Role of interleukin-4 receptor α polymorphism in patients with asthma and its correlation with asthma severity.

Asthma is a heterogeneous disease characterized by chronic airway inflammation. It is defined by the history of respiratory symptoms such as wheeze, shortness of breath, chest tightness, and cough that vary over time and intensity, together with variable expiratory airflow limitation. A personal history or a family history of allergy is the factor most strongly associated with the development of asthma.

Ionized Plasma Jet Therapy in Removal of Dermatosis Papulosa Nigra.

Background: Dermatosis papulosa nigra (DPN) presents as benign skin growths, predominantly affecting women and often commencing during adolescence. Treatment is sought due to its cosmetic impact, with available modalities often posing risks of scarring and pigmentary changes.

Materials & Methods: This study investigates the efficacy of ionized plasma jet therapy (IPJT) in ten DPN patients at a tertiary care hospital in central India.

Association of Hyperlipidemia and Hyperglycemia With Cognitive Function in Type 2 Diabetes: A Cross-Sectional Analysis.

Introduction Cognitive impairment is increasingly recognized as a significant health concern, particularly in the early stages of diabetes. The type and severity of cognitive deficits may vary with the duration of diabetes and the effectiveness of glucose management. Complications associated with metabolic syndrome may exacerbate these cognitive declines.

Morphea and Extragenital Lichen Sclerosus Et Atrophicus Overlap.

Lichen sclerosus et atrophicus (LSA) is a chronic inflammatory condition that affects mainly the genital regions but can occur extragenitally. Extragenital LSA occurs far less often than the genitally located variety and in most cases has been reported in females. A 36-year-old male engineer presented with chronic itchy lesions on the right forearm for more than a year's duration.

Gestational diabetes mellitus - Neonatal and maternal outcomes in women treated with insulin or diet: A propensity matched analysis.

Aims: Pregnant women worldwide face the risk of developing gestational diabetes mellitus (GDM), if left untreated, can cause complications. The study explores factors influencing the choice between diet control and insulin therapy for pregnant women with GDM. It aims to understand how these choices impact maternal and neonatal outcomes.

Ketamine Impact on Kidney Health.

Ketamine-induced uropathy (KIU) is a serious consequence of chronic ketamine abuse, presenting with complex renal and urinary symptoms. This study describes a 34-year-old female with a history of chronic ketamine abuse, resulting in stage 3 chronic kidney disease (CKD) and severe urological complications. Despite discontinuing ketamine use five years ago, she remains dependent on ureteral stents due to recurrent hydronephrosis and ureteral obstruction.

Study of Otorhinolaryngological Manifestations in Symptomatic COVID-19-Positive Patients at Tertiary Health Care Hospital: A Cross-sectional Study.

 The coronavirus disease 2019 (COVID-19), also referred to as the 2019 novel coronavirus, is caused by a single-stranded positive-sense RNA virus. This infectious agent spreads through respiratory routes, primarily utilizing aerosols. In our study, we shed light on ear, nose, and throat (ENT) manifestations, which can be considered as prognostic clinical biomarkers to reduce forthcoming complications among such critically ill patients.

Artificial Intelligence in Dry Eye Disease: A Narrative Review.

Dry eye disease (DED) is a multifactorial condition affecting millions worldwide, characterized by discomfort, visual disturbance, and potential damage to the ocular surface. The complexity of its diagnosis and management, driven by the diversity of symptoms and underlying causes, presents significant challenges to clinicians. Artificial intelligence (AI) has emerged as a transformative tool in healthcare, offering potential solutions to these challenges through its data analysis, pattern recognition, and predictive modeling capabilities.

Intracholecystic Papillary Neoplasm: A Rare Case Report.

Intracholecystic papillary neoplasm (ICPN) is a mass-forming, noninvasive epithelial premalignant neoplasm arising from the gallbladder mucosal lining and projecting into the lumen of the gallbladder. It is potentially fatal and if left untreated can progress to invasive gallbladder carcinoma. Incidentally ICPN is found on imaging or during postoperative histological evaluation and is likely to be missed preoperatively.

"The feedback dilemma"-provider and learner perspectives regarding the barriers and facilitators for giving and receiving feedback in medical education: A parallel mixed methods approach.

Background: Learning in medical education involves a multitude of practical tasks and skills that are amenable to feedback provision. Though passive feedback is given, there is a consistent gap in feedback provision and its receipt. This study aims to assess provider perspectives on feedback and learner attributes influencing the receipt of feedback in medical educational settings.

Comparison of the Effectiveness of Platelet-Rich Plasma Injection Versus Plantar-Specific Calf Stretching Exercises in Patients With Plantar Fasciitis: A Randomized Controlled Trial.

Background Plantar fasciitis is a common foot condition with multifactorial etiology. It is the most frequent cause of heel pain and has been categorized as an overuse syndrome. A clinical examination and history are crucial for diagnosis.

Anterior Cortical Impingement With 240 mm Cephalo-Medullary Nail (PFN and PFNA-2) in Intertrochanteric Femur Fracture Fixation in the Indian Population: A Problem Statement.

Trochanteric fractures are common in the elderly population, and their incidence increases twice every decade after age 50. Intramural fixation has achieved good clinical efficacy in the treatment of unstable trochanteric fractures, but there have been complications reported in the literature in the Asian population. Most complications arise from a mismatch between the increase in the anterior femoral bow with advancing age and the proximal femoral nails (PFN) on the market, which still have straight designs on the sagittal plane.

The Management of Complex Knee Deformity Using Ortho-SUV: A Case Study.

Lower limb deformities are debilitating and affect the function of the lower limb and the social life of the patient. The deformities around the knee joint might be a combination of multiple deformities in various planes including coronal, sagittal, or rotational and may be present in both the femur and the tibia. We present a case of a 19-year-old female with complex deformity around the left knee joint involving both the femur and the tibia with shortening.

Antenatal Diagnosis of Complete Annular Pancreas With Postnatal Surgical Follow-Up: A Case Report.

Annular pancreas is a rare congenital disorder, which is characterized by partial or complete pancreatic tissue surrounding the second part of the duodenum. It can be diagnosed antenatally on ultrasound. We are reporting a case where a double bubble sign on an antenatal scan was seen, which was followed up after the delivery of the baby, and radiography also confirmed the findings.

Seroprevalence and Seroconversion of Hepatitis B and C Viruses in Patients Undergoing Hemodialysis: A Cross-sectional Study.

Introduction: Among hemodialysis patients, hepatitis B virus (HBV) and hepatitis C virus (HCV) infections contribute significantly to mortality and morbidity. Infection with these hepatotropic viruses in hemodialysis patients is due to their increased contact with blood and its derivatives. Additionally, not following the proper protocol for infection control, contaminated devices, and untrained personnel contribute to the nosocomial transmission of these infections.

Functional Outcome of Forearm Fractures Managed With Screw Nails vs. Dynamic Compression Plates: A Prospective Study.

Background Fractures of the forearm are very frequently encountered in day-to-day practice. These fractures have a bimodal age distribution. The forearm fractures are considered intra-articular and need absolute stability for adequate healing.

Staged Limb Reconstruction Using Ilizarov Fixator in an Infected Tibia Nonunion: A Case Report.

Road traffic accidents are responsible for most lower limb compound fractures. Such fractures have to be treated immediately with utmost care and precision. Patients are sometimes inadequately treated with traditional practices which causes further disability to the patient and makes it more difficult for the orthopedic surgeon.

Diagnostic Efficacy of Ultrasound-Based International Ovarian Tumor Analysis Simple Rules and Assessment of the Different Neoplasias in the Adnexa Model in Malignancy Prediction Among Women With Adnexal Masses: A Systematic Review.

Transvaginal ultrasonography (USG) is most commonly used before surgery to accurately diagnose benign and malignant ovarian masses for effective treatment, avoid unnecessary interventions, improve the prognosis of patients, and preserve fertility in patients with benign tumors. Therefore, the objective of the present systematic review was to assess the diagnostic efficacy of ultrasound-based International Ovarian Tumor Analysis (IOTA) Simple Rules (SR) and Assessment of Different NEoplasias in the adneXa (ADNEX) model in predicting malignancy among women with adnexal masses. A systematic literature search was carried out on electronic databases consisting of Science Direct, PubMed, and Google Scholar.