New York State Climate Impacts Assessment Chapter 04: Buildings.

New York State has nearly 5.3 million buildings, and all of them are vulnerable in some way to the impacts of climate change. Understanding these impacts is critical, because risks to buildings not only threaten individual lives but also pose threats to community-level resilience.

New York State Climate Impacts Assessment Chapter 05: Ecosystems.

The people of New York have long benefited from the state's diversity of ecosystems, which range from coastal shorelines and wetlands to extensive forests and mountaintop alpine habitat, and from lakes and rivers to greenspaces in heavily populated urban areas. These ecosystems provide key services such as food, water, forest products, flood prevention, carbon storage, climate moderation, recreational opportunities, and other cultural services. This chapter examines how changes in climatic conditions across the state are affecting different types of ecosystems and the services they provide, and considers likely future impacts of projected climate change.

New York State Climate Impacts Assessment Chapter 03: Agriculture.

Agriculture is a vital industry in New York State, which ranks among the top-producing states for dairy, fruits, and several other commodities. As agriculture depends on the weather and specific climatic conditions, this sector faces extraordinary challenges as New York's climate changes. This chapter explores the many impacts of a changing climate on agriculture, the ways these impacts interact with other challenges that New York farmers and farmworkers face, and opportunities for the agriculture industry to adapt and build resilience.

New York State Climate Impacts Assessment Chapter 02: New York State's Changing Climate.

Many fundamental aspects of New York State's climate have already begun to change, and the changes are projected to continue-and in some cases, accelerate-throughout the 21st century. This chapter explores observed and projected changes in a variety of physical variables that relate directly to weather and climate, starting with average and extreme air temperature and proceeding to the associated effects on precipitation, extreme events, and core properties of New York's coastal and inland waters. These climate attributes and hazards lead to impacts throughout the eight sectors of this assessment.

Decoding Dystonia in Autoimmune Disorders: A Scoping Review.

Background: Dystonia is a common hyperkinetic movement disorder observed in various genetic, infective, drug-induced, and autoimmune disorders. Autoimmune disorders can present with isolated or combined acute or subacute dystonia. The pattern and approach to dystonia in autoimmune disorders are poorly described and have never been established in a structured manner.

Is Artificial Intelligence the Future of Radiology? Accuracy of ChatGPT in Radiologic Diagnosis of Upper Extremity Bony Pathology.

Background: Artificial intelligence (AI) is a promising tool to aid in diagnostic accuracy and patient communication. Prior literature has shown that ChatGPT answers medical questions and can accurately diagnose surgical conditions. The purpose of this study was to determine the accuracy of ChatGPT 4.

Bariatric surgery does not affect kidney stone disease.

Background: numerous epidemiological studies demonstrate the correlation between obesity and urolithiasis. Bariatric surgery is effective in significant weight loss, reducing mortality rates, and lowering the incidence of obesity-related comorbidities. However, it may be associated with long-term complications such as urolithiasis, with an estimated increase of 7.

Pediatric Obesity's Effect on Open and Laparoscopic Appendectomy Outcomes.

 Pediatric obesity is a common comorbid condition that may complicate pediatric surgeries, such as appendectomy. Prior research on the consequences of obesity on pediatric appendectomy outcomes have been limited by small-sample sizes and pooled analyses that do not distinguish the effects of surgical approach. Associations between surgical approach, pediatric obesity, and postoperative appendectomy outcomes thus remain unclear.

The Efficiency of Antiosteoporosis Medicine after Intertrochanteric Fracture Surgery: A Retrospective Study of Refracture Rate, Function Recovery, Complications, and Mortality in the Chinese Elderly Population.

 This research aimed to discern the effects of antiosteoporosis medication on postoperative functional recovery, refracture incidence, complications, and mortality in geriatric patients with intertrochanteric fractures.  A retrospective study was conducted on 250 patients aged 65 years and above who underwent surgery for intertrochanteric fractures between January 2013 and December 2014. Intertrochanteric fracture is diagnosed with International Classification of Diseases 10th Revision code (S72.

Synthetic lethal strategies for the development of cancer therapeutics.

Synthetic lethality is a genetic phenomenon whereby the simultaneous presence of two different genetic alterations impairs cellular viability. Importantly, targeting synthetic lethal interactions offers potential therapeutic strategies for cancers with alterations in pathways that might otherwise be considered undruggable. High-throughput screening methods based on modern CRISPR-Cas9 technologies have emerged and become crucial for identifying novel synthetic lethal interactions with the potential for translation into biologically rational cancer therapeutic strategies as well as associated predictive biomarkers of response capable of guiding patient selection.

Interplay of elasticity and flow velocity on gorgonian feeding and implications for bioinspired design.

Evidence shows that gorgonians are more resistant to ocean acidification and rising temperatures than hard corals and are vital to reef health and the reestablishment of disrupted coral reef communities. Gorgonian coral's resilience and its diversity of morphology and environment make it well-suited as a model organism for bioinspired design applied to particle capture. We focus on flow near the polyps, using an updated form of the immersed boundary method to model the fluid-structure interaction of the flexible polyps and the surrounding ocean water.

Identification of Whey Protein-Derived Anti-Obesity Peptides Through 3T3-L1 Adipocyte Differentiation Assay.

Whey proteins are a rich source of bioactive peptides. Whey protein hydrolysate (WPH) can effectively improve metabolic syndrome and reduce the risk of obesity. Bioactive peptides isolated from various food sources exhibit anti-obesity effects.

Molecular detection and quantification of canine parvovirus 2 using a fast and sensitive SYBR green-based quantitative polymerase chain reaction assay in dogs affected with gastroenteritis.

Background And Aim: Viral gastroenteritis in canines is primarily caused by the canine parvovirus 2 (CPV-2). Infections by this virus can cause severe consequences in dogs, such as fever, vomiting, diarrhea, septicemia, systemic inflammation, and immunosuppression. Therefore, the mortality rate of persistent infections caused by this virus is significantly high.

Early Levodopa-Induced Motor Complications in RAB39B X-Linked Parkinsonism.

Background: While levodopa may benefit some patients with monogenic Parkinson's Disease and parkinsonism, others may exhibit aberrant responses earlier after exposure. Reporting treatment responses in rare genetic parkinsonism will help tailor therapeutic approaches to specific patients subpopulations.

Case Report: We report the therapeutic response in a patient with X-linked parkinsonism, who exhibited motor and non-motor complications within a few months of Levodopa.

Comparison of 1-Year Outcome Among Different Low Dosage Triamcinolone Acetonide Injections for Trigger Finger.

Background: This study was designed to compare the 1-year outcome among the groups with different low-dosage triamcinolone acetonide (TA) injections for trigger finger.

Methods: In the study period, trigger digits were initially injected with 2, 4, or 8 mg TA. We checked whether they had a second injection or surgery during the following year by either patients' revisit or telephone interview.

Effects of Postoperative Oral Corticosteroids on Infection Rates in Upper Extremity Surgery.

Background: The recent trend in administering postoperative oral corticosteroids has proven effective in alleviating pain and improving surgical outcomes for hand and upper extremity procedures. However, concerns persist regarding potential infection risks despite a lack of supporting evidence in the current literature. We propose that a 6-day regimen of low-dose postoperative oral corticosteroids is safe and does not increase the likelihood of surgical site infections (SSIs) in adult upper extremity surgeries.

How Rice Responds to Temperature Changes and Defeats Heat Stress.

With the intensification of the greenhouse effect, a series of natural phenomena, such as global warming, are gradually recognized; when the ambient temperature increases to the extent that it causes heat stress in plants, agricultural production will inevitably be affected. Therefore, several issues associated with heat stress in crops urgently need to be solved. Rice is one of the momentous food crops for humans, widely planted in tropical and subtropical monsoon regions.

CD spectra reveal the state of G-quadruplexes and i-motifs in repeated and other DNA sequences.

The B-DNA of the genome contains numerous sequences that can form various noncanonical structures including G-quadruplex (G4), formed by two or more stacks of four guanine residues in a plane, and intercalating motif (i-motif [iM]) formed by alternately arranged C-C pairs. One of the easy yet sensitive methods to study G4s and iMs is circular dichroism (CD) spectroscopy, which generates characteristic G4 and iM peaks. We have analyzed and compared the effects of various environmental factors including pH, buffer composition, temperature, flanking sequences, complimentary DNA strands, and single-stranded DNA binding protein (SSB) on the CD patterns of G4s and iMs generated by two groups of DNA molecules, one containing tandem repeats of GGGGCC and CCCCGG from the C9ORF72 gene associated with amyotrophic lateral sclerosis and frontotemporal dementia, and the second containing polyG/polyC clusters from oncogene promoter-proximal regions without such tandem repeats.