1 results match your criteria: "Multiple Sclerosis and NeuroImmunology Imaging ProgramUniversity of Texas Southwestern Medical Center[Affiliation]"
Primary Progressive Multiple Sclerosis Evolving From Radiologically Isolated Syndrome.
Ann Neurol
February 2016
Department of Neurology & Neurotherapeutics, Clinical Center for Multiple Sclerosis, Multiple Sclerosis and NeuroImmunology Imaging ProgramUniversity of Texas Southwestern Medical Center, Dallas, TX.
Objective: The aim of this work was to evaluate the preprogressive phase in subjects with radiologically isolated syndrome (RIS) who evolve to primary progressive multiple sclerosis (PPMS).
Methods: A multicenter RIS cohort was previously established. Demographic, clinical, and radiological characteristics of subjects with RIS that evolved directly to PPMS were compared to those that developed a relapsing disease course from onset (clinically isolated syndrome [CIS] or relapsing-remitting MS) and were also compared to two other population- and clinic-based PPMS cohorts.