637 results match your criteria: "Mugla Sıtkı Kocman University Training and Research Hospital; Mugla-Turkey. bulent_ozlek@hotmail.com.[Affiliation]"

Effects of Intrauterine Isoproterenol Administration on Ovarian Follicular Development in Cows.

Vet Med Sci

January 2025

Department of Biochemistry, Faculty of Veterinary Medicine, Erzurum, Turkey.

Background: Isoproterenol (ISO) is a nonselective beta-adrenergic receptor agonist known for its vasodilatory effects. This experiment aims to investigate whether intrauterine ISO administration could alter vascular indices and follicular development in postpartum Holstein cows.

Objectives: The objectives are to evaluate the effects of intrauterine ISO administration on vascular changes and its impact on follicular development compared to placebo groups.

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The prognostic value of the neutrophil-lymphocyte ratio (NLR) in ischemic stroke remains debated due to cohort variability and treatment heterogeneity across studies. This study evaluates the relationship between admission NLR, stroke severity and 90-day outcomes in patients with anterior circulation large vessel occlusion (LVO) undergoing early, successful revascularization. A retrospective multicenter study was conducted with 1082 patients treated with mechanical thrombectomy for acute ischemic stroke.

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Childhood nutrition is critical for development however maternal feeding attitudes may influence feeding practices and subsequent outcomes. This study aimed to evaluate mothers' attitudes toward their children's feeding process and its relationship with characteristics and children's nutritional problems. One hundred thirty-five mother-child couples who attended the Social Pediatrics Outpatient Clinic of a hospital participated in the study.

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Purpose: To evaluate the role of Streptococcus pneumoniae, Staphylococcus aureus, Haemophilus influenzae, Serratia marcescens, and Moraxella catarrhalis in the nasal and ocular surface flora, along with their metabolic activities in children with unilateral congenital nasolacrimal duct obstruction (CNLDO).

Methods: Swabs were taken from the bilateral inferior meatus and ocular surface of 26 children with unilateral CNLDO before probing. Nasal and ocular surface swabs from non-operated eyes of children who underwent unilateral blepharoptosis or strabismus surgery formed the control group.

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Introduction: Gestational diabetes mellitus (GDM) is defined as glucose intolerance during pregnancy. We aimed to investigate the potential effects of betatrophin and ApoC2 in GDM, focusing on their roles in LPL (lipoprotein lipase) regulation and their relationship with hPL to elucidate the possible impact of hPL on lipid metabolism and its potential contribution to the development of GDM.

Methods: Thirty pregnant women with normal glucose tolerance and 29 with gestational diabetes mellitus (diagnosed by 75g OGTT between 24 and 28 weeks) were included in the study.

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Article Synopsis
  • Lung cancer is a significant issue for patients with Idiopathic Pulmonary Fibrosis (IPF), but there is limited research on those with non-IPF Pulmonary Fibrosis (PF); this study compares the two groups in terms of characteristics and survival.
  • The study analyzed data from 251 patients diagnosed with lung cancer between 2010 and 2022, finding that most were elderly men with a high smoking rate, and differing patterns of lung imaging between the two groups.
  • Both IPF-LC and non-IPF PF-LC patients had high 5-year mortality rates around 64%, with the shortest survival noted in non-IPF PF patients with unclassified PF.
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The Effect of Music on Preoperative Fear and Anxiety in Patients Undergoing Thyroid Surgery: A Randomized Controlled Trial.

J Perianesth Nurs

December 2024

Department of Nursing, Faculty of Health Sciences, Mugla Sıtkı Kocman University, Mugla, Turkey. Electronic address:

Purpose: This study aimed to investigate the impact of music on preoperative fear and anxiety in patients undergoing thyroid surgery.

Design: This was a randomized controlled prospective study.

Methods: This study was conducted at the general surgery clinic of a training and research hospital from April 10, 2021 to April 1, 2022.

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Article Synopsis
  • The study compared the effectiveness and safety of FOLFIRI combined with bevacizumab versus FOLFIRI combined with aflibercept in patients with RAS-mutant metastatic colon cancer who had previously received treatment.
  • Results showed that patients receiving FOLFIRI with bevacizumab had a median overall survival (OS) of 14.1 months and progression-free survival (PFS) of 7.7 months, which were significantly better than those treated with aflibercept (OS: 11.2 months, PFS: 5.7 months).
  • Additionally, the bevacizumab group experienced fewer severe side effects (50.9% in aflibercept group vs 25.
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Objectives: Adolescence is defined as the transition period from childhood to adulthood. The present study aimed to examine the relationship between health promotion behavior and game addiction in a sample of Turkish adolescents.

Methods: The sample consisted of 340 adolescents aged 10-14 years (50.

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Acute pancreatitis (AP) is a clinical condition that arises acutely in the pancreas through various inflammatory pathways due to multiple causes. Turkish Society of Gastroenterology Pancreas Working Group developed comprehensive guidance statements regarding the management of AP that include its epidemiology, etiology, clinical presentation, diagnostic criteria, disease severity, treatment, prognosis, local and systemic complications. The statements were developed through literature review, deliberation, and consensus opinion.

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Outbreaks of mushroom poisoning associated with acute kidney injury.

Hum Exp Toxicol

November 2024

Department of Internal Medicine, Division of Endocrinology, Faculty of Medicine, Usak University, Usak, Turkey.

Introduction: The outbreak of acute kidney injury (AKI) due to mushroom poisoning is not a frequently encountered medical challenge. Herein, we present 13 mushroom poisoning cases associated with AKI related to causing poisoning reported in a short time period in Turkey.

Methods: A total of 13 patients with AKI due to mushroom poisoning admitted to Usak Research and Training Hospital between November and December 2020 were included.

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Analysis of Cesarean Section Ratios by Robson Classification.

J Obstet Gynaecol India

October 2024

İzmir Ekonomi University, Medical Point Hospital, Obstetrics and Gynecology Department, İzmir, Turkey.

Background And Aim: Cesarean section (CS) is a delivery method, which is used to avoid the complications of vaginal delivery, maternal and neonatal morbidity, and mortality. It has become the most applied surgical procedure both in Türkiye, and globally. In 2013, Robson et al.

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Factors affecting the use of salbutamol before hospital admission in children with asthma exacerbation.

Allergol Immunopathol (Madr)

November 2024

Division of Pediatric Allergy and Immunology, University of Health Sciences, Ankara City Hospital, Ankara, Turkey.

Background: Early home intervention for asthma exacerbation (AE) in children is associated with more favorable outcomes. Inhaled short-acting beta agonists (SABA) are the cornerstones of AE treatment.

Objectives: We aimed to determine what proportion of parents administered salbutamol to their children to treat asthma exacerbation at home, and the factors affecting the decision to administer the medication.

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Cardiomyopathy, which is shortly defined as a disease of the myocardium, has a broad definition that includes many different diagnoses. Recent advances in cardiac imaging techniques, including basic and advanced echocardiography, computed tomography, nuclear medicine, and cardiac magnetic resonance, allow for a more accurate evaluation of volumes and thickness of cardiac chambers, systolic and diastolic function of the ventricules, and tissue structure. Multimodality imaging often provides the first clinical suspicion for specific etiologies, especially when the medical and family history is unclear, by identification of red flags of underlying systemic diseases.

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Purpose: The study aimed to investigate the association between urinary incontinence (UI) severity, pelvic pain, and sensory-motor function in older women with stroke.

Methods: A cross-sectional prospective study was carried out with 102 older women individuals with stroke. Barthel Index (BI), Incontinence Impact Questionnaire Short Form (IIQ-7), Urogenital Distress Inventory (UDI-6), Pelvic Pain Impact Questionnaire (PPIQ), Somatosensory Amplification Scale (SASS), and Somatic Sensitivity Scale (SeSS) were used for clinical measurements.

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Background: This study aims to examine leptin and ghrelin gene polymorphisms and serum levels in children with autism spectrum disorder (ASD).

Methods: The study comprised a case group of 40 children aged 2-7 diagnosed with ASD and a control group of 40 healthy children. The severity of ASD symptoms was assessed using the Childhood Autism Rating Scale and the Autism Behavior Checklist.

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Objective: To evaluate the etiology-specific diagnosis of early-onset developmental epileptic encephalopathies (EO-DEEs) in a nationwide Turkish cohort to determine the implications for therapeutic management.

Methods: The cohort comprised 1450 patients who underwent EO-DEE. The utility of genetic testing was assessed with respect to the initial phases of next generation sequencing (NGS) (2005-2013) and the current NGS era (2014-2022).

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Following the results of the phase 3 KEYNOTE-522 trial, the U.S. Food and Drug Administration approved pembrolizumab, a humanized IgG4 kappa monoclonal antibody, in combination with neoadjuvant chemotherapy as a new standard of care for high-risk early-stage triple-negative breast cancer (TNBC).

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Article Synopsis
  • The study examines the role of Her2 status in early stage triple negative breast cancer (TNBC) patients undergoing neoadjuvant chemotherapy, revealing conflicting results regarding its prognostic impact.
  • A total of 620 female TNBC patients were analyzed, with 68.9% having Her2-0 and 31.1% having Her2-low status; the rates of pathological complete response (pCR) were similar between these groups.
  • While the Her2-0 group showed better disease-free survival (DFS), the overall survival (OS) rates were similar between the two groups, indicating the need for further research into the implications of Her2 status in this treatment context.
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Background: Foot care self-management is underutilized in older adults and diabetic foot ulcers are more common in older adults. It is important to identify predictors of foot care self-management in older adults with diabetes in order to identify and support vulnerable groups. This study aimed to identify predictors of foot care self-management in older adults with diabetes using a machine learning approach.

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Article Synopsis
  • The study explores how different sexual positions impact ejaculation duration and the overall control of ejaculation, which is important for sexual pleasure.
  • Conducted through an online survey with 1904 heterosexual men aged 18-65, it looked at factors related to premature ejaculation (PE) and how these men engage in various sexual positions.
  • Results indicated a significant preference for doggy style across all groups, with non-PE participants more likely to change positions when close to ejaculation compared to PE participants, suggesting that adjusting sexual positions may help manage PE.
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Evaluation of contraception methods in chronic myeloid leukemia patients: A Turkish multicenter study.

J Oncol Pharm Pract

September 2024

Division of Haematology, Department of Internal Medicine, Cerrahpaşa Faculty of Medicine, İstanbul University-Cerrahpaşa, Istanbul, Turkey.

Background And Aim: Chronic myeloid leukemia (CML) incidence has recently increased in younger individuals. With time, given the nature of the disease and available therapies, as well as the existing paucity and inconsistency of advice, worries about fertility have surfaced. With all these clear unknowns, we designed this study to raise awareness among both physicians and CML patients about whether male and female patients of childbearing age were using contraception at the time of diagnosis, and if so, which methods they were using.

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Purpose: Obstructive Sleep Apnea (OSA) is the most common sleep-related disorder. Interoception is the collection of sensory and cognitive processes that involve receiving and interpreting physiological signals from internal body structures and conveying the perception of inner sensations. In this study, it was hypothesized that the impairment in cognitive functions associated with chronic hypoxemia and the insular effects due to OSA would negatively affect interoceptive functions.

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Purpose: In advanced breast cancer, endocrine therapy is preferred in the absence of visceral crisis. Cyclin-dependent kinase inhibitors (CDKi) are the gold standards. The selection of subsequent treatments after CDKi treatment is still controversial, and the efficacy of everolimus (EVE) combinations is unknown.

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