3 results match your criteria: "Nagoya City University West Medical Centre[Affiliation]"
Concentrations of Neonicotinoid insecticides and their metabolites in multiple urine samples collected from pregnant women in Japan.
Environ Res
October 2023
Japan Environment and Children's Study Office, Health and Environmental Risk Division, National Institute for Environmental Studies, 16-2 Onogawa, Tsukuba, Ibaraki, 305-0086, Japan. Electronic address:
Article Synopsis
- Exposure to low doses of neonicotinoid insecticides during pregnancy may negatively affect children's neurodevelopment, prompting researchers to investigate urinary biomarkers of exposure in pregnant women.
- The study involved collecting urine samples from 30 non-smoking pregnant women in Japan over a two-week period, measuring concentrations of neonicotinoid metabolites using advanced mass spectrometry techniques.
- Results indicated that while certain metabolites like N-desmethyl-acetamiprid showed moderate reproducibility as exposure biomarkers, other neonicotinoids displayed poor reproducibility, suggesting that multiple urine samples are needed for accurate assessments of overall exposure.
Surgical antimicrobial prophylaxis in Japanese hospitals: Real status and challenges.
J Infect Chemother
July 2024
Department of Infectious Diseases, Nagoya University Hospital, Nagoya, Japan.
Article Synopsis
- - The study investigated surgical antimicrobial prophylaxis (SAP) practices in Japanese hospitals, revealing a lack of data on guidelines adherence and prescription standards.
- - Conducted across 27 hospitals, the survey found that only 33.9% of surgeries met appropriateness criteria, with a notable variability among surgical fields and hospitals regarding proper antimicrobial selection.
- - Results indicated that while cefazolin was commonly used, there is a pressing need for ongoing monitoring and interventions to enhance SAP compliance nationwide.
Evidence of both foetal inflammation and hypoxia-ischaemia is associated with meconium aspiration syndrome.
Sci Rep
August 2021
Department of Pediatrics, Nagoya City University West Medical Centre, Nagoya, Japan.
Article Synopsis
- Foetal hypoxia-ischaemia is a major cause of meconium aspiration syndrome (MAS), but many cases occur without clear hypoxia signs, indicating other risk factors may be at play.
- In a study of 1,336 neonates with meconium-stained amniotic fluid, 6.6% developed MAS, with links found to low Apgar scores, low cord blood pH, funisitis, and elevated inflammatory proteins at birth.
- The final analysis highlighted that lower cord blood pH, presence of funisitis, and higher levels of α-acid glycoprotein were significant independent factors for MAS development, suggesting intrauterine inflammation plays an important role alongside hypoxia.