2 results match your criteria: "NZ Brain Research Institute[Affiliation]"
Reproducibility and repeatability of magnetic resonance imaging in dementia.
Phys Med
September 2022
Brain Research New Zealand - Rangahau Roro Aotearoa, Centre of Research Excellence, New Zealand; Department of Medicine, University of Otago, Christchurch, New Zealand; NZ Brain Research Institute, Christchurch, New Zealand; School of Psychology, Speech and Hearing, University of Canterbury, Christchurch, New Zealand.
Purpose: Individualised predictive models of cognitive decline require disease-monitoring markers that are repeatable. For wide-spread adoption, such markers also need to be reproducible at different locations. This study assessed the repeatability and reproducibility of MRI markers derived from a dementia protocol.
View Article and Find Full Text PDFSpatial variation of perfusion MRI reflects cognitive decline in mild cognitive impairment and early dementia.
Sci Rep
December 2021
School of Psychology and Centre for Brain Research, The University of Auckland, Building 302, Level 2, 23 Symonds Street, Private Bag 92019, Auckland, 1142, New Zealand.
Cerebral blood flow (CBF) measured with arterial spin labelling (ASL) magnetic resonance imaging (MRI) reflects cerebral perfusion, related to metabolism, and arterial transit time (ATT), related to vascular health. Our aim was to investigate the spatial coefficient of variation (sCoV) of CBF maps as a surrogate for ATT, in volunteers meeting criteria for subjective cognitive decline (SCD), amnestic mild cognitive impairment (MCI) and probable Alzheimer's dementia (AD). Whole-brain pseudo continuous ASL MRI was performed at 3 T in 122 participants (controls = 20, SCD = 44, MCI = 45 and AD = 13) across three sites in New Zealand.
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