Two-stage surgical approach for type III odontoid fracture with C1-C2 fracture dislocation: a case report and management overview.

Introduction And Importance: Odontoid fractures of the second cervical vertebra (C2) are categorized into three types, with type III extending into the body of the axis. These fractures, often resulting from high-energy trauma, can cause significant instability and neurological issues. This case report discusses a 43-year-old male with a type III odontoid fracture and C1-C2 fracture dislocation, demonstrating the effectiveness of traditional neurosurgical techniques in managing such complex injuries.

An Act of Auto-Eroticism: Self-Urethral Insertion of Sewing Needle by an Old Man-A Case Report With Literature Review.

Self-insertion of foreign bodies into the urethra is uncommon and is often associated with complex psychological or behavioral factors. Many cases of foreign bodies in the urethra have been reported worldwide with variable complaints of penile pain, penile itching, dysuria, hematuria, and complete obstruction of urine. These foreign objects are managed to remove according to their size, complexity of shape, and location in the urethra.

Growth Differentiation Factor-15 versus Human Chorionic Gonadotropin in Pathophysiology of Nausea and Vomiting of Pregnancy.

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Identification of Novel Drug Molecules Against NS3-Like Helicase Enzyme of Alongshan Virus.

Alongshan virus (ALSV) is a novel tick-borne virus associated with human diseases. The ALSV is a segmented flavivirus from the family Flaviviridae. It is currently considered as tick-borne arbovirus.

Correlation Between Transient Elastography and Non-invasive Biomarker Scores for the Detection of Liver Fibrosis.

Background and aim The study aimed to address the need for reliable and non-invasive biomarkers (NIBM) for detecting fibrosis among patients with chronic liver disease (CLD). Material and methods This was a diagnostic validation study executed at the Department of Gastroenterology, Jinnah Hospital, Lahore. The study was carried out from July 2023 to June 2024, enrolling a total of 88 patients using non-probability consecutive sampling.

On the health effects of curcumin and its derivatives.

Turmeric () is an herbaceous plant that contains a phytochemical which is bright yellow and is known as curcumin. Turmeric, a member of Zingiberaceae family, has extensive application worldwide due to its beneficial medicinal attributes and is extensively used as a medicinal plant. Most people use turmeric as a spice, and it is a chief source of polyphenol curcumin.

A Comprehensive Case Report on Familial Multiple Lipomatosis.

Familial multiple lipomatosis (FML) is a rare autosomal dominant disorder characterized by the progressive development of encapsulated nodules predominantly on the trunk and extremities. Its genetic basis is linked to HMGA-2 gene over-expression. The condition is diagnosed via clinical history, ultrasound findings, and histological studies, and management mainly comprises surgical excision.

Periodontal and Caries Status in Relation to Oral Health Knowledge, Attitudes, and Behavior of Medical and Dental Students in Taxila, Pakistan.

Background The importance of oral health in general well-being is widely acknowledged. It is expected that students belonging to dental and medical fields maintain a strong awareness of oral health and participate in public oral health awareness and initiatives, particularly in low-income nations such as Pakistan. Objectives The objective of the study was to assess the relation of periodontal status and dental caries status of medical and dental students in Taxila, Pakistan, with their oral health knowledge, attitude, and behavior.

Baricitinib as monotherapy and with topical corticosteroids in moderate-to-severe atopic dermatitis: a systematic review and meta-analysis of dose-response.

Introduction: Atopic dermatitis (AD) is a chronic inflammatory skin disorder that affects millions worldwide, presenting challenges in managing symptoms and quality of life. Current treatments include topical corticosteroids (TCS), but novel approaches, such as Janus kinase (JAK) inhibitors, show promise. Baricitinib, a selective JAK1 and JAK2 inhibitor, targets cytokines involved in AD and offers potential benefits beyond traditional therapies.

Comparative Study of Inhaled Corticosteroids and Leukotriene Receptor Antagonists As Controller Options for Mildly to Moderately Persistent, Stable Asthma.

Introduction: Asthma is a chronic inflammatory disease of the airways characterized by bronchoconstriction, airway hyperresponsiveness, and variable airflow limitation. This results in symptoms such as wheezing, difficulty breathing, chest tightness, chest pain, and coughing.

Objectives: The primary objective of the study is to compare the efficacy of inhaled corticosteroids (ICS) versus leukotriene receptor antagonists (LTRA) in improving asthma control, lung function, and quality of life in patients with mild to moderate persistent asthma.

Exploring the genomic potential of Kytococcus schroeteri for antibacterial metabolites against multi-drug resistant Mycobacterium tuberculosis.

The versatile bacterium Kytococcus schroeteri is known for producing putative secondary metabolites. These include antimicrobials and other therapeutically significant compounds. The emergence of antibiotic-resistant pathogens has necessitated the exploration of possible sources for novel drug candidates.

Toxicity and Sublethal Effect of Chlorantraniliprole on Multiple Generations of L. (Diptera: Culicidae).

Due to the quick development of insecticide resistance, it is crucial to optimize management programs by understanding the sublethal effects of effective insecticides like chlorantraniliprole on L. populations. Using age-stage and two-sex life tables, we investigated the sublethal impacts of chlorantraniliprole on .

COMPARING STRESS LEVELS AMONG MEDICAL EMERGENCY UNIT WORKERS IN TEACHING HOSPITALS ACROSS LAHORE: A QUANTITATIVE ANALYSIS OF PRECISION.

Background: Stress is characterized as a condition of anxiety or tension spurred on by challenging circumstances. Stress is a normal human reaction that motivates us to deal with obstacles and dangers in our lives. The study aimed to investigate the levels of stress that employees in the medical emergency unit (MEU) industry face and any possible relationship between work satisfaction, and perceived stress.

PREVALENCE AND DETERMINANTS OF DEPRESSION AMONG AMPUTEES IN QUETTA REGION.

Background: Depression is increasingly diagnosed in the general population today. The loss of a limb through amputation, which can result in disfigurement, may also contribute to the development of depression despite pre-operative counselling. Understanding the factors associated with depression in individuals with limb amputation is important to effectively identify and manage this psychological condition.