydrogel (SCSA@C/b). Bacteriostatic and cytocompatibility assays demonstrated that SCSA@C/b exhibits exceptional antibacterial activity alongside strong biocompatibility.
View Article and Find Full Text PDFRapidly molded sodium alginate/soy protein adhesive hydrogel with 808-nm laser inhibition of infected wounds.
Int J Biol Macromol
November 2024
Department of Otolaryngology Head and Neck Surgery, Affiliated Drum Tower Hospital of Nanjing University Medical School, Jiangsu Provincial Medical Key Discipline (Laboratory), Research Institute of Otolaryngology, Nanjing 210008, China; Department of Otolaryngology Head and Neck Surgery, Nanjing Drum Tower Hospital Clinical College of Nanjing University of Chinese Medicine, Jiangsu Provincial Medical Key Discipline (Laboratory), Research Institute of Otolaryngology, Nanjing 210008, China. Electronic address:
Infected wounds produce pus and heal slowly. To address this issue, we developed a rapid-setting SP/SA@BP-C hydrogel by combining sodium alginate (SA) and soy protein (SP) with black phosphorus (BP) grafted with clarithromycin (Cla) and incorporating Ca for chelation. This hydrogel dressing exhibits excellent photothermal (PT) and photodynamic (PD) bacteriostatic effects without biotoxicity, making it suitable for treating infected wounds.
View Article and Find Full Text PDFUnlocking growth potential in Halomonas bluephagenesis for enhanced PHA production with sulfate ions.
J Ind Microbiol Biotechnol
January 2024
Biotechnology Center, COFCO Nutrition and Health Research Institute Co., Ltd., Beijing, 102209, China.
Article Synopsis
- A mutant strain of Halomonas bluephagenesis (TDH4A1B5P) was identified to produce polyhydroxyalkanoates (PHA) under low-salt, non-sterile conditions, albeit with low yield initially.
- To enhance PHA production, different nitrogen sources were tested, revealing urea as most effective during stable growth and ammonium sulfate during logarithmic growth, with sulfate ions significantly extending growth time and PHA content.
- Through an optimized feeding strategy using nitrogen sources and sulfate ions, the culture achieved a dry cell weight of 124 g/L and PHA content of 82.3%, resulting in a PHA yield of 101 g/L in a bioreactor