2 results match your criteria: "NJSC Karaganda University Named after Y.A. Buketov[Affiliation]"
Methods of Analysis and Identification of Betulin and Its Derivatives.
Molecules
August 2023
Department of Organic Chemistry and Polymers, Chemistry Faculty, NJSC Karaganda University Named after Y.A. Buketov, Karaganda 100024, Kazakhstan.
This scientific work presents practical and theoretical material on the methods of analysis and identification of betulin and its key derivatives. The properties of betulin and its derivatives, which are determined by the structural features of this class of compounds and their tendency to form dimers, polymorphism and isomerization, are considered. This article outlines ways to improve not only the bioavailability but also the solubility of triterpenoids, as well as any hydrophobic drug substances, through chemical transformations by introducing various functional groups, such as carboxyl, hydroxyl, amino, phosphate/phosphonate and carbonyl.
View Article and Find Full Text PDFMethods of Betulin Extraction from Birch Bark.
Molecules
June 2022
Department of Chemistry and Chemical Technologies, NJSC Karaganda Technical University named after Abylkas Saginov, Karaganda 100027, Kazakhstan.
Article Synopsis
- - Betulin, a key triterpenoid from lupan series, has notable pharmacological properties including antibacterial, antiviral, antitumor, and hypolipidemic activities, making it valuable for medical and veterinary applications.
- - To utilize betulin effectively, efficient extraction methods are needed from birch bark waste, leading to a discussion on various techniques like vacuum sublimation, pyrolysis, supercritical extraction, and organic solvent extraction.
- - The review also explores the innovative microwave activation method on an endemic Kyrgyz birch species, highlighting its potential for isolating betulin in higher quantities.