2 results match your criteria: "Mugla Sitki Kocman University Training Research Hospital[Affiliation]"

Ribociclib, palbociclib and abemaciclib are currently approved CDK4/6 inhibitors along with aromatase inhibitors as the first-line standard-of-care for patients with hormone receptor-positive, HER2-negative metastatic breast cancer. The authors report retrospective real-life data for 600 patients with estrogen receptor- and/or progesterone receptor-positive and HER2-negative metastatic breast cancer who were treated with ribociclib and palbociclib in combination with letrozole. The results demonstrated that the combination of palbociclib or ribociclib with letrozole has similar progression-free survival and overall survival benefit in real life for the patient group with similar clinical features.

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Article Synopsis
  • Capnography measures carbon dioxide levels in breath, specifically focusing on the difference between pCO2 and ETCO2 during respiratory treatment.
  • This study evaluated whether ETCO2 could substitute for pCO2 in patients undergoing non-invasive mechanical ventilation (NIMV) due to respiratory issues like cardiogenic edema or COPD.
  • Findings showed significant differences between pCO2 and ETCO2 values in patients treated with NIMV, indicating that ETCO2 cannot replace pCO2 for monitoring these patients.
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