Myelofibrosis: best practices, controversies and 2019 update.

: Recent advances in the prognostic scheme and treatment of primary and secondary myelofibrosis (MF) have resulted in an overwhelming amount of clinical information to assimilate. The authors believe a comprehensive review that summarizes the most recent published literature, could serve as guidelines for the practicing hematologist.: The authors provide a summary of landmark articles regarding epidemiology, symptoms, and pathogenesis of disease.