In silico network pharmacology analysis and molecular docking validation of Swasa Kudori tablet for screening druggable phytoconstituents of asthma.

Traditional medicines are impactful in treating a cluster of respiratory-related illnesses. This paper demonstrates screening active, druggable phytoconstituents from a classical Siddha-based poly-herbal formulation called Swasa Kudori Tablet to treat asthma. The phytoconstituents of Swasa Kudori are identified as Calotropis gigantea, Piper nigrum, and (Co-drug) Abies webbiana.

In silico network pharmacology study on Glycyrrhiza glabra: Analyzing the immune-boosting phytochemical properties of Siddha medicinal plant against COVID-19.

Immunosenescence is a pertinent factor in the mortality rate caused by Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2). The changes in the immune system are strongly associated with age and provoke the deterioration of the individual's health. Traditional medical practices in ancient India effectively deal with COVID-19 by boosting natural immunity through medicinal plants.

Current trends in bioremediation and bio-integrated treatment of petroleum hydrocarbons.

Petroleum hydrocarbons and their derivatives constitute the leading group of environmental pollutants worldwide. In the present global scenario, petroleum and natural gas production, exploration, petroleum refining, and other anthropogenic activities produce huge amounts of hazardous petroleum wastes that accumulate in the terrestrial and marine environment. Due to their carcinogenic, neurotoxic, and mutagenic characteristics, petroleum pollutants pose severe risks to human health and exert ecotoxicological effects on the ecosystems.

Mycobacterium tuberculosis and its clever approaches to escape the deadly macrophage.

Mycobacterium tuberculosis (Mt.b), a deadly disease causer, is a facultative parasite. This microorganism has developed several methods to defend itself, once internalized within specialised vacuoles in the macrophages.

Physical Activity Levels, Motivators and Barriers to Exercise among Men and Women Aged 30 to 50 Years in Rourkela, India.

Background: Literature suggests that middle age is a period with increasing sedentary behavior and health risks.

Objective: We conducted the present study to assess physical activity levels of the adults aged 30-50 years and understand the motivators and barriers to regular physical activity.

Materials And Methods: A cross-sectional study was conducted among 100 adults aged 30-50 years residing in Rourkela, Odisha.

FOXO1: a pivotal pioneer factor in oral squamous cell carcinoma.

The transcription factor FOXO1 regulates cell cycle progression, apoptosis and oxidative stress. Interestingly, numerous studies have implicated their positive role in tumor suppression, angiogenesis and metastasis in oral squamous cell carcinoma (OSCC). Distinct post-transcriptional and post-translational modifications actuate the physiological role of FOXO1 in OSCC.

Diet diversity of urban households in India during the COVID-19 lockdown.

The nature of the COVID-19 pandemic forced several nations to impose country-wide lockdowns. The lockdown impacted several aspects of life including the economy. Food security became a growing concern for many households.