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TNFα antagonization alters NOS2 dependent nasopharyngeal carcinoma tumor growth.
Cytokine
July 2015
Department of Biomedical Engineering, Boston University, Boston, MA, United States.
Tumor necrosis factor (TNFα) is a pro-inflammatory cytokine which mediates via nitric oxide (NO) several carcinogenic processes. Increasing evidences suggest that NO promotes inflammation induced growth of nasopharyngeal carcinoma (NPC). In patients, TNFα synthesis associates with poor survival.
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