994 results match your criteria: "Nanchong Central Hospital[Affiliation]"
Clin Exp Dermatol
December 2024
Department of Dermatology, the First Affiliated Hospital of Fujian Medical University, 20 Chazhong Road, Fuzhou, Fujian, China.
BMC Anesthesiol
December 2024
Department of Anesthesiology, The Second Clinical Medical College, North Sichuan Medical College, Nanchong Central Hospital, Nanchong, China.
Background: Ciprofol, a novel intravenous anesthetic, exhibits similar sedation mechanisms and pharmacokinetic properties to propofol. However, ciprofol demonstrates greater potency and is associated with reduced injection pain compared to propofol. Given the varying sensitivities to anesthetic agents across different age groups, this study aims to determine the median effective dose (ED) of ciprofol required to suppress the laryngeal mask airway (LMA) insertion response in both young and older adult patients, as well as to assess its potential adverse reactions.
View Article and Find Full Text PDFFront Genet
December 2024
Affiliated Hospital of North Sichuan Medical College, Nanchong, Sichuan, China.
[This corrects the article DOI: 10.3389/fgene.2024.
View Article and Find Full Text PDFTechnol Cancer Res Treat
December 2024
Institute of Tissue Engineering and Stem Cells, Beijing Anzhen Nanchong Hospital, Capital Medical University & Nanchong Central Hospital, The Second Clinical Medical College of North Sichuan Medical College, Nanchong 63700, China.
Background: A clinical challenge in esophageal squamous cell carcinoma (ESCC) remains the lack of applicable plasma biomarkers for screening and diagnosis. Circular RNAs (circRNAs) hold great potential as biomarkers for cancer. The study aims to explore a circRNA as a potential plasma biomarker for screening strategies and diagnostic approaches to ESCC.
View Article and Find Full Text PDFAcad Radiol
December 2024
Department of Ultrasound, The first affiliated hospital of Anhui Medical University, Hefei, Anhui 230022, China (X.Q., X.L., Q.L., L.X., C.Z.). Electronic address:
Rationale And Objectives: To develop an interpretable deep learning (XDL) model based on superb microvascular imaging (SMI) for the noninvasive diagnosis of the degree of interstitial fibrosis (IF) in chronic kidney disease (CKD).
Methods: We included CKD patients who underwent renal biopsy, two-dimensional ultrasound, and SMI examinations between May 2022 and October 2023. Based on the pathological IF score, they were divided into two groups: minimal-mild IF (≤25%) and moderate-severe IF (>25%).
Am J Transl Res
November 2024
Department of Neurosurgery, Chongqing General Hospital, Chongqing University Chongqing 401147, China.
Background: Postoperative cerebrospinal fluid (CSF) leak is a life-threatening complication following endoscopic skull base surgery. This study describes a multilayered membrane reconstruction strategy for treating high-flow intraoperative CSF leaks during expanded endoscopic endonasal tumor resection (EEA) and presents the associated outcomes, supplemented by surgical video documentation.
Methods: A retrospective review was performed on patients who underwent multilayered membrane reconstruction for high-flow CSF leaks during EEA.
Neurol Sci
December 2024
Department of Neurosurgery, The Second Clinical Medical College, Nanchong Central Hospital, North Sichuan Medical College, No. 97 Renmin South Road, Nanchong, Sichuan, 637000, China.
J Alzheimers Dis
December 2024
Department of Neurology, Huashan Hospital, Fudan University, Shanghai, China.
Front Neurol
November 2024
Department of Neurosurgery, Nanchong Central Hospital/The Second Clinical Medical College, North Sichuan Medical College, Nanchong, China.
Background: The thrombocytopenia influences prognoses of critically ill patients. There are few studies exploring the prognostic value of thrombocytopenia among ICH patients. We perform this study to explore the correlation between thrombocytopenia at different timepoints of hospitalizations and mortality of ICH.
View Article and Find Full Text PDFJ Chemother
December 2024
Department of Obstetrics and Gynecology, Maternal and Child Health Hospital of Cangxi County, Guangyuan City, Sichuan Province, P. R. China.
Cervical cancer is one of the most common gynecologic malignancies worldwide. 5-Fluorouracil (5-Fu) is a widely used anticancer drug for various cancers, but the development of 5-Fu resistance poses a challenge in treating cervical cancer patients. This study examined the roles and molecular mechanisms of LncRNA-FGD5-AS1 in 5-Fu resistant cervical cancer cells through in vitro and in vivo experiments.
View Article and Find Full Text PDFEpidemiol Health
November 2024
Chongqing General Hospital, Chongqing University, Chongqing, China.
Objectives: Existing evidence suggests that miscarriage and stillbirth are associated with an increased risk of stroke in women. However, the impact of these events on stroke mortality remains unclear. This study aimed to elucidate the potential association between miscarriage and stillbirth and stroke mortality in women.
View Article and Find Full Text PDFJ Endocrinol Invest
December 2024
Department of Urology, Xiangya Hospital, Central South University, 87 Xiangya Road, Changsha, 410008, Hunan, China.
Objective: This systematic review aims to synthesise findings from randomised, controlled trials and assess the efficacy and safety of radiofrequency ablation in treating allergic rhinitis.
Methods: A thorough search was conducted across PubMed, the Cochrane Library, Embase, Web of Science, China National Knowledge Infrastructure, WanFang, Chinese Scientific Journal, and Chinese Biomedical Literature databases from their inception until October 2023. The primary outcome measure was the total effective rate, with secondary outcomes including adverse events.
Clin Respir J
December 2024
Department of Clinical Laboratory, Beibei Traditional Chinese Medical Hospital, Chongqing, China.
Immunotherapy is a pivotal approach in the treatment of lung cancer. Although HLA-E is a potential target for tumor immunotherapy, its role in lung cancer remains unclear. Previous studies have identified the transcription factor IRF5 as a characteristic gene of M1-like macrophages, highlighting its crucial role in promoting antitumor immune responses.
View Article and Find Full Text PDFPeerJ
December 2024
Department of Paediatric Surgery, Nanchong Central Hospital, Nanchong, Sichuan, China.
Autoimmun Rev
November 2024
Department of Rheumatology and Immunology, Beijing Anzhen Nanchong Hospital, Capital Medical University & Nanchong Central Hospital, The Affiliated Nanchong Central Hospital of North Sichuan Medical College, Nanchong, Sichuan, China; Inflammation and Immunology Key Laboratory of Nanchong City, Nanchong, Sichuan, China; Nanchong Central Hospital, (Nanchong Clinical Research Center), Nanchong, Sichuan, China. Electronic address:
J Integr Neurosci
November 2024
Department of Neurology, Affiliated Hospital of North Sichuan Medical College, 637000 Nanchong, Sichuan, China.
Introduction: This research aimed to investigate the pathophysiological mechanism of how drug-induced parkinsonism (DIP) affects the integrity of the white matter (WM) fiber microstructure as measured by magnetic resonance diffusion tensor image (DTI) fractional anisotropy (FA) and mean diffusivity (MD).
Methods: We recruited 17 participants diagnosed with DIP, 20 Parkinson's disease (PD) patients, and 16 normal controls (NCs) with a similar age, gender, and years of education. Subsequently, all participants underwent DTI magnetic resonance imaging scanning.
Front Pharmacol
November 2024
Luzhou Key Laboratory of Traditional Chinese Medicine for Chronic Diseases Jointly Built by Sichuan and Chongqing, The Affiliated Traditional Chinese Medicine Hospital, Southwest Medical University, Luzhou, Sichuan, China.
Chemotherapy remains the first choice of treatment for colon cancer despite the inevitable adverse effects. Curcumin (CU) possesses antitumor activity but has poor aqueous solubility, low bioavailability, and weak activity. To address this, nine novel monocarbonyl CU analogues were designed, synthesized, and evaluated in the present study.
View Article and Find Full Text PDFFront Endocrinol (Lausanne)
November 2024
Department of Neurosurgery, Nanchong Central Hospital, The Second Clinical Medical College, North Sichuan Medical College, Nanchong, Sichuan, China.
[This corrects the article DOI: 10.3389/fendo.2024.
View Article and Find Full Text PDFMedicine (Baltimore)
November 2024
Department of Otorhinolaryngology Head and Neck Surgery, Nanchong Central Hospital, The Second Clinical Medical College, Nanchong, China.
Therap Adv Gastroenterol
November 2024
Department of Gastroenterology, Nanchong Central Hospital, The Second Clinical Medical College, North Sichuan Medical College, Nanchong, China.
Background: Esophageal-gastric variceal bleeding (EGVB) is a serious complication in patients with liver cirrhosis, characterized by high mortality and rebleeding rates. The effect of sequential endoscopic therapy on patient mortality and rebleeding rates remains unclear.
Objectives: This study aimed to evaluate the effects of sequential endoscopic therapy on mortality and rebleeding rates in patients with EGVB.
World J Mens Health
October 2024
Department of Urology, Gyeongsang National University College of Medicine and lnstitute of Health Sciences of Gyeongsang National University, Jinju, Korea.
Purpose: The K-FRAIL scale is a Korean version of the aging questionnaire that allows screening and diagnosis of easily observable aging in the elderly through a simple self-answer questionnaire. The objective of this study was to examine the relation between fraility and clinical symptoms of the lower urinary tract in elderly men using the K-FRAIL scale.
Materials And Methods: A prospective study was conducted on 100 patients who underwent urological examination at our hospital from January 2021 to December 2021.
Front Immunol
November 2024
Department of Orthopaedics, Nanchong Central Hospital, The Second Clinical Institute of North Sichuan Medical College, Nanchong, China.
Background: Rheumatoid arthritis (RA), a chronic autoimmune condition, is characterized by persistent synovial inflammation, bone degradation, and progressive joint deterioration. Despite considerable research efforts, the precise molecular mechanism underlying RA remains elusive. This investigation aims to elucidate the potential role and molecular mechanism of N6-methyladenosine (mA) methylation regulators in the pathogenesis of RA.
View Article and Find Full Text PDFEndoscopy
December 2023
Department of Gastroenterology, Nanchong Central Hospital, The Second Clinical Medical College, North Sichuan Medical College, Nanchong, China.
Adv Clin Exp Med
November 2024
Institute of Basic Medicine and Forensic Medicine, North Sichuan Medical College, Nanchong, China.
Background: Melanoma is an aggressive skin malignancy with rapid metastasis and high morbidity. Gedunin (GN) is a tetranortriterpenoid belonging to the Meliaceae family, described for its anticancer, antiproliferative and apoptotic properties.
Objectives: In the present study, we investigated the effect of GN on A431 melanoma cell proliferation and apoptosis.