Validation of the ONKOTEV Risk Prediction Model for Venous Thromboembolism in Outpatients With Cancer.

Importance: The assessment of the risk of venous thromboembolism (VTE) among outpatients with cancer represents an unsolved topic. Current international guidelines recommend primary prophylaxis for patients at intermediate to high risk of VTE, indicated by a Khorana score of 2 or more. A previous prospective study developed the ONKOTEV score, a 4-variable risk assessment model (RAM) consisting of a Khorana score of more than 2, metastatic disease, vascular or lymphatic compression, and previous VTE event.

Prognostic factors for recurrence and survival in anal cancer: generating hypotheses from the mature outcomes of the first United Kingdom Coordinating Committee on Cancer Research Anal Cancer Trial (ACT I).

Background: Only 2 prospective studies have previously reported prognostic factors for anal cancer, European Organization for Research and Treatment of Cancer trial 22861 (EORTC 22861) and Radiation Therapy Oncology Group trial 98-11 (RTOG 98-11). Both of those trials reported that clinically positive lymph nodes and male sex predicted poorer overall survival (OS). The EORTC 22861 trial indicated that the same factors were prognostic for locoregional control.

Supercooling points of Lysiphlebus testaceipes and its host Schizaphis graminum.

Supercooling points (SCPs) were measured for various life stages of male and female Lysiphlebus testaceipes (Cresson) parasitoids, along with mummies and its aphid host, Schizaphis graminum (Rondani). Some parasitoids were acclimated (4 h at 10 degrees C before cooling down to the SCP) to determine whether this could significantly lower the SCP. Acclimation did not improve SCPs for L.

Integrating case management and psychiatric hospitalization.

Although case management programs attempt to reduce the use of psychiatric hospitalization for clients with long-term mental illness, inpatient treatment still is required for many individuals in even the best community support systems. Even when formal mechanisms for hospital-community liaison exist, there often is little effective collaboration between hospital and community treatment staffs. Depleted from struggling with relapsing patients, case managers often discontinue their efforts during hospitalization.

Clinical case management: definition, principles, components.

The burgeoning field of case management for long-term psychiatric patients has been handicapped by a lack of conceptual models that delineate the diverse activities of case managers. Based on the actual practice of case management, the author outlines a model of clinical case management that moves beyond the view of the case manager as a systems coordinator, service broker, or supportive companion. Using a contemporary biopsychosocial model of mental illness, the clinical case management model integrates the clinical acumen, personal involvement, and environmental interventions needed to address the overall maintenance of the patient's physical and social environment.