[Clinical course and outcomes of chronic viral hepatitis D in patients from Republic of Tuva as endemic region].

Introduction: Hepatitis D (delta, 5) is caused by an RNA virus (hepatitis D virus, HDV) from genus Deltavirus, and is the most severe and difficult to treat disease among both viral hepatitis and infectious diseases in general. The development of HDV infection in the host organism is possible only in the presence of hepatitis B virus (HBV). Coinfection with HBV and HDV is associated with a more rapid progression of chronic viral hepatitis (CVH) to liver cirrhosis (LC) and an unfavorable outcome in comparison with HBV monoinfection.

Contrast Agents Based on Iron Oxide Nanoparticles for Clinical Magnetic Resonance Imaging.

Magnetic resonance imaging (MRI) is one of the most perspective methods of noninvasive visualization in medicine, and use of contrast agents significantly its potentialities extends. Iron oxide nanoparticles are promising contrast agents, but in fact all the data on their efficiency were obtained in high-field tomographs for experimental animals. We studied the possibility of using magnetic nanoparticles for MRI visualization of rat brain glioblastoma at the most common clinical field 1.

Pediatric airway tumors: A report from the International Network of Pediatric Airway Teams (INPAT).

Objective: Primary tracheobronchial tumors (PTTs) are rare heterogeneous lesions arising from any part of the tracheobronchial tree. Nonspecific symptoms may lead to delayed diagnosis that requires more aggressive surgical treatment. An analysis of cases collected by the International Network of Pediatric Airway Team was undertaken to ensure proper insight into the behavior and management of PTTs.

Magnetic Resonance Imaging of Brain Involvement in Dogs Using Paramagnetic Contrast Enhancement with Mn(II)-DCTA P.

Experimental study of a new paramagnetic complex Mn-DCTA is carried out. The complex (0.5 M manganese(II) solution with trans-1,2-diamine cyclohexane-N,N,N',N'-tetraacetic acid; Cyclomang) was used for contrast magnetic resonance imaging visualization of CNS involvement in dogs with severe forms of Babesia canis infection.

[Vacuum-therapy for complicated anterior abdominal wall wounds and intestinal fistulas in children].

Aim: To present results of VAC application in children with complicated wounds of anterior abdominal wall combined with intestinal and/or biliary fistulas.

Material And Methods: For the last 7 years 8 patients aged from 1.5 months to 15 years with infected postoperative wounds of anterior abdominal wall complicated by intestinal fistulas (6), biliary and intestinal fistulas (1) and biliary fistula (1) have been treated at the surgical department №2 of Russian Children's Clinical Hospital.

[Thoracoscopic operations for neurogenic tumors in children].

Aim: To present an overall experience of endoscopic operations in children with neurogenic tumors in two medical institutions.

Material And Methods: Thoracoscopic excision of tumors was performed in 19 children aged 1 month-7.5 years (mean 1.

[Accelerated postoperative rehabilitation: multidisciplinary issue (Part 1)].

Aim: To discuss the main aspects of multimodal method of accelerated postoperative rehabilitation (fast track surgery).

Material And Methods: The program of accelerated rehabilitation consists of minimization of surgical treatment's stressful influence on patient's organism in perioperative period. The method implies use of efficient preoperative management, minimally invasive operations, regional anesthesia and short-acting anesthetics, early postoperative rehabilitation.

[Sliding traсheal plasty in children under extracorporeal membrane oxygenation (first experience in Russia)].

Aim: To improve the results of surgical treatment of children with extended tracheal stenosis.

Material And Methods: Since 2013 slidingtraсheal plasty under extracorporeal membrane oxygenation was performed in 4 children aged 1 year 2 months - 4.5 years with extended tracheal stenosis in Children's City Clinical Hospital №13.

[Immunological aspects in spleen ruptures surgery due to closed abdominal trauma].

The remote results of immunity investigation in 30 patients after organ-preserving surgery and in 30 patients after splenectomy forspleen rupture are presented in the article. Indexes of cellular and humoral immunity were normal and life quality did not differ from that in healthy individuals after organ-preserving operations with splenic artery ligation. Splenectomy leads to deterioration of life quality and disorders in cellular immunity including decrease of T-helpers/inductors cells (CD4), immunoregulatory index (CD3/CD4) and general number of T-lymphocytes (CD3) in some cases on background of compensatory increase of normal killers (CD16).

[Accelerated postoperative rehabilitation: multidisciplinary issue. Part 2].

Aim: To discuss the main aspects of multimodal method of accelerated postoperative rehabilitation (fast track surgery).

Material And Methods: The program of accelerated rehabilitation consists of minimization of surgical treatment's stressful influence on patient's organism in all stages of perioperative period. The method implies use of efficient preoperative management, minimally invasive operations, regional anesthesia and short-acting anesthetics, early postoperative rehabilitation.

Profile of microRNA expression in brain tumors of different malignancy.

The expression profiles of 10 mature microRNA (7, 10a, 17, 20a, 21, 23a, 26a, 137, 222) in biopsy specimens of gliomas of different malignancy were studied by the real time PCR with SYBR Green I fluorescent stain. The expression of microRNA-21 increased significantly, while that of microRNA-137 decreased, depending on the tumor malignancy. The expression of microRNA-9, -17, -20a, -23a, -26a was significantly higher, while that of microRNA-7 lower in the tumor vs.

Histoenzymology of the contractile myocardium in experimental pulmonary stenosis.

Metabolism of contractile cardiomyocyte in experimental pulmonary stenosis complicated or not complicated by heart failure was studied by histochemical methods. In pulmonary stenosis not complicated by heart failure, intensification of glycolysis, more intense oxidation of free fatty acids and their metabolites, and acceleration of the citric acid cycle were found in the contractile cardiomyocytes. In pulmonary stenosis complicated by heart failure, glycogen content in the myocardium was sharply decreased.