55 results match your criteria: "NICU "V. Buzzi" Children's Hospital[Affiliation]"
J Pediatr
October 2024
Division of Neonatology, Department of Pediatrics and Adolescent Medicine, Medical University of Graz, Graz, Austria; Research Unit for Neonatal Micro- and Macrocirculation, Department of Pediatrics and Adolescent Medicine, Medical University of Graz, Graz, Austria. Electronic address:
Pediatr Neurol
June 2024
Pediatric Radiology and Neuroradiology Unit, V. Buzzi Children's Hospital, Milan, Italy.
Background: The prognostic relevance of fetal/early postnatal magnetic resonance (MR) imaging (MRI) isolated "minor" lesions in congenital cytomegalovirus (CMV) infection is still unclear, because of the heterogeneity of previously reported case series. The aim of this study was to report the imaging and long-term clinical follow-up data on a relatively large cohort of infected fetuses.
Methods: Among 140 CMV-infected fetuses from a single-center 12-year-long fetal MRI database, cases that showed isolated "minor" lesions at MRI, mainly represented by polar temporal lesions, were selected.
Pathogens
March 2024
Department of Neonatology and Neonatal Intensive Care Unit, V. Buzzi Children's Hospital, 20154 Milan, Italy.
Coagulase-negative staphylococci (CoNS) are reportedly responsible for 50-60% of bloodstream infections in very preterm (<1500 g) infants in neonatal intensive care units (NICUs). is an increasingly prevalent pathogen in the neonatal setting, frequently causing central-line-associated bloodstream infections (CLABSIs) that can be difficult to eradicate. Central venous catheter (CVC) removal versus in situ treatment with CoNS CLABSIs is a controversial treatment strategy with no clear consensus.
View Article and Find Full Text PDFiScience
April 2024
Department of Biomedical and Clinical Sciences, Pediatric Clinical Research Center "Romeo and Enrica Invernizzi", University of Milan, 20157 Milan, Italy.
Pediatr Pulmonol
April 2024
Division of Neonatology, "V. Buzzi" Children's Hospital-ASST-FBF-Sacco, Milan, Italy.
Minerva Pediatr (Torino)
February 2024
Unit of Neonatal Intensive Care, V. Buzzi Children's Hospital, ASST-FBF-Sacco, Milan, Italy -
Background: Proper umbilical cord stump care during the first days of life (both in hospital and at home) should not be overlooked to prevent possible complications (e.g., purulent discharge, granulomas, or periumbilical erythema or omphalitis).
View Article and Find Full Text PDFMol Genet Genomic Med
January 2024
Laboratory of Medical Genetics, ASST Papa Giovanni XXIII, Bergamo, Italy.
Background: The recent guidelines suggest the use of genome-wide analyses, such as whole exome sequencing (WES), at the beginning of the diagnostic approach for cases with suspected genetic conditions. However, in many realities it still provides for the execution of a multi-step pathway, thus requiring several genetic tests to end the so-called 'diagnostic odyssey'.
Methods: We reported the results of GENE Project (Genomic analysis Evaluation NEtwork): a multicentre prospective cohort study on 125 paediatric outpatients with a suspected genetic disease in which we performed first-tier trio-WES, including exome-based copy number variation analysis, in parallel to a 'traditional approach' of two/three sequential genetic tests.
Early Hum Dev
August 2023
Newborn Services, John Radcliffe Hospital, Oxford University Hospital, Oxford, UK; Department of Paediatrics, Division of Medical Sciences, University of Oxford, Oxford, UK. Electronic address:
Infants <28 weeks' gestation in need of inflations at birth were recorded with Respiratory Function Monitor. Two devices were used for resuscitation. Peak Inspiratory Pressure spikes were visible in all inflations with GE Panda and in none with Neo-Puff.
View Article and Find Full Text PDFBMJ
January 2023
Centre for the Studies of Asphyxia and Resuscitation, Neonatal Research Unit, Royal Alexandra Hospital, Edmonton, AB, Canada.
Objective: To investigate whether monitoring of cerebral tissue oxygen saturation using near infrared spectroscopy in addition to routine monitoring combined with defined treatment guidelines during immediate transition and resuscitation increases survival without cerebral injury of premature infants compared with standard care alone.
Design: Multicentre, multinational, randomised controlled phase 3 trial.
Setting: 11 tertiary neonatal intensive care units in six countries in Europe and in Canada.
Lancet
February 2023
Nuffield Department of Women's & Reproductive Health, University of Oxford, Oxford, UK; Oxford Maternal and Perinatal Health Institute, Green Templeton College, University of Oxford, Oxford, UK; St George's University Hospitals NHS Foundation Trust, London, UK. Electronic address:
Background: In 2021, we showed an increased risk associated with COVID-19 in pregnancy. Since then, the SARS-CoV-2 virus has undergone genetic mutations. We aimed to examine the effects on maternal and perinatal outcomes of COVID-19 during pregnancy, and evaluate vaccine effectiveness, when omicron (B.
View Article and Find Full Text PDFPediatr Pulmonol
February 2023
NICU "V. Buzzi" Children's Hospital, ASST-FBF-Sacco, Milan, Italy.
Aim: To verify the added value of respiratory function monitor (RFM) to assess ventilation and the heart rate (HR) changes during stabilization of preterm infants.
Methods: Preterm infants <32 weeks' gestation, bradycardic at birth and in need for positive pressure ventilation (PPV) were included. The first 15 min of stabilization was monitored with RFM.
Front Pediatr
September 2022
Division of Neonatology, "V. Buzzi" Children's Hospital ASST-FBF-Sacco, Milan, Italy.
Objective: To investigate the relationship between the Neonatal Assessment Manual scorE (NAME) and newborns' clinical condition on a large number of infants. The NAME model was developed as an instrument to assess the infant's general conditions, especially in NICUs, by evaluating how the infant's body responds to an external stressor such as static touch. Previous studies, employing experienced assessors, showed good validity indices as well as high inter-rater reliability.
View Article and Find Full Text PDFAntibiotics (Basel)
August 2022
Neonatology and Neonatal Intensive Care Unit, V. Buzzi Children's Hospital, 20100 Milan, Italy.
Current neonatal early-onset sepsis (EOS) guidelines lack consensus. Recent studies suggest three different options for EOS risk assessment among infants born ≥35 wks gestational age (GA), leading to different behaviors in the sepsis workup and antibiotic administration. A broad disparity in clinical practice is found in Neonatal Units, with a large number of non-infected newborns evaluated and treated for EOS.
View Article and Find Full Text PDFFront Pediatr
September 2021
Division of Neonatology, Department of Pediatrics, "V. Buzzi" Children's Hospital, ASST-FBF-Sacco, Milan, Italy.
Despite clinical improvements in neonatal intensive care units (NICUs), prematurity keeps causing several comorbidities. To enhance the management of such conditions, in previous studies we devised the Neonatal Assessment Manual scorE (NAME) model, a structured touch-based assessment that aims to evaluate how newborns respond to gentle touch-based stimuli. The present study aimed to begin assessing the NAME interrater reliability and specific agreements.
View Article and Find Full Text PDFItal J Pediatr
October 2021
NICU, Department of Pediatrics, V. Buzzi Children's Hospital, ASST-FBF-Sacco, Milan, Italy.
Background: Neonatal hypoglycemia is a common disorder especially in at-risk infants and it can be associated with poor long-term neurological outcomes. Several therapeutic interventions are suggested, from the implementation of breastfeeding to the glucose intravenous administration. Oral dextrose gel massaged into the infant's inner cheek is a recent treatment option of asymptomatic hypoglycemia, after which oral feeding is encouraged.
View Article and Find Full Text PDFFront Psychiatry
September 2021
Child Neurology and Psychiatry Unit, IRCCS Mondino Foundation, Pavia, Italy.
The COVID-19 pandemic is a collective trauma that is threatening citizens' mental health resulting in increased emotional stress, reduced social support, and heightened risk for affective symptoms. The present study aimed to investigate the effects of antenatal pandemic-related emotional stress and perceived social support on the symptoms of depression and anxiety of mothers who were pregnant during the initial COVID-19 outbreak in northern Italy. A sample of 281 mothers was enrolled at eight maternity units in the first hotspot region of the COVID-19 outbreak in northern Italy.
View Article and Find Full Text PDFResuscitation
October 2021
Division of Neonatology, Department of Paediatrics, Leiden University Medical Centre, Leiden, the Netherlands. Electronic address:
Resuscitation
July 2021
Division of Neonatology, Medical University of Graz, Auenbruggerplatz 34/2, 8036 Graz, Austria; Research Unit of Cerebral Development and Oximetry, Medical University of Graz, Auenbruggerplatz 34/2, 8036 Graz, Austria. Electronic address:
Aim Of The Study: Analysis of the impact of bradycardia and hypoxemia on the course of cerebral and peripheral oxygenation parameters in preterm infants in need for respiratory support during foetal-to-neonatal transition.
Methods: The first 15 min after birth of 150 preterm neonates in need for respiratory support born at the Division of Neonatology, Graz (Austria) were analyzed. Infants were divided into different groups according to duration of bradycardia exposure (no Bradycardia, brief bradycardia <2 min, and prolonged bradycardia ≥2 min) and to systemic oxygen saturation (SpO) value at 5 min of life (<80% or ≥80%).
Pathogens
March 2021
Neonatal Intensive Care Unit, Medical and Surgical Department of Fetus, Newborn and Infant, "Bambino Gesù" Children's Hospital IRCCS, 00165 Rome, Italy.
Infections represent a serious health problem in neonates. Invasive infections (ICIs) are still a leading cause of mortality and morbidity in neonatal intensive care units (NICUs). Infants hospitalized in NICUs are at high risk of ICIs, because of several risk factors: broad spectrum antibiotic treatments, central catheters and other invasive devices, fungal colonization, and impaired immune responses.
View Article and Find Full Text PDFClin Neurophysiol
April 2021
Child Neuropsychiatric Unit, Neuroscience Section, Department of Medicine and Surgery, University of Parma, Italy.
The aim of this work is to establish inclusive guidelines on electroencephalography (EEG) applicable to all neonatal intensive care units (NICUs). Guidelines on ideal EEG monitoring for neonates are available, but there are significant barriers to their implementation in many centres around the world. These include barriers due to limited resources regarding the availability of equipment and technical and interpretive round-the-clock personnel.
View Article and Find Full Text PDFItal J Pediatr
March 2021
RAISE lab, Foundation COME Collaboration, Corso Europa 29 - 66054 Vasto (Italy), Pescara, Italy.
Background And Objectives: The Neonatal Assessment Manual scorE (NAME) was developed to assist in the clinical management of infants in the neonatal ward by assessing their body's compliance and homogeneity. The present study begins its validation process.
Methods: An expert panel of neonatal intensive care unit (NICU) professionals investigated the NAME face and content validity.
Pediatr Res
September 2021
Neonatal Intensive Care Unit, "V. Buzzi" Children's Hospital, ASST-FBF-Sacco, Milan, Italy.
Background: In preterm infants, InSurE (Intubation-Surfactant-Extubation) and LISA (less invasive surfactant administration) techniques allow for exogenous surfactant administration while reducing lung injury associated with mechanical ventilation. We compared the acute pulmonary response and lung deposition of surfactant by LISA and InSurE in surfactant-depleted adult rabbits.
Methods: Twenty-six spontaneously breathing surfactant-depleted adult rabbits (6-7 weeks old) with moderate RDS and managed with nasal continuous positive airway pressure were randomized to 3 groups: (1) 200 mg/kg of surfactant by InSurE; (2) 200 mg/kg of surfactant by LISA; (3) no surfactant treatment (Control).
Pediatr Pulmonol
February 2021
Neonatal Intensive Care Unit and Neonatology, "San Giovanni Calibita" Fatebenefratelli Hospital - Isola Tiberina, Rome, Italy.
Background: Although short binasal prongs (SBP) are the most common interface for noninvasive ventilation, the "double-inspiratory loop cannulas" (DILC) have recently been introduced into many neonatal intensive care units. DILC show advantages over SBP, including reduced nasal trauma and increased comfort. However, their higher intrinsic resistance may compromise ventilation.
View Article and Find Full Text PDFFront Neurosci
September 2020
Research and Assistance for Infants to Support Experience Lab, Foundation Center for Osteopathic Medicine Collaboration, Pescara, Italy.
Neonatal intensive care units (NICUs) greatly expand the use of technology. There is a need to accurately diagnose discomfort, pain, and complications, such as sepsis, mainly before they occur. While specific treatments are possible, they are often time-consuming, invasive, or painful, with detrimental effects for the development of the infant.
View Article and Find Full Text PDFEur J Pediatr
February 2021
Pediatric Intensive Care Unit, Department of Women's and Children's Health, University Hospital of Padua, Via Giustiniani 2, 35128, Padova, Italy.
Northern Italy has been the first European area affected by the COVID-19 pandemic and related social restrictive measures. We sought to evaluate the impact of the COVID-19 outbreak on PICU admissions in Northern Italy, using data from the Italian Network of Pediatric Intensive Care Units Registry. We included all patients admitted to 4 PICUs from 8-weeks-before to 8-weeks-after February 24, 2020, and those admitted in the same period in 2019.
View Article and Find Full Text PDF