79 results match your criteria: "Muthayammal College of Arts & Science[Affiliation]"

The study synthesized Pluronic F-127 coated zinc oxide nanoparticles (PF-127ZnO NPs) using leaf extract and evaluated their antibacterial, antioxidant, and anticancer properties using various characterization methods such as UV-Vis, Fourier Transform Infra-Red, Photoluminescence spectroscopy, FESEM, EDAX, TEM, SAED, XRD, and DLS. The disc diffusion technique was used to evaluate the antibacterial properties of synthesized Pluronic F-127 coated zinc oxide nanoparticles against various pathogens and significant anticancer activity was noticed. The study examined the cytotoxicity of PF127ZnO nanoparticles to Hep3B cells .

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Zinc nanoparticles (ZnNPs) are a viable option in a number of disciplines, including cancer treatment, due to their special features. Among the several techniques for synthesizing ZnNP, biosynthesis with natural extracts is a highly effective and environmentally benign method, especially for uses in biomedicine. Using an aqueous extract of the marine red seaweed Jania rubens, we created a unique biosynthetic technique in this study to manufacture ZnNPs.

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Environmental pollution, being a major concern worldwide, needs a unique and ecofriendly solution. To answer this, researchers are aiming in utilizing plant extracts for the synthesis of nanoparticles. These NPs synthesized using plant extracts provide a potential, environmentally benign technique for biological and photocatalytic applications.

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Current research aims to screen the anticancer prospective of Leucas biflora phytocompounds against apoptotic regulator target protein essential for cancer progression. In gas chromatography-mass spectrometry analysis major phytocompounds such as tetracosahexaene, squalene, phytol, 22-stigmasten-3-one, stigmasterol, fluorene, and 1,4-dihydro were identified in ethanolic leaf extract of Leucas biflora. In vitro, the free radical scavenging potential of ethanolic leaf extract of Leucas biflora was examined through its DPPH and ABTS radical scavenging potential IC value 15.

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A simple sol-gel combustion process was employed for the creation of MFeO (M=Ni, Co) nanoparticles. The synthesized nanoparticles, acting as both photocatalysts and gas sensors, were analyzed using various analytical techniques. MFeO (M=Ni, Co) material improved the degradation of methylene blue (MB) under UV-light irradiation, serving as an enhanced electron transport medium.

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Article Synopsis
  • Supramolecular nanoparticles combining peptides and drugs, specifically pemetrexed gold nanoparticles (PEM-AuNPs), are being researched for their effectiveness in treating tumors, particularly in lung cancer.
  • The study utilized various analytical techniques to investigate PEM-AuNPs and found that they reduced cell viability in cancer cells (A549 and H1299) in a dose-dependent manner.
  • Biochemical staining techniques indicated that PEM-AuNPs induced apoptosis and generated reactive oxygen species, evidencing their enhanced anticancer properties.
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New cobalt(II), copper(II), and zinc(II) Schiff metal complexes were synthesized by the condensation reaction of 4-nitrobenzene-1,2-diamine with 3-4-(diethylamino)-2-hydroxybenzaldehyde. Fourier transform infrared, nuclear magnetic resonance, ultraviolet-visible, electron paramagnetic resonance, and high-resolution electrospray ionization mass spectrometry and powder X-ray diffraction were used to characterize the synthesized HL and its metal complexes. Conductance measurements, magnetic moment estimation, and metal estimation have all been determined and discussed.

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SrTiO/Ag nanocomposites were synthesized using a facile wet impregnation method, employing rigorous experimental techniques for comprehensive characterization. XRD, FTIR, UV, PL, FESEM, and HRTEM were meticulously utilized to elucidate their structural, functional, morphological, and optical properties. The electrochemical performance of the SrTiO/Ag nanocomposite was rigorously assessed, revealing an impressive specific capacitance of 850 F/g at a current density of 1 A.

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Impact of nanoparticles on human health and disease.

Nepal J Epidemiol

December 2023

Geriatrics and long term care department, Rumailah Hospital, Hamad Medical Corporation, Doha, Qatar.

Nanoparticles (NPs) are small particles with a surface area ranging from 1 to 100 nm in diameter that are rampantly used in different fields, e.g., medicine, engineering, and others.

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Globally, cancer is the leading cause of death and morbidity, and skin cancer is the most common cancer diagnosis. Skin problems can be treated with nanoparticles (NPs), particularly with zinc oxide (ZnO) NPs, which have antioxidant, antibacterial, anti-inflammatory, and anticancer properties. An antibacterial activity of zinc oxide nanoparticles prepared in the presence of 4-nitrobenzaldehyde (4NB) was also tested in the present study.

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The current investigation focuses on synthesizing copper oxide (CuO)-titanium oxide (TiO )-chitosan-farnesol nanocomposites with potential antibacterial, antifungal, and anticancer properties against Melanoma cells (melanoma cells [SK-MEL-3]). The nanocomposites were synthesized using the standard acetic acid method and subsequently characterized using an X-ray diffractometer, scanning electron microscope, transmission electron microscopy, and Fourier transform infrared spectroscopy. The results from the antibacterial tests against Streptococcus pneumoniae and Stapylococcus aureus demonstrated significant antibacterial efficacy.

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Introduction: Linalool is a monoterpene that occurs naturally in various aromatic plants and is identified in our previous study as a potential candidate for protection against high-fat diet (HFD)-induced metabolic dysfunction-associated steatotic liver disease (MASLD). However, little is known about its direct effects on hepatic lipid metabolism and oxidative stress. Therefore, this study aims to investigate the therapeutic effect of linalool against MASLD and the underlying mechanism.

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Recent efforts on the expansion of sustainable and commercial primal matters are essential to enhance the knowledge of their hazards and noxiousness to humans and their environments. For example, polysaccharide materials are widely utilized in food, wound dressing, tissue engineering, industry, targeted drug delivery, environmental, and bioremediation due to their attractive degradability, nontoxicity and biocompatibility. There are numerous easy, quick, and efficient ways to manufacture these materials that include cellulose, starch, chitosan, chitin, dextran, pectin, gums, and pullulan.

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Chitosan-encapsulated nickel oxide, tin dioxide, and farnesol nanoparticles: Antimicrobial and anticancer properties in breast cancer cells.

Int J Biol Macromol

September 2023

Muthayammal Centre for Advanced Research, Muthayammal College of Arts and Science, Rasipuram, Namakkal, Tamil Nadu 637408, India; Scigen Research and Innovation Pvt. Ltd., Periyar Technology Business Incubator, Thanjavur, Tamil Nadu, India.

Breast cancer is the most frequent cancer in women; however, it is curable in most cases (up to 80 %) when detected and treated at an early non-metastatic stage. Nanotechnology has led to the development of potential chemotherapeutic techniques, particularly for tumor treatment. Nanotechnology has therapeutic and pharmaceutical applications.

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beta-lactamases of Salmonella Sp. belongs to a group of enzymes produced by bacteria which break the beta-lactam ring to inactivate the beta-lactam antibiotic. Therefore, it is of interest to document the molecular docking analysis of beta-lactamase from Salmonella species with eicosane.

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In the present study, the green synthesis of silver nanoparticles (AgNPs) using ethanol extract of Cymodocea serrulata and biological activity were investigated by UV-visible spectrophotometer, Fourier-transform infrared spectroscopy (FTIR), x-ray powder diffraction (XRD), and scanning electron microscopy. The results show that nanoparticles synthesized were confirmed by color change from green to dark brown. The XRD analysis confirmed that the AgNPs were crystalline and found that their UV maximum specific absorbance was between 200 and 400 nm, and their field emission scanning electron microscopy size was between 60 and 69 nm.

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Purpose Of Review: This article provides the explanatory manuscript regarding the SARS-Corona virus 2. Sub-titled as the history of single-stranded RNA, internal characters of COVID-19, resource, the life cycle of COVID-19, reservoir of the disease, secondary infections of COVID-19 and nano herbal remedy.

Recent Findings: The skin is not the main target of the SARS-corona virus 2 infections but somehow directly or indirectly, it causes exacerbating eruptions on the skin.

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Article Synopsis
  • The aqueous extract of a specific plant acts as a precursor for quickly converting silver ions into silver nanoparticles (As-AgNPs), demonstrating significant antimicrobial activity against certain pathogens.
  • The study employed various analytical techniques, including UV-visible spectrophotometry and HR-TEM, confirming the presence and characteristics of As-AgNPs on fabrics, which showed effective inhibition against bacterial growth.
  • Green synthesis of silver nanoparticles offers a cost-effective, eco-friendly method for wound management, with no cytotoxic effects observed against L929 cell lines, suggesting potential for treating infectious ulcers.
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A green chemistry approach was employed to synthesize silica nanoparticles (SiNPs) using aqueous extract of Bryophyllum pinnatum leaf as capping agents. The novelty of this study was to produce silica nanoparticles using the biological method. An analysis of the physicochemical properties of formed nanoparticles was successfully completed through sophisticated characterization methods, such as UV-Visible absorbance spectroscopy, Fourier transform infra-red spectroscopy, X-ray diffraction, scanning electron microscope, energy dispersive X-ray, zeta potential analysis, and thermo-gravimetric analysis.

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The bioactives of Boswellia serrata have a role in ulcer healing therapies. Eleven bioactive compounds were obtained by GC-MS among which Cholan-24-oic acid, 3,12-bis (acetyl oxy) has a high molecular weight of 490.6719 with a retention time of 26.

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Nanomaterial is a rapidly growing area that is used to create a variety of new materials and nanotechnology applications from medical, pharmaceuticals, chemical, mechanical, electronics and several environmental industries including physical, chemical and biological nanoparticles are very important in our daily life. Nanoparticles with leaf extract from the healthy plant are important in the area of research using biosynthesis methods. Because of it's used as an environmentally ecofriendly, other than traditional physical and chemical strategies.

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Gastric cancer, invasive cancer of the gastrointestinal tract, found in developing countries. Chemotherapy to patients with advanced gastric cancer, exhibits greater drug resistance to standard chemotherapy drugs. Therefore, important to establish anti-cancer drugs that are successful for cancer therapy.

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Drug repurposing has been gaining increasing interest recently due to the reduction in development cost and reduced development timelines. Here, we report the antibacterial activity of the anticancer drug etoposide investigated in combination with the eggshell-derived hydroxyapatite (EHA). Hydroxyapatite (HA) is a well-known bioactive material with enhanced osteoconductivity and possesses superior drug delivery properties.

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Novel pure α-, β-, and mixed-phase α/β-BiO photocatalysts for enhanced organic dye degradation under both visible light and solar irradiation.

Environ Res

April 2022

Department of Environmental Energy Engineering, Kyonggi University, Republic of Korea; Faculty of Environmental and Food Engineering, Nguyen Tat Thanh University, 300A Nguyen Tat Thanh, District 4, Ho Chi Minh City, 700000, Vietnam. Electronic address:

Combining the pure α- and β-phases of bismuth oxide enhances its photocatalytic activity under both visible and solar irradiation. α-BiO, β-BiO and α/β-BiO were synthesized by a solvothermal calcination method. The structural, optical, and morphological properties of the as-synthesized catalysts were analyzed using XRD, UV-DRS, XPS, SEM, TEM, and PL.

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In this article, the supernatant of the soil-borne pathogen mn14 was used as the catalyst for the synthesis of AgNPs. The antibacterial and antifungal activity of Bs-AgNPs was evaluated, in which and showed susceptibility at 70 µL and 100 µL concentrations. Enzyme properties of the isolates, according to minimal inhibitory action and a growth-enhancing hormone-indole acetic acid (IAA) study of the isolates, were expressed in TLC as a purple color with an Rf value of 0.

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