2 results match your criteria: "Mount Sinai Medical Center and Florida International University[Affiliation]"

Lack of patient diversity in clinical trial enrollment remains an obstacle to achieving equitable healthcare outcomes. Under-representation has resulted in non-generalizable clinical knowledge, inequitable access to treatment, and health disparities among minority and disadvantaged groups. A multidisciplinary panel was convened to consider the challenges of diverse patient accrual and provide actionable solutions to improve representation in clinical trials.

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Article Synopsis
  • Giant cell arteritis (GCA) is the most common type of systemic vasculitis in older adults, diagnosed through temporal artery biopsy, which often yields negative results despite the condition's progression in some patients.
  • A study analyzed varicella-zoster virus (VZV) infection in temporal arteries (TAs) from patients suspected of having GCA but with negative biopsy results, as well as normal TAs from age-matched individuals.
  • The findings showed a significantly higher presence of VZV antigen in GCA-negative (64%) and GCA-positive (73%) TAs compared to normal TAs (22%), suggesting a potential link between VZV infection and GCA pathology.
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