11 results match your criteria: "Nagakubo Hospital.[Affiliation]"

(Objective) Recently, lower urinary tract symptoms (LUTS) were reported to be associated with endothelial dysfunction. Endothelial function is non-invasively measured by flow-mediated dilation (FMD). As tadalafil has the potential to improve atherosclerosis, we evaluated the relationship between LUTS and endothelial function using FMD, and the effects of tadalafil.

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  • Postprostatectomy incontinence is a common issue after prostate surgery, and this study investigates how pelvic floor muscle movements impact recovery of bladder control using cine MRI technology.
  • The study involved 128 prostate cancer patients undergoing robotic surgery, comparing preoperative and postoperative bladder elevation distances to explore their relationship with recovery outcomes.
  • Results showed that a longer preoperative bladder elevation distance (greater than 8.5 mm) was linked to faster recovery of continence, suggesting that this measurement could help in evaluating risks and guiding rehabilitation efforts post-surgery.
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Numerous reports point to the beneficial effects of testosterone replacement therapy for patients with late-onset hypogonadism (LOH) syndrome. The aim of this study was to evaluate the effect of intramuscular injection of testosterone enantholactam acid ester on Aging Males' Symptoms (AMS) scores in hemodialysis patients with LOH. A total of 24 male patients with LOH (total AMS scores ≥27) were randomized into groups receiving intramuscular injections of either placebo or testosterone enantholactam acid ester at the dose of 250 mg for 6 months.

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Endothelial dysfunction, abnormal vascular structure and lower urinary tract symptoms in men and women.

Int J Cardiol

June 2018

Division of Regeneration and Medicine, Medical Center for Translational and Clinical Research, Hiroshima University Hospital, Hiroshima, Japan; Department of Cardiovascular Regeneration and Medicine, Research Institute for Radiation Biology and Medicine, Hiroshima University, Hiroshima, Japan. Electronic address:

Background: Lower urinary tract symptoms (LUTS) is not only common symptoms in elderly men and women but also risk of future cardiovascular events. The purpose of this study was to evaluate the relationships of vascular function and structure with LUTS in men and women.

Methods: We investigated flow-mediated vasodilation (FMD) and nitroglycerine-induced vasodilation (NID) as vascular function, brachial-ankle pulse wave velocity (baPWV) as vascular structure, and LUTS assessed by International Prostate Symptom Score (IPSS) in 287 men and 147 women.

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(Purpose) Photoselective vaporization of the prostate (PVP) was introduced in Japan about 10 years ago, and there has been few studies regarding long-term outcomes so far. Herein we report our 10-year follow up result of PVP. (Patients and methods) From January 2006 to June 2006, 31 patients with benign prostatic hyperplasia (BPH) underwent PVP and 20 patients were evaluable in 10 years after PVP.

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  • The study evaluated the long-term effectiveness of photoselective vaporization of the prostate (PVP) for treating benign prostatic enlargement and obstruction in 457 patients over a 5-year period.
  • Results showed significant and lasting improvements in urinary symptoms, quality of life, and urinary flow rates, with a 43% reduction in prostate volume by the first year remaining stable up to five years.
  • The treatment was found to be more effective for patients with larger prostates, with only 1.1% requiring additional surgery for recurrence of symptoms.
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Objective: To investigate the superiority in 2 radical prostatectomies, we compared the initial results of robotic-assisted radical prostatectomy (RARP) to those of retropubic radical prostatectomy (RRP) performed during the same period at Nagakubo hospital.

Patients And Methods: The study was conducted on a total of 160 patients having undergone radical prostatectomy from April 2009 to March 2012 (92 patients with RARP and 68 with RRP). We investigated surgical stress, cancer control, functional outcomes and complications in both groups.

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Purpose: Teneligliptin is a novel DPP-4 inhibitor in development for treating type 2 diabetes mellitus that does not require dose adjustment for diabetic patients with end-stage renal disease; however, it had not been known whether or not teneligliptin is safe or potent in dialysis patients. We conducted a prospective study to assess the utility of teneligliptin for diabetic patients undergoing hemodialysis.

Methods: Blood glucose, glycated albumin, and HbA1c were measured every 4 weeks, at 4, 12, 20, and 28 weeks, and every 8 weeks, respectively, for patients treated with teneligliptin (n = 14; 7 patients newly started and 7 that switched from other medications) and patients of a control group who continued ongoing antidiabetic therapy (n = 29).

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  • The study aimed to evaluate the safety and effectiveness of mirabegron for patients with overactive bladder (OAB) who do not respond to antimuscarinic medications or have benign prostatic hyperplasia (BPH).
  • A total of 97 patients were treated with mirabegron and showed significant improvement in OAB symptoms, with an effectiveness rate of 85.2% in newly diagnosed patients and 61.6% in those unresponsive to antimuscarinics.
  • The results indicated that mirabegron is comparable to antimuscarinic treatments, improves symptoms related to BPH, and has a low incidence of mild side effects, supporting its safe use.
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Objective: To assess the efficacy and safety of transurethral resection in saline vaporization for symptomatic bladder outlet obstruction and the change in prostate volume.

Methods: A total of 106 patients with symptomatic bladder outlet obstruction underwent transurethral resection in saline vaporization. The effectiveness of the treatment was evaluated using the International Prostate Symptom Score (IPSS), quality of life score, urinary peak flow, and prostate volume preoperatively and at 1, 3, 6, and 12 months postoperatively.

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  • The study evaluates the effectiveness and safety of Photoselective Vaporization of the Prostate (PVP) in patients who cannot undergo traditional TUR-P due to severe heart disease or cognitive impairments.
  • A total of 312 patients were treated, with 12 specifically analyzed: 8 with severe heart issues and 4 with significant dementia, showing no intraoperative complications and a successful procedure.
  • Post-surgery results revealed improved urinary flow without the need for blood transfusions or complications like hyponatremia, and all patients successfully urinated after catheter removal, indicating positive outcomes from the PVP procedure.
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