58 results match your criteria: "NJSC "Astana Medical University[Affiliation]"
Iran J Public Health
March 2023
Department of Public Health and Management, NJSC "Astana Medical University", Astana, Kazakhstan.
Background: Chronic hepatitis B virus (CHB) infection is one of the most common liver infections worldwide. Approximately 240 million patients are diagnosed with CHB. The objective of this meta-analysis was to identify the effect of CHB on the affected patients' health-related quality of life and compare with the control group.
View Article and Find Full Text PDFGinekol Pol
March 2023
Clinical Academic Department of Women's Health, University Medical Center, Astana, Kazakhstan, Kazakhstan.
Objectives: The purpose of this study was to compare the use of unilateral apical sling versus laparoscopic sacrocolpopexy in the treatment of the apical form of pelvic organ prolapse in women. M: aterial and methods:A prospective, single-center randomized trial included 100 patients who were alternately assigned to treatment. Each patient had a ≥ III stage of apical or anterior-apical prolapse determined by the POP-Q system.
View Article and Find Full Text PDFMolecules
February 2023
Food Science and Technology Program, Department of Life Sciences, BNU-HKBU United International College, Zhuhai 519087, China.
The renaissance of research into natural products has unequivocally and paradigmatically shifted our knowledge about the significant role of natural products in cancer chemoprevention. Bufalin is a pharmacologically active molecule isolated from the skin of the toad or . Bufalin has characteristically unique properties to regulate multiple molecular targets and can be used to harness multi-targeted therapeutic regimes against different cancers.
View Article and Find Full Text PDFHealthcare (Basel)
March 2023
Council for Nutritional and Environmental Medicine, 8610 Mo i Rana, Norway.
Drunk driving is an important risk factor significantly contributing to traffic accidents and their associated lethality. This meta-analysis of observational studies aims to provide the estimates of drunk driving prevalence in non-lethally injured motor vehicle drivers in relation to the world region, blood alcohol concentration (BAC), and quality of the primary study. A systematic search for observational studies that examined the prevalence of drunk driving in injured drivers was performed, and 17 studies comprising 232,198 drivers were included in the pooled analysis.
View Article and Find Full Text PDFGeorgian Med News
January 2023
NJSC "Astana Medical University", Kazakhstan.
Given the difficulties of diagnosis, the absence of a typical clinical picture of myelodysplastic syndrome accompanied by cytopenia, a high risk of transformation into acute myeloid leukemia, discussion of the formation, terminology, pathogenesis, classification, clinical course and principles of management of this group of tumor diseases is very relevant. The review article discusses the issues of terminology, pathogenesis, classification and diagnosis of myelodysplastic syndrome (MDS), as well as the principles of management of this category of patients. Due to the absence of a typical clinical picture of MDS, in order to exclude other diseases accompanied by cytopenia, not only routine hematological examination methods are necessary, but also a mandatory cytogenetic examination of the bone marrow.
View Article and Find Full Text PDFGeorgian Med News
January 2023
5Clinical Diagnostic Department of the Almaty Cardiological Center, Kazakhstan.
In terms of morbidity and mortality, cardiovascular illnesses are the main cause of death worldwide. Half of all noncommunicable diseases on the earth are caused by them. Due to the steadily rising mortality rates from circulatory diseases in Kazakhstan, our region was identified as having a high cardiovascular risk in 2021 when the updated Score 2 (Systematic COronary Risk Evaluation) scale was developed.
View Article and Find Full Text PDFJ Clin Med
January 2023
Department of Biomedical Sciences, School of Medicine, Nazarbayev University, Astana 010000, Kazakhstan.
Background: Recurrent pregnancy loss (RPL) is associated with increased incidence and severity of depression, anxiety, and stress, and screening for these comorbidities following miscarriages is beneficial for women with RPL who are planning future pregnancies. This study aims to investigate depression, anxiety, and stress among Kazakhstani women with RPL. Methods: This was a case−control study involving 70 women with confirmed RPL and 78 ethnically matched control women.
View Article and Find Full Text PDFMed J Islam Repub Iran
December 2022
Department of Internal Medicine, Karaganda Medical University, Karaganda, Kazakhstan.
The article reviews the literature data on various somatic and mental pathologies, which are comorbid processes with similar pathophysiological, genetic and neurochemical mechanisms. The psychosomatic manifestations of cardiovascular diseases and coronavirus disease (COVID-19) are considered. Particular attention is paid to post-traumatic stress disorder of participants in local wars.
View Article and Find Full Text PDFMolecules
December 2022
Al-Farabi Kazakh National University, 71 al-Farabi Ave, Almaty 050040, Kazakhstan.
The pursual of novel anticancer molecules from natural sources has gained worthwhile appreciation, and a significant fraction of conceptual knowledge has revolutionized our understanding about heterogeneous nature of cancer. Betulinic acid has fascinated interdisciplinary researchers due to its tremendous pharmacological properties. Ground-breaking discoveries have unraveled previously unprecedented empirical proof-of-concept about momentous chemopreventive role of betulinic acid against carcinogenesis and metastasis.
View Article and Find Full Text PDFActa Inform Med
December 2022
Department of Department of Forensic Medicine; NJSC. Astana Medical University, Astana city, Kazakhstan.
Background: An important global public health problem in many economically developed countries, in particular in Kazakhstan, is the leading cause of morbidity and mortality from cardiovascular disease (CVD), both in urban and rural areas.
Objective: This study aims to develop the design of a mobile application for smartphones for cardiac patients, taking into account the specifics of outpatient care.
Methods: This methodological study includes identified educational and prevention content for CVD patients to develop an education and monitoring tool using a smartphone app.
Vaccines (Basel)
November 2022
Department of Biomedical Sciences, School of Medicine, Nazarbayev University, Astana 010000, Kazakhstan.
Immunization is the most successful method in preventing and controlling infectious diseases, which has helped saving millions of lives worldwide. The discovery of the human papillomavirus (HPV) infection being associated with a variety of benign conditions and cancers has driven the development of prophylactic HPV vaccines. Currently, four HPV vaccines are available on the pharmaceutical market: Cervarix, Gardasil, Gardasil-9, and the recently developed Cecolin.
View Article and Find Full Text PDFIran J Public Health
May 2022
Department of Public Health and Management, NJSC "Astana Medical University», Nur-Sultan, Kazakhstan.
Georgian Med News
November 2022
NJSC "Astana Medical University", Nur-Sultan, Kazakhstan.
The article deals with the problem of the clinical and functional relationship between the state of the thyroid gland in women of menopausal age and the components of the metabolic syndrome (MS). The purpose of the study: to assess the relationship between thyroid dysfunction and various components of MS in women of peri- and postmenopausal age. 80 menopausal women (mean age 55 years) were examined, of which 40 people with MS constituted the main group, and the comparison group - a similar number of women without MS.
View Article and Find Full Text PDFJ Laparoendosc Adv Surg Tech A
December 2022
Department of Pediatric Surgery and Urology, Wroclaw University of Medicine, Wroclaw, Poland.
The treatment of long-gap esophageal atresia (LGEA) remains an important issue for pediatric surgeons. There are several methods of treating LGEA with various advantages and disadvantages. Thoracoscopic esophageal elongation using internal traction sutures has been developed more recently.
View Article and Find Full Text PDFActa Inform Med
September 2022
S.D. Asfendiyarov Kazakh National Medical University, Almaty, Kazakhstan.
Background: Digitalization of healthcare led to the optimization of monitoring, diagnostics, and treatment of the range of disorders. Taking into account recent situation with COVID-19 pandemics, digital technologies allowed to improve management of viral infections via remote monitoring and diagnostics of infected patients. Up to date, various mobile health applications (apps) have been proposed, including apps for the patients diagnosed with cardiovascular pathologies.
View Article and Find Full Text PDFJ Radiat Res
August 2022
A. Tsyb Medical Radiological Research Center - Branch of the National Medical Research Radiological Center of the Ministry of Health of the Russian Federation, Koroleva Str., 4., Obninsk, Kaluga Region 2490036, Russian Federation.
Electron spin resonance (ESR) dosimetry was applied to human tooth enamel in order to obtain individual absorbed doses for victims of the Hiroshima bomb who lived in the 'black rain' area. The so-called 'black rain' fell in the form of precipitation on the western part of Hiroshima city and the northwestern suburbs within a few hours after the explosion of the atomic bomb on 6 August 1945, and exposed the population in this area. Only three tooth samples were collected from this area.
View Article and Find Full Text PDFGeorgian Med News
May 2022
NJSC "Astana Medical University", Ministry of Health of the Republic of Kazakhstan, Nur-Sultan, Kazakhstan.
In the world, stroke suffers 5.6-6 million people a year. Stroke deaths are predicted to rise to 6.
View Article and Find Full Text PDFPLoS One
August 2022
Department of Neurology, Ophthalmology, Otorhinolaryngology, NJSC "Semey Medical University", Semey, Republic of Kazakhstan.
Background: Vitiligo is one of the most common hypomelanoses, in which the destruction of functioning melanocytes causes depigmentation of the skin, hair and mucous membranes. The genes encrypting brain-derived neurotrophic factor (BDNF) and corticotropin releasing hormone (CRH) might be the conceivable contributors to the development of vitiligo. This study was aimed at investigation of the serum levels of BDNF and CRH as well as their selected single nucleotide polymorphisms (SNPs) in vitiligo patients in comparison with the healthy controls.
View Article and Find Full Text PDFScientificWorldJournal
May 2022
S.D. Asfendiyarov Kazakh National Medical University, Almaty, Kazakhstan.
Background: Viral hepatitis is a major burden for the healthcare system worldwide. Up to date, a comprehensive analysis of the prevalence of viral hepatitis in Kazakhstan and Central Asia has not been carried out yet. Our epidemiological study aimed at investigating the frequency and spread of viral hepatitis B, C, and D depending on age and sex in Kazakhstan (5-year period).
View Article and Find Full Text PDFIran J Public Health
October 2021
Department of Economics and Statistics, Udine University, Gorizia, Italy.
Int J Womens Health
February 2022
Department of Medicine, School of Medicine, Nazarbayev University, Nur-Sultan, Kazakhstan.
Purpose: Peripartum hysterectomy is a surgical procedure performed as a life-saving surgery to manage severe postpartum hemorrhage. The prevalence of peripartum hysterectomy in high-resource settings is relatively low. However, maternal mortality due to postpartum hemorrhage and after peripartum hysterectomy remains high in developing countries.
View Article and Find Full Text PDFGeorgian Med News
December 2020
NJSC "Astana Medical University", Department of Internal Medicine with a course of nephrology, hematology, allergology and immunology.
Primary myelofibrosis is a common disease from the group of Ph-negative myeloproliferative diseases. The article presents modern data on the pathogenesis of Ph-negative myeloproliferative diseases, as well as diagnostic criteria, treatment tactics and prognosis factors for primary myelofibrosis. A clinical case of transformation of primary myelofibrosis into acute myeloid leukemia is described.
View Article and Find Full Text PDFInt J Telemed Appl
December 2020
S.D. Asfendiyarov Kazakh National Medical University, Almaty, Kazakhstan.
Background: The implementation of medical digital technologies can provide better accessibility and flexibility of healthcare for the public. It encompasses the availability of open information on the health, treatment, complications, and recent progress on biomedical research. At present, even in low-income countries, diagnostic and medical services are becoming more accessible and available.
View Article and Find Full Text PDFMedicina (Kaunas)
November 2020
NJSC "Astana Medical University", Nur-Sultan 010000, Kazakhstan.
The aim of the study was to scrutinize the ability of epsilon-aminocaproic acid (EACA) to prevent radiation-induced damage to human cells. Human peripheral blood mononuclear cells (PBMCs) were exposed to ionizing radiation at three low doses (22.62 mGy, 45.
View Article and Find Full Text PDFRadiat Environ Biophys
November 2020
Ural Research Center for Radiation Medicine, Vorovsky Str. 68A, 454076, Chelyabinsk, Russia.
Radiation monitoring is an important radiation safety measure implemented at the hydrometallurgical plant of the Stepnogorsk mining and chemical combine (HMP SMCC, Republic of Kazakhstan). Follow-up of the workers and their regular medical examinations has laid the basis to create a cohort with the potential to be used in radiation epidemiology. The aim of current pilot study was to analyze the dose forming factors for workers of HMP SMCC.
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