Exercise Self-Efficacy and patient global assessment were associated with 6-min walk test distance in persons with rheumatoid arthritis.

Introduction: Low functional capacity is related to future loss of daily function and cardiovascular events. The present study explored the associations of patient-reported outcome measures (PROMs) and disease-specific measures with functional capacity as measured by the 6-min walk test (6MWT) in persons with rheumatoid arthritis (RA).

Methods: Seventy-nine participants from rheumatology outpatient clinics were included.

"I am not a Lady, I am a Scientist." Chemistry, Women, and Gender in the Enlightenment and the Era of Professional Science.

This article introduces a collection of papers on women, gender, and chemistry in eighteenth- and twentieth-century Europe and the United States. After briefly surveying previous research on women and gender in science and outlining the long history of women in chemistry, we present this special issue's main findings concerning several key themes, including the identities and strategies of women engaged in chemical activities and the enabling circumstances and networks that helped these women gain entry into male-dominated institutions and fields of study. We suggest that these overarching themes are equally relevant to the Enlightenment era and the late nineteenth- and early to mid-twentieth-century age of professional science, thus illustrating the benefits of jointly treating cases that might otherwise seem to have little in common.

Artificial intelligence for prostate MRI: open datasets, available applications, and grand challenges.

Artificial intelligence (AI) for prostate magnetic resonance imaging (MRI) is starting to play a clinical role for prostate cancer (PCa) patients. AI-assisted reading is feasible, allowing workflow reduction. A total of 3,369 multi-vendor prostate MRI cases are available in open datasets, acquired from 2003 to 2021 in Europe or USA at 3 T (n = 3,018; 89.

Norwegian Consumers' Skepticism towards Smoke-Flavoring of Salmon-Is It for Real?

The aim of the present study was to explore Norwegian consumers' attitudes toward smoke-flavoring of cold smoked salmon (CSS), by conducting a digital survey and focus group discussions. Some of the smoke-flavoring techniques, like atomized purified condensed smoke, is considered healthier than conventional smoking. Manufacturers of CSS are, however, hesitant to use all kinds of smoke-flavoring due to expected consumer skepticism.

The WHO 2021 Classification of Central Nervous System tumours: a practical update on what neurosurgeons need to know-a minireview.

Background: The World Health Organization (WHO) Classification of Tumours, also known as WHO Blue Books, represents an international standardised tool in the diagnostic work-up of tumours. This classification system is under continuous revision, and progress in the molecular classification of tumours in the central nervous system (CNS) enforced an update of the WHO 2016 classification, and the fifth edition, WHO CNS5, was published in 2021. The aim of this minireview is to highlight important changes in this new edition relevant for the practicing neurosurgeon.

The Multilingual Picture Database.

The growing interdisciplinary research field of psycholinguistics is in constant need of new and up-to-date tools which will allow researchers to answer complex questions, but also expand on languages other than English, which dominates the field. One type of such tools are picture datasets which provide naming norms for everyday objects. However, existing databases tend to be small in terms of the number of items they include, and have also been normed in a limited number of languages, despite the recent boom in multilingualism research.

Enabling Circumstances: Women Chemical Engineers at the Norwegian Institute of Technology, 1910-1943.

The Norwegian Institute of Technology (NTH) was the first of its kind when it opened doors in Trondheim in 1910. For the first time, engineers who were perceived as central to the country's industrial development could be educated in Norway. Of the 4,311 students admitted to NTH before 1940, twenty were women who embarked on the course in chemical engineering.

Removing Fluoride-Terminations from Multilayered VC MXene by Gas Hydrolyzation.

Two-dimensional MXenes have shown great promise for many different applications, but in order to fully utilize their potential, control of their termination groups is essential. Here we demonstrate hydrolyzation with a continuous gas flow as a method to remove F-terminations from multilayered VC particles, in order to prepare nearly F-free and partly bare vanadium carbide MXene. Density functional theory calculations demonstrate that the substitution of F-terminations is thermodynamically feasible and presents partly nonterminated VCO as the dominating hydrolyzation product.

Risk of cardiovascular disease in women and men with subfertility: the Trøndelag Health Study.

Objective: To investigate the association between subfertility and risk of cardiovascular disease (CVD) outcomes.

Design: Prospective study.

Setting: Population-based cohort.

Scandinavian Online Cancer Information as Expressions of Governmentality: A Comparative Qualitative Study.

We compared online distributed information provided to patients with cancer in Scandinavian countries through the lens of governmentality. A secondary comparative qualitative analysis was conducted. Discourses in online patient information showed differences in governmentality techniques across the countries: Norway used a paternalist approach, Denmark an educative approach, and Sweden an individualistic approach and expected the patients to make the "right" decisions.

The Third Dimension of Ferroelectric Domain Walls.

Ferroelectric domain walls are quasi-2D systems that show great promise for the development of nonvolatile memory, memristor technology, and electronic components with ultrasmall feature size. Electric fields, for example, can change the domain wall orientation relative to the spontaneous polarization and switch between resistive and conductive states, controlling the electrical current. Being embedded in a 3D material, however, the domain walls are not perfectly flat and can form networks, which leads to complex physical structures.

Experimental Tests and Numerical Simulations on the Ballistic Impact Response of a Highly Inhomogeneous Aluminium Foam.

A sandwich structure is a composite material consisting of thin skins encapsulating a cellular core. Such structures have proven to be excellent energy absorbents and are frequently found in various types of protection. Even so, few studies exist in the open literature on the response of the core material itself under extreme loadings such as blast and impact.

Migraine-attributed burden, impact and disability, and migraine-impacted quality of life: Expert consensus on definitions from a Delphi process.

Background: Migraine-attributed burden, impact, disability and migraine-impacted quality of life are important concepts in clinical management, clinical and epidemiological research, and health policy, requiring clear and agreed definitions. We aimed to formulate concise and precise definitions of these concepts by expert consensus.

Methods: We searched the terms migraine-attributed burden, impact, disability and migraine-impacted quality of life in Embase and Medline from 1974 and 1946 respectively.

Water as a monomer: synthesis of an aliphatic polyethersulfone from divinyl sulfone and water.

Using water as a monomer in polymerization reactions presents a unique and exquisite strategy towards more sustainable chemistry. Herein, the feasibility thereof is demonstrated by the introduction of the oxa-Michael polyaddition of water and divinyl sulfone. Upon nucleophilic or base catalysis, the corresponding aliphatic polyethersulfone is obtained in an interfacial polymerization at room temperature in high yield (>97%) within an hour.

DNA methylation changes in response to neoadjuvant chemotherapy are associated with breast cancer survival.

Background: Locally advanced breast cancer is a heterogeneous disease with respect to response to neoadjuvant chemotherapy (NACT) and survival. It is currently not possible to accurately predict who will benefit from the specific types of NACT. DNA methylation is an epigenetic mechanism known to play an important role in regulating gene expression and may serve as a biomarker for treatment response and survival.

Concordance Analysis between the Segments and the Overall Performance in Olympic Triathlon in Elite Triathletes.

To date, the performance in triathlon has been measured through time or position. Although this is what defines the medals and the goal of the competition, it can have some limitations. As an alternative, the purpose of this study is to assess the degree of concordance of performance between each of the triathlon disciplines with overall performance through the triathlon performance indicator for the Olympic distance event.

Evaluating the Impact of High Intensity Interval Training on Axial Psoriatic Arthritis Based on MR Images.

High intensity interval training (HIIT) has been shown to benefit patients with psoriatic arthritis (PsA). However, magnetic resonance (MR) imaging has uncovered bone marrow edema (BME) in healthy volunteers after vigorous exercise. The purpose of this study was to investigate MR images of the spine of PsA patients for changes in BME after HIIT.

The Riemannian Geometry Theory of Visually-Guided Movement Accounts for Afterimage Illusions and Size Constancy.

This discussion paper supplements our two theoretical contributions previously published in this journal on the geometric nature of visual space. We first show here how our Riemannian formulation explains the recent experimental finding (published in this special issue on size constancy) that, contrary to conclusions from past work, vergence does not affect perceived size. We then turn to afterimage experiments connected to that work.

Longitudinal Brain Changes After Stroke and the Association With Cognitive Decline.

Background: Cognitive impairment is common after stroke. So is cortical- and subcortical atrophy, with studies reporting more atrophy in the ipsilesional hemisphere than the contralesional hemisphere. The current study aimed to investigate the longitudinal associations between (I) lateralization of brain atrophy and stroke hemisphere, and (II) cognitive impairment and brain atrophy after stroke.

Postnatal development of projections of the postrhinal cortex to the entorhinal cortex in the rat.

The ability to encode and retrieve contextual information is an inherent feature of episodic memory that starts to develop during childhood. The postrhinal cortex, an area of the parahippocampal region, has a crucial role in encoding object-space information and translating egocentric to allocentric representation of local space. The strong connectivity of POR with the adjacent entorhinal cortex, and consequently the hippocampus, suggests that the development of these connections could support the postnatal development of contextual memory.

Genome-wide meta-analysis of iron status biomarkers and the effect of iron on all-cause mortality in HUNT.

Iron is essential for many biological processes, but iron levels must be tightly regulated to avoid harmful effects of both iron deficiency and overload. Here, we perform genome-wide association studies on four iron-related biomarkers (serum iron, serum ferritin, transferrin saturation, total iron-binding capacity) in the Trøndelag Health Study (HUNT), the Michigan Genomics Initiative (MGI), and the SardiNIA study, followed by their meta-analysis with publicly available summary statistics, analyzing up to 257,953 individuals. We identify 123 genetic loci associated with iron traits.

The genes controlling normal function of citrate and spermine secretion are lost in aggressive prostate cancer and prostate model systems.

High secretion of the metabolites citrate and spermine is a unique hallmark for normal prostate epithelial cells, and is reduced in aggressive prostate cancer. However, the identity of the genes controlling this biological process is mostly unknown. In this study, we have created a gene signature of 150 genes connected to citrate and spermine secretion in the prostate.

Outcomes in patients not conveyed by emergency medical services (EMS): a one-year prospective study.

Background: The decision to not convey patients has become common in emergency medical services worldwide. A substantial proportion (12-51%) of the patients seen by emergency medical services are not conveyed by those services. The practice of non-conveyance is a result of the increasing and changing demands on the acute care system.

Tofacitinib Downregulates TNF and Poly(I:C)-Dependent MHC-II Expression in the Colonic Epithelium.

Major Histocompatibility Complex (MHC)-I and -II genes are upregulated in intestinal epithelial cells (IECs) during active inflammatory bowel diseases (IBD), but little is known about how IBD-relevant pro-inflammatory signals and IBD drugs can regulate their expression. We have previously shown that the synthetic analog of double-stranded RNA (dsRNA) Polyinosinic:polycytidylic acid (Poly(I:C)), induces interferon stimulated genes (ISGs) in colon organoids (colonoids). These ISGs may be involved in the induction of antigen presentation.