203 results match your criteria: "Mycobacterium Marinum Infection of the Skin"

Introduction: Mycobacterium marinum is a well-known pathogenic non-tuberculous mycobacterium for skin and soft tissue infections. Infection, often presenting as superficial lesions, is seen after exposure of skin abrasions to contaminated water or infected fish and is known as "swimming pool" or "fish tank" granuloma. This study reported a case of M.

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To investigate differences in the clinical features of patients with sporotrichosis and cutaneous Mycobacterium marinum infection, and develop a prediction model for the initial identification. A total of 121 patients were selected based on the results from etiological culture. Logistic regression analyses were employed to identify the most valuable variables.

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Rationale: Mycobacterium marinum (M marinum), a slow-growing nontuberculous mycobacterium (NTM), is widely distributed in aquatic environments. It is a well-known cutaneous pathogen, which causes sporotrichosis-like lesions.

Patient Concerns: In this report, we describe 2 cases of subcutaneous M marinum infection.

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[Sporotrichoid lymphocutaneous Mycobacterium marinum infection].

Dermatologie (Heidelb)

October 2024

Klinik und Poliklinik für Dermatologie und Allergologie, Klinikum der Universität München, LMU München, Frauenlobstr. 9-11, 80337, München, Deutschland.

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[Skin disease caused by :a case report].

Zhonghua Jie He He Hu Xi Za Zhi

September 2024

Department of Infectious Diseases, Linyi People's Hospital, Linyi 276000, China.

Article Synopsis
  • The article discusses a case where a 54-year-old man developed skin lesions after being stung by a marine fish, ultimately leading to an infection.
  • Advances in molecular detection technology, particularly NGS (next-generation sequencing), are helping improve the diagnosis rates of skin diseases.
  • The patient was treated with a combination of antibiotics (rifampicin, clarithromycin, and minocycline), leading to the successful reduction and eventual disappearance of his lesions.
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A Series of 35 Cutaneous Infections Caused by in Han Chinese Population.

J Trop Med

August 2023

Shandong Provincial Hospital for Skin Diseases & Shandong Provincial Institute of Dermatology and Venereology, Shandong First Medical University and Shandong Academy of Medical Sciences, Jinan, China.

Article Synopsis
  • - This study examined cutaneous infections, focusing on how treatment times varied for patients with different skin lesions, specifically looking at those receiving single versus multiple drug therapies.
  • - Researchers analyzed data from 35 patients, exploring their clinical characteristics and immune responses by comparing them to a group of healthy controls.
  • - The findings indicated that a majority of patients had specific lesion patterns and that certain immune markers were significantly elevated in patients, suggesting potential trends that may require further investigation despite the small sample size.
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Article Synopsis
  • - Mycobacterium marinum is a type of non-tuberculous mycobacterium commonly found in non-chlorinated water and is recognized as a pathogen for fish; in humans, it can cause skin infections and sometimes more serious conditions.
  • - The text discusses four cases of cutaneous infections caused by M. marinum that were analyzed in a specialized medical center.
  • - It emphasizes the importance of accurate diagnosis, the need for healthcare providers to maintain a high level of suspicion when encountering these infections, and reviews the treatment options available.
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Article Synopsis
  • The study addresses the challenge of chronic skin infections by developing a rapid PCR-based detection method that outperforms traditional diagnostic techniques.
  • It involved designing four specific primer pairs and validating their effectiveness through tests on various samples, including clinical isolates and animal models.
  • Results showed 100% sensitivity and specificity in detecting the target organism in different tissue types, highlighting the reliability of this new detection system for clinical application.
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ALA-PDT shortens the course of antibiotic therapy for skin infection caused by Mycobacterium marinum.

Photodiagnosis Photodyn Ther

December 2023

Department of Dermatology, Daping Hospital, The Army Medical University, Chongqing, China. Electronic address:

Article Synopsis
  • * Four patients with confirmed M. marinum skin infections were treated; two with antibiotics alone and two with a combination of antibiotics and 5-aminolevulinic acid photodynamic therapy (ALA-PDT).
  • * All patients were successfully cured, with the combination therapy allowing for a shorter duration of antibiotic use and minimizing side effects.
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Article Synopsis
  • - A study discusses a rare case of a 71-year-old surfer who developed invasive endotracheal granulomatous disease due to a water-borne non-tuberculous mycobacterial pathogen, commonly known for causing skin infections.
  • - The patient was treated successfully with a 12-month regimen of azithromycin, ethambutol, and rifampicin, showing that endotracheal infections can be effectively managed.
  • - This case raises the question of whether such infections could also be contracted through inhaling contaminated water, as the patient had no prior skin or soft-tissue infections.
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Article Synopsis
  • The text discusses a case of a 27-year-old man who experienced cervical swelling and symptoms related to an infection after working on a cruise in the Douro river.
  • The infection was identified as rare and related to water activities, causing mainly skin and soft tissue problems, but in this case, it presented as cervical adenitis.
  • Diagnosis was confirmed through nucleic acid amplification tests, and treatment with rifampicin and clarithromycin led to an improvement in his symptoms and a reduction in swelling.
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: A Case-Based Narrative Review of Diagnosis and Management.

Microorganisms

July 2023

1st Division of Internal Medicine & Infectious Diseases Unit, University General Hospital of Ioannina, Faculty of Medicine, University of Ioannina, Str. Niarchou, 45500 Ioannina, Greece.

Article Synopsis
  • Skin and soft tissue infections from non-tuberculous mycobacteria are increasing in frequency, posing diagnostic challenges for healthcare providers.
  • A case study of a 66-year-old male showed painful nodules on his arm, worsened by anti-TNF-a treatment, and confirmed positive for mycobacteria after extensive testing.
  • The paper reviews the complexities of diagnosing and managing these infections, highlighting current trends in epidemiology, clinical characteristics, and treatment approaches.
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Article Synopsis
  • The text discusses a rare skin infection caused by an atypical bacterium primarily affecting workers in seafood processing and those handling fish, occurring after skin punctures.
  • It highlights a specific case of a female patient with chronic idiopathic myelofibrosis who developed a skin infection while being treated with the JAK inhibitor ruxolitinib, despite not having a known source of injury from fish.
  • The infection was diagnosed through histopathology and NGS sequencing, and the patient was successfully treated with antibiotics after 10 months, underscoring the importance of monitoring for infections as the use of JAK inhibitors increases.
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Induction of IL-32 in the immune response of keratinocytes to Mycobacterium marinum infection.

Exp Dermatol

September 2023

Shandong Provincial Hospital for Skin Diseases & Shandong Provincial Institute of Dermatology and Venereology, Shandong First Medical University & Shandong Academy of Medical Sciences, Jinan, China.

Article Synopsis
  • * Researchers conducted single-cell and bulk RNA sequencing on skin samples from patients with Mycobacterium marinum infection and found that certain genes, including IL-32, were significantly upregulated in infected keratinocytes.
  • * The study indicates that IL-32 may play a key role in how keratinocytes respond to M. marinum, suggesting potential new targets for treating chronic skin mycobacterial infections.
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Article Synopsis
  • - Mycobacterium marinum is a type of bacteria that causes skin and soft tissue infections, often linked to contact with contaminated water, especially in environments like fish tanks or pools.
  • - Infections typically develop about 21 days after exposure but can take up to 9 months for symptoms to appear; in this case, the patient had an erythematous plaque on his wrist for three months after exposure.
  • - The patient was successfully treated with a combination of oral ciprofloxacin and clarithromycin, leading to a positive outcome.
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Current treatment options for cutaneous infections.

Expert Opin Pharmacother

June 2023

Department of Clinical Microbiology, IIS-Fundación Jiménez Díaz, UAM, Madrid, Spain.

Article Synopsis
  • M. marinum is a nontuberculous mycobacterium that causes a skin condition known as fish tank granuloma, often linked to water exposure.
  • Treatment typically involves various antibiotics, depending on disease severity, with potential for new therapies like phage therapy and phototherapy being explored.
  • Medical treatment is preferred and usually effective, with surgical options available for small lesions when necessary.
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Comparative Evaluation of LAMP and Nested PCR for the Rapid Diagnosis of Infection.

Infect Drug Resist

March 2023

Department of Mycobacterium, Jiangsu Key Laboratory of Molecular Biology for Skin Diseases and STIS, Institute of Dermatology & Hospital of Skin Diseases, Chinese Academy of Medical Sciences & Peking Union Medical College, Nanjing, People's Republic of China.

Article Synopsis
  • The study aimed to evaluate rapid diagnostic methods (PCR, nested PCR, and LAMP) to improve the diagnosis of a specific skin infection, which typically takes weeks to culture.
  • It involved testing 6 strains and skin samples from infected patients to determine the effectiveness and sensitivity of LAMP and nested PCR compared to traditional PCR.
  • Findings showed that while nested PCR was the most sensitive, LAMP was easier and quicker to perform, making it a practical option for rapid diagnosis, especially in settings with limited resources.
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Combination treatment with antibiotics and photodynamic therapy in refractory mycobacterium marinum infection: A case report.

Photodiagnosis Photodyn Ther

June 2023

Shandong Provincial Hospital for Skin Diseases & Shandong Provincial Institute of Dermatology and Venereology, Shandong First Medical University & Shandong Academy of Medical Sciences, Jingshi Lu, Jinan, Shandong 27397, China.

Article Synopsis
  • Mycobacterium marinum is a bacterium that can lead to skin infections, which usually require long-term treatment with multiple drugs.
  • In some difficult cases, these treatments can cause issues like ineffectiveness, poor patient adherence, and sensitivity to the drugs.
  • A reported case demonstrated that using a combination of antibiotics and photodynamic therapy over two years successfully cured a challenging Mycobacterium marinum infection.
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Article Synopsis
  • Mycobacterium marinum is a rare skin pathogen that can cause chronic granulomas, with this study focusing on its dermoscopic features in patients.
  • A total of 27 patients were examined, revealing specific dermoscopic characteristics like yellowish-orange areas and various types of vascular structures.
  • The findings suggest that dermoscopy is a valuable, non-invasive tool for aiding in the diagnosis of M. marinum infections.
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