12 results match your criteria: "NTT East Medical Center Sapporo[Affiliation]"

Article Synopsis
  • The study aimed to evaluate if angiotensin type 1 receptor blockers (ARBs) or ACE inhibitors (ACEis) can help reduce the size of coronary artery aneurysms (CAA) in Kawasaki disease (KD) patients.
  • Conducted in Japan, the research involved 209 patients diagnosed with KD and medium to large CAAs, with a significant portion also using ARBs/ACEis.
  • Although both groups had similar overall CAA regression rates, those taking ARBs/ACEis showed a higher regression rate for giant CAAs, suggesting potential benefits of these medications, especially in more severe cases.
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Aim: The aim of this study is to investigate whether the results of pelvimetry using original radiographic Martius images and the same images with high-pass filtering applied ("edge images") would be consistent.

Methods: A total of 30 primagravidas were included in this study. Three obstetricians independently measured the anteroposterior and transverse diameters of the pelvic inlet in the original and the edge images, recording the x- and y-coordinates of the four endpoints.

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Purpose: To explore pre-treatment risk factors for overall survival (OS) in advanced urothelial carcinoma (UC) patients treated with first-line (1L) chemotherapy in sequential therapy (ST) era. Additionally, to evaluate the proportion of patients who were not able to undergo subsequent immune checkpoint inhibitor (ICI) therapy according to the subgroups stratified by the risk factors.

Methods: A multicenter retrospective study was conducted.

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Article Synopsis
  • The study aimed to assess how effective local radiation therapy (LRT) is in preventing local symptoms associated with muscle-invasive bladder cancer (MIBC) by reviewing 133 patient records over five years.
  • Out of 114 patients analyzed, 26.3% experienced local symptoms such as hematuria and bladder pain, with certain risk factors like previous non-MIBC and lower radiation doses identified.
  • The findings suggest that increasing the radiation dose to 50 Gray or more could help reduce these local symptoms and improve care strategies for MIBC patients expected to have good survival outcomes.
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Early diagnosis and initiation of treatment for fresh osteoporotic lumbar vertebral fractures (OLVF) are crucial. Magnetic resonance imaging (MRI) is generally performed to differentiate between fresh and old OLVF. However, MRIs can be intolerable for patients with severe back pain.

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Purpose: There is controversy regarding which internal thoracic artery (ITA) should be anastomosed to the left anterior descending artery (LAD). Here, we propose an optimal graft design based on measurement of blood flow in the ITA.

Methods: Sixty-one patients (53 men, median age 68 [62-75] years) undergoing first elective coronary artery bypass grafting were enrolled.

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An 86-year-old man was hospitalized urgently to our department because of his worsening hemoptysis. He had undergone open thoracic aortic grafting for the Stanford type B chronic aortic dissecting aneurysm 30 years earlier. Contrast enhanced computed tomography (CT) revealed the distal anastomotic aneurysm, leakage of the contrast medium around the distal anastomotic site.

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Article Synopsis
  • The study examines long-term outcomes for Kawasaki disease patients who develop coronary artery aneurysms (CAA), aiming to identify risk factors for coronary events (CE) and management strategies.
  • A total of 179 patients were followed for about 501 days, revealing that 7% experienced CEs, predominantly within the first two years after KD onset, with larger CAAs correlating with higher risks.
  • The research highlights that patients with larger CAAs are at significantly greater risk for CEs, suggesting that current antithrombotic treatments, like warfarin, may not adequately mitigate these risks, indicating a need for improved therapies.
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Introduction: Pembrolizumab is a programmed death-ligand 1 inhibitor that was initially indicated for monotherapy in patients with advanced lung cancer. The Japanese Lung Cancer Society conducted an observational study on pembrolizumab using confirmative data obtained through postmarketing all-case surveillance (PMACS), which was performed by a pharmaceutical company under the Japanese law in 2017.

Methods: This multicenter observational study was conducted by the Japanese Lung Cancer Society using PMACS data with the newly created central registration system regarding patients with NSCLC who received pembrolizumab monotherapy between February 1, 2017 and June 30, 2017; a new database was created by adding the clinical information regarding prognosis for 3 years after therapy to the existing data collected by PMACS.

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An 85-year-old man was being treated with anti-cancer drugs for adenocarcinoma of the lung and was on a tapering dose of prednisolone for interstitial pneumonia. He attended our hospital complaining of fatigue, thirst, and polyuria in September 2020. His postprandial plasma glucose concentration was 976 mg/dL, his glycated hemoglobin was 8.

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