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Pulmonary enteric adenocarcinoma: a study of the clinicopathologic and molecular status of nine cases.
Int J Clin Exp Pathol
December 2014
Department of Pathology, Clinical School of Medical College of Nanjing University, Nanjing Jingling Hospital Nanjing, China.
Article Synopsis
- Pulmonary enteric adenocarcinoma (PEAC) is a rare type of lung cancer, identified as a distinct variant by an international classification in 2011, notable for its tall columnar cells resembling intestinal lining.
- The study examined 9 cases of PEAC alongside 20 cases of metastatic colorectal cancer (MCR) and typical primary adenocarcinoma (tPAC), focusing on immunohistochemical markers to differentiate them.
- Findings revealed that PEAC consistently expressed CK7, lacked common mutations seen in typical lung adenocarcinomas, and had unique characteristics that distinguish it from other cancer types.