27 results match your criteria: "Moulana College of Pharmacy[Affiliation]"
Comparative Expression Profiling and Sequence Characterization of ATP1A1 Gene Associated with Heat Tolerance in Tropically Adapted Cattle.
Animals (Basel)
August 2021
School of Sustainable Food and Farming, Harper Adams University, Edgmond, Newport TF10 8NB, UK.
Climate change is an imminent threat to livestock production. One adaptation strategy is selection for heat tolerance. While it is established that the gene and its product play an important role in the response to many stressors, there has been no attempt to characterize the sequence or to perform expression profiling of the gene in production animals.
View Article and Find Full Text PDFDevelopment of 2D, 3D-QSAR and Pharmacophore Modeling of Chalcones for the Inhibition of Monoamine Oxidase B.
Comb Chem High Throughput Screen
September 2022
Postgraduate Program in Natural and Synthetic Bioactive Products, Federal University of Paraíba, 58051-900, João Pessoa, Brazil.
Background: Selective and reversible types of MAO-B inhibitors have emerged as promising candidates for the management of neurodegenerative diseases. Several functionalized chalcone derivatives were shown to have potential reversible MAO-B inhibitory activity, which have recently been reported from our laboratory.
Methods: With the experimental results of about 70 chalcone derivatives, we further developed a pharmacophore modelling, and 2D and 3D- QSAR analyses of these reported chalcones for MAOB inhibition.