4 results match your criteria: "Muhimbili University College Hospital[Affiliation]"

Antiphospholipid Antibodies and the Risk of Stroke in Urban and Rural Tanzania: A Community-Based Case-Control Study.

Stroke

October 2016

From the Department of Internal Medicine, Radboud University Medical Center, Nijmegen, The Netherlands (Q.d.M., A.J.v.d.V., P.G.d.G.); Department of Clinical Chemistry and Haematology, University Medical Center Utrecht, The Netherlands (J.E.M., P.G.d.G., R.T.U.); North Tyneside General Hospital, North Shields (W.K.G., R.W.W.); Kilimanjaro Christian Medical Centre, Moshi, Tanzania (A.J.); Muhimbili University College Hospital, Dar-es-Salaam, Tanzania (F.M.); and Institute of Health and Society, Newcastle University, Newcastle-upon-Tyne, United Kingdom (R.W.W.).

Background And Purpose: The burden of stroke is high in sub-Saharan Africa, and improved knowledge of risk factors is needed. Antiphospholipid antibodies are a common acquired stroke risk factor in young individuals. Antiphospholipid antibodies may be induced by infectious diseases.

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Objectives: The burden of stroke on healthcare services in sub-Saharan Africa (SSA) is increasing. However, long-term outcomes from stroke in SSA are not well described. We aimed to investigate case-fatality and health outcomes for stroke survivors at 7- to 10-year follow-up.

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Background: The burden of stroke on health systems in low-income and middle-income countries is increasing. However, high-quality data for modifiable stroke risk factors in sub-Saharan Africa are scarce, with no community based, case-control studies previously published. We aimed to identify risk factors for stroke in an incident population from rural and urban Tanzania.

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Background: Although the association between cerebrovascular and coronary artery disease (CAD) is well known in high-income countries, this association is not well documented in black Africans.

Aims: The aim of this study was to document electrocardiographic (ECG) evidence of CAD in stroke cases and controls and to identify other common ECG abnormalities related to known stroke risk factors in a community-based population of incident stroke cases in Tanzania, East Africa.

Methods: This was a case-control study.

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