Prioritised identification of structural classes of natural products from higher plants in the expedition of antimalarial drug discovery.

The emergence and spread of drug-recalcitrant Plasmodium falciparum parasites threaten to reverse the gains made in the fight against malaria. Urgent measures need to be taken to curb this impending challenge. The higher plant-derived sesquiterpene, quinoline alkaloids, and naphthoquinone natural product classes of compounds have previously served as phenomenal chemical scaffolds from which integral antimalarial drugs were developed.

Leveraging off higher plant phylogenetic insights for antiplasmodial drug discovery.

The antimalarial drug-resistance conundrum which threatens to reverse the great strides taken to curb the malaria scourge warrants an urgent need to find novel chemical scaffolds to serve as templates for the development of new antimalarial drugs. Plants represent a viable alternative source for the discovery of unique potential antiplasmodial chemical scaffolds. To expedite the discovery of new antiplasmodial compounds from plants, the aim of this study was to use phylogenetic analysis to identify higher plant orders and families that can be rationally prioritised for antimalarial drug discovery.

Impact assessment of increasing renewable energy penetration on voltage instability tendencies of power system buses using a QV-based index.

This paper presents a QV-based approach called Critical Voltage-Reactive Power Ratio (CVQR) index to assess the voltage instability tendencies of power system buses with increase in renewable energy (RE) penetration within the power system. The buses are thus ranked according to the order in which they are impacted by increase in renewable energy penetration. Simulations were performed using DIgSILENT PowerFactory and result analyses were done with MATLAB.

Techniques of power system static security assessment and improvement: A literature survey.

The secure operation of a power system depends on the available security evaluation tools and improvement techniques to tackle the disturbances or contingencies. The main objective of the survey presented in this paper is to provide a comprehensive review to the researchers, academicians, and utility engineers on the available techniques of static security assessment and improvement in modern power systems. Various performance indices are used to express the severity of limit violations from security margins typically in transmission line loading and buses voltage magnitude under a given disturbance or contingency.

Magnitude and determinants of food insecurity among pregnant women in Rwanda during the COVID-19 pandemic.

Globally, food insecurity is becoming a major public health concern, and has seriously been impacted by the COVID-19 pandemic. In the last decade, Rwanda has made significant improvement in terms of overall household food security. However, the magnitude of food insecurity among pregnant women is not well known.

Propagation path loss prediction modelling in enclosed environments for 5G networks: A review.

Millimeter wave path loss modeling is essential for reliable system design and accurate link budget calculations. The motivation for this research is that channel modeling in 5G millimeter wave propagation in an indoor environment is a current research topic in which capacity differences have been noticed as a result of different models being utilized. Existing models for future millimeter wave propagation must be tested and improved in order to aid link design.

Carotid intima media thickness (CIMT) in adults in the AWI-Gen Nairobi site study: Profiles and predictors.

Background: Carotid intima media thickness (CIMT) is used as a marker of subclinical and asymptomatic atherosclerotic vascular disease. Increased CIMT is associated with future cerebrovascular and cardiovascular events. There is limited data on the profile and correlates of CIMT in Africa.

Enhancing low voltage ride through capability of grid connected DFIG based WECS using WCA-PSO tuned STATCOM controller.

This paper investigates the utilization of a STATCOM to enhance the LVRT capability of a 9 MW DFIG based Wind Power Plant (WPP) during grid faults. The STATCOM under investigation is tuned using the Water Cycle Algorithm (WCA), Particle Swarm Optimization (PSO) and a hybrid algorithm of both WCA and PSO. Simulations are carried out in MATLAB programming software, using SimScape toolbox.

The global spread of misinformation on spiders.

In the internet era, the digital architecture that keeps us connected and informed may also amplify the spread of misinformation. This problem is gaining global attention, as evidence accumulates that misinformation may interfere with democratic processes and undermine collective responses to environmental and health crises. In an increasingly polluted information ecosystem, understanding the factors underlying the generation and spread of misinformation is becoming a pressing scientific and societal challenge.

An expert-curated global database of online newspaper articles on spiders and spider bites.

Mass media plays an important role in the construction and circulation of risk perception associated with animals. Widely feared groups such as spiders frequently end up in the spotlight of traditional and social media. We compiled an expert-curated global database on the online newspaper coverage of human-spider encounters over the past ten years (2010-2020).

Multiobjective optimal power flow for static voltage stability margin improvement.

Worldwide, utilities are aiming to increase the stability of modern power systems during system disturbances. Optimizing generation scheduling can improve system security in contingency and stressed conditions while lowering losses and generation costs. An efficient operating strategy for maintaining power system stability is proposed in this work.

Land use effects on termite assemblages in Kenya.

Termites perform key ecological functions and they also cause crop damage. Land use change resulting from agricultural intensification can result in changes in termite species diversity and abundance. Termite species occurring in natural vegetation, maize monocrop and maize-beans intercrop macrohabitats were investigated in Embu and Machakos Counties, Kenya.

Application of large-scale grid-connected solar photovoltaic system for voltage stability improvement of weak national grids.

This paper investigates the application of large-scale solar photovoltaic (SPV) system for voltage stability improvement of weak national grids. Large-scale SPV integration has been investigated on the Nigerian power system to enhance voltage stability and as a viable alternative to the aged shunt reactors currently being used in the Nigerian national grid to mitigate overvoltage issues in Northern Nigeria. Two scenarios of increasing SPV penetration level (PL) are investigated in this work, namely, centralized large-scale SPV at the critical bus and dispersed large-scale SPV across the weak buses.

Under voltage load shedding using hybrid ABC-PSO algorithm for voltage stability enhancement.

Voltage collapse tends to occur due to the voltage instability created during large faults. As a last resort, under-voltage load shedding (UVLS) is performed after all the available power operation and control mechanisms have been exhausted. Load shedding techniques have advanced from the conventional and adaptive methods that are less optimal compared to computational intelligence-based techniques.

Application and control of flexible alternating current transmission system devices for voltage stability enhancement of renewable-integrated power grid: A comprehensive review.

This paper presents a comprehensive review on the application and control of Flexible Alternating Current Transmission Systems (FACTS) devices in order to improve voltage stability of power grid with high share of renewable energy systems. The rise in the development of renewable energy technologies is driven by the attempts to mitigate the effects of global warming. In addition, global energy demand continues to rise as new electricity-driven systems such as electric vehicles are being developed and as remote locations are being connected to the grid.