Computational Analysis Reveals the Characteristics of Immune Cells in Glomerular and Tubulointerstitial Compartments in IgA Nephropathy Patients.

The commonalities and differences regarding immune states between glomerular and tubulointerstitial compartments of IgA nephropathy (IgAN) remains largely undetermined. We aim to perform bioinformatic analysis for providing a comprehensive insight into the characteristics of immune cells and associated molecular mechanisms in IgAN. We performed integrated bioinformatic analyses by using IgAN-related datasets from the Gene Expression Omnibus database.

Prevalence of long-term complications in inpatients with diabetes mellitus in China: a nationwide tertiary hospital-based study.

Introduction: There is absence of national data to estimate the prevalence of long-term diabetic complications among inpatients with diabetes in tertiary hospitals in China.

Research Design And Methods: Using the national Hospital Quality Monitoring System database, inpatients with type 1 diabetes mellitus (T1DM) and type 2 diabetes mellitus (T2DM) were identified by the International Classification of Diseases-10 code, and the temporal trends of microvascular and macrovascular complications 2013-2017 were calculated, and then the risk factors were analysed by multivariate regression analysis.

Results: A total of 92 413 inpatients with T1DM and 6 094 038 inpatients with T2DM were identified in 2013-2017.