5 results match your criteria: "Mustansiriyah University \ College of Medicine[Affiliation]"

Association of placental histopathological findings with COVID-19 and its predictive factors.

Rev Bras Ginecol Obstet

May 2024

Mustansiriyah University College of Medicine Department of Gynaecology and Obstetrics Baghdad Iraq Department of Gynaecology and Obstetrics, College of Medicine, Mustansiriyah University, Baghdad, Iraq.

Objective: The aims of the study are to describe the association of coronavirus disease (COVID-19) with the abnormal histopathological findings in human placenta and to highlight the potential predictors of these histopathological findings.

Methods: A retrospective cohort study, held in two obstetric units from January 2021- 2022, 34 patients who were confirmed cases of COVID- 19 were followed up till the time of delivery as their placenta were sent for histopathology. Patients diagnosed with other viral infections, chorioamnionitis, or were known case of as pre-term or term pre labour rupture of membrans (PROM) were excluded as well as pre exisiting diabetes mellitus or pre-eclampsia.

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Background: Physiologically, the spermatozoa are exposed to reactive oxygen species (ROS), and those ROS can strongly affect sperm's function through sperm capacitation. However, producing a high level of ROS reduces the sperm anti-oxidation system that may cause infertility, especially in cases with normal sperm count.

Purpose: To investigate the expression of the CYP24A1 gene in human spermatozoa and other oxidation-related biomarkers, including vitamin E, ROS, and catalase as added tools to predict male infertility.

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Background: COVID-19 infection has raised multiple concerns in pregnant mothers; many questioned the risk of vertical transmission and the implication on the feto-maternal outcome. Cardiotocogrm (CTG) is the principal method to observe intrapartum fetal well-being. This paper aims to verify intrapartum CTG changes seen in seropositive COVID-19 mothers versus healthy controls and looks into their relation to subsequent delivery mode and neonatal outcome.

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Article Synopsis
  • The study explores the roles of Neutrophil gelatinase-associated lipocalin (NGL) and Neutrophil/Lymphocyte (N/L) ratio in diagnosing and assessing the severity of preeclampsia (PE).
  • NGL levels were significantly higher in preeclampsia patients compared to healthy controls, demonstrating excellent sensitivity and specificity for diagnosing PE.
  • While the N/L ratio also differed between groups, it showed lower diagnostic performance compared to NGL, indicating that both factors are independently related to preeclampsia but serve different roles in diagnosis.
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Objectives: This study aims to evaluate the anti-arthritic effect of orally administered niclosamide (NCL) on collagen-induced arthritis (CIA) in rats.

Materials And Methods: The study included 35 Sprague Dawley rats (age range, 3 to 4 months; average weight, 100±10 g) of which seven were used as a negative control group (group A) whereas 28, in which arthritis was induced by injection of collagen type II emulsified by incomplete Freund's adjuvant and which were considered as CIA rats, were randomly divided equally into four groups and treated for 28 days with: normal saline (group B), low-dose NCL (group C), high-dose NCL (group D), and diclofenac sodium (group E). Body weight, arthritis index, ankle swelling, and footpad thickness were monitored before and after treatment in all groups.

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