Tolerability and outcome of palliative treatment for metastatic pulmonary carcinoma in cats.

Objectives: Pulmonary carcinoma is uncommon in cats and reporting of outcomes following medical treatment is limited, especially in presence of metastases. The aim of this study was to describe the outcome of cats affected by metastatic primary pulmonary carcinoma and to evaluate the tolerability of palliative treatment in this patient population.

Materials And Methods: Medical records were searched for cats with a cytological or histopathological diagnosis of primary pulmonary carcinoma and evidence of metastatic disease.

The traditional and modifiable risk factors of coronary artery disease - a community-based cross-sectional study among 2 populations.

A community-based cross-sectional study was undertaken by the Cardiology Society of India (Kerala Chapter) to determine the prevalence of coronary artery disease (CAD) and its risk factors. The periodontal health status of the rural and urban participants in the Thiruvananthapuram district of Kerala was evaluated to document any association between periodontal disease (PD) and CAD and to describe any shared risk factors.The participants were selected using a multistage cluster random sampling method.

Ventral acetabular augmentation for management of caudoventral luxation following total hip replacement in dogs.

Objective: To report ventral acetabular augmentation with an internal fixator for management of caudoventral luxation following total hip replacement in dogs and to report clinical outcomes.

Materials And Methods: Clinical records from three UK-based referral hospitals were reviewed retrospectively between 2010 and 2020 to identify dogs with caudoventral hip luxation managed by ventral acetabular augmentation. Hip prosthesis component orientation was radiographically assessed to identify potential risk factors associated with the luxation.

Postoperative bleeding in essential thrombocytosis patients with colorectal cancer: Case report and literature review.

Introduction And Importance: Essential thrombocythemia (ET) is a myeloproliferative disorder characterized by increased platelet count and a high risk of bleeding or thrombotic events due to platelet dysfunction. Patients with ET are treated according to their risk of complications with cytoreductive or anti-aggregant treatment. Neither guidelines for oncologic patients nor perioperative management of patients with ET have been determined.

Successful management of aspiration pneumopathy without antimicrobial agents: 14 dogs (2014-2021).

Objectives: To describe clinical cases of aspiration pneumonitis and pneumonia in dogs, which were successfully managed without antimicrobials.

Materials And Methods: Retrospective case review of dogs presenting to a referral teaching hospital between February 2014 and February 2021. Cases were included when a clinical diagnosis of aspiration pneumopathy was made (requiring one or more of the following: radiographic evidence of an aspiration pneumopathy, endotracheal airway sampling consistent with aspiration and/or a positive endotracheal airway sample culture) which was not treated with antimicrobial therapy.

Musculoskeletal magnetic resonance imaging in the DE50-MD dog model of Duchenne muscular dystrophy.

The DE50-MD canine model of Duchenne muscular dystrophy (DMD) has a dystrophin gene splice site mutation causing deletion of exon 50, an out-of-frame transcript and absence of dystrophin expression in striated muscles. We hypothesized that the musculoskeletal phenotype of DE50-MD dogs could be detected using Magnetic Resonance Imaging (MRI), that it would progress with age and that it would reflect those in other canine models and DMD patients. 15 DE50-MD and 10 age-matched littermate wild type (WT) male dogs underwent MRI every 3 months from 3 to 18 months of age.

Traumatic stifle injury in 72 cats: a multicentre retrospective study.

Objectives: The aim of the study was to describe traumatic stifle injury in cats and report complications and long-term outcome.

Methods: The medical records from seven veterinary hospitals of cats treated for traumatic stifle injury were reviewed. Long-term follow-up data were collected from referring veterinarians and using the Feline Musculoskeletal Pain Index, collected from owners.

CT findings, management and short-term outcome of dogs with pyothorax: 101 cases (2010 - 2019).

Objectives: To describe diagnosis, CT findings, management and short-term outcome of a large population of canine pyothorax cases.

Methods: Retrospective analysis of 101 canine pyothorax cases at two UK referral centres. Medical records and CT images were reviewed.

Revisiting the original Akin technique: A comparative analysis of radiographic outcome.

Background: The Akin osteotomy is widely used to correct the hallux valgus and different fixation techniques have been proposed. Currently most of these procedures coexist, with disagreement on which offers the best results. The aim of this study is to compare the radiological outcome of the original Akin's technique with one in which a staple was used to stabilize the osteotomy.

Growth Patterns of Indonesian Infants with Cow's Milk Allergy and Fed with Soy-Based Infant Formula.

Purpose: The use of soy-based infant formula has increased widely in infants with cow's milk allergy (CMA). This study aimed to provide evidence on the growth pattern of CMA infants fed with soy-based infant formula in an Indonesian setting.

Methods: A multi-site, intervention study was conducted among full-term and normal birth weight CMA infants.

A multicenter retrospective study into endogenous causes of uveitis in cats in the United Kingdom: Ninety two cases.

Purpose: The purpose of this study was to investigate the most common causes of endogenous feline uveitis in a UK referral population and to investigate associations based on signalment.

Methods: Retrospective multicenter cross-sectional study from 2010 to 2019 including cats presented to the Animal Health Trust and the Royal Veterinary College with clinical signs consistent with uveitis. Cats were included in analyzes if they had a full physical examination including an ophthalmic examination, complete blood count, serum biochemistry, and infectious disease testing for at least two diseases unless the diagnosis was found on clinical examination (eg, neoplasia).

An unusual case of neutrocytic, culture-negative meningitis in an immunocompetent adult.

Patient presenting with fever, acute onset seizure and neck stiffness on examination; deteriorating despite initiation of early treatment for meningitis.

An international genome-wide meta-analysis of primary biliary cholangitis: Novel risk loci and candidate drugs.

Backgrounds & Aims: Primary biliary cholangitis (PBC) is a chronic liver disease in which autoimmune destruction of the small intrahepatic bile ducts eventually leads to cirrhosis. Many patients have inadequate response to licensed medications, motivating the search for novel therapies. Previous genome-wide association studies (GWAS) and meta-analyses (GWMA) of PBC have identified numerous risk loci for this condition, providing insight into its aetiology.

Sustainable veterinary anaesthesia: single centre audit of oxygen and inhaled anaesthetic consumption and comparisons to a hypothetical model.

Objectives: Single centre carbon footprint audit of oxygen and inhaled anaesthetic agent consumption.

Study Design: Retrospective audit with hypothetical intervention.

Materials And Methods: Records of 100 consecutive anaesthetics were examined.

The Value of Companion Dogs as a Source of Social Support for Their Owners: Findings From a Pre-pandemic Representative Sample and a Convenience Sample Obtained During the COVID-19 Lockdown in Spain.

Dogs are a source of companionship and comfort for their owners, but the degree to which this might translate into real emotional and social support has not been quantified. Emotional and social support are essential to help people to get through personal crises such as bereavement. In this study we characterize the social support owners obtain from their dogs, provide evidence of how widespread this social support is amongst dog-owners, and show how social support from dogs can increase during a crisis (using the COVID-19 pandemic as an example).

Cerebellar developmental venous anomaly with associated cavernoma causing a hemorrhage - a rare occurrence.

Developmental venous anomalies (DVAs) are variations in the transmedullary veins required for drainage of the brain. Normally, when occurring in isolation, DVAs are not clinically significant and are therefore usually a benign diagnosis. Thus, they are most often an incidental finding unless associated with an adjacent pathology.

Medium Term Radiographic and Clinical Outcomes Using a Modular Tapered Hip Revision Implant.

Background: The rate of revision hip arthroplasty surgery is rising. Surgeons must use implants with proven outcomes to help overcome the technical challenges faced during revision surgery. However, outcome studies using these implants are limited.

Description of different ultrasound guided transversus abdominis plane block in pig cadavers - A pilot study.

Objective: To develop an ultrasound (US)-guided transversus abdominis plane (TAP) block in pigs.

Study Design: Prospective, descriptive, experimental study.

Animals: A total of 26 hemi-abdomens belonging to 13 Seghers Hybrid cadavers.

Traumatic physeal fractures in cats: a review of 36 cases (2010-2020).

Objectives: The aim of this study was to describe the demography, aetiology, location and classification of physeal fractures in cats, and to describe their management and outcomes.

Methods: Clinical records and radiographs of cats referred for management of physeal fractures were retrospectively reviewed. Fractures of the proximal femoral physis were excluded.

Comparing the behaviour of dogs before and after enucleation due to glaucoma.

Purpose: There is limited literature on owner's attitudes towards enucleation and behavioural changes after enucleation in dogs. The aim of this study is to investigate the owner's perception of canine enucleation as well as gain insight into the behavioural changes of dogs before and after enucleation due to glaucoma.

Methods: This retrospective study involved a questionnaire sent to the owners whose dogs were diagnosed with glaucoma and underwent enucleation at the Queen Mother Hospital for Animals between June 2015 and January 2018.

Proposing the VetCompass clinical grading tool for heat-related illness in dogs.

Heat-related illness is a potentially fatal condition in dogs. Rapid and accurate recognition of the severity can improve clinical management in affected dogs and lead to better outcomes. This study explored retrospective VetCompass veterinary clinical records to investigate the clinical signs recorded for dogs presenting with heat-related illness to primary-care veterinary practice from 2016 to 2018.

Changes in retinal vascular diameters in senior and geriatric cats in association with variation in systemic blood pressure.

Objectives: Early diagnosis of arterial hypertension is essential to prevent target organ damage. In humans, retinal arteriolar narrowing predicts hypertension. This blinded prospective observational study investigated the retinal vessel diameters in senior and geriatric cats of varying systolic blood pressure (SBP) status and evaluated retinal vascular changes in hypertensive cats after treatment.

One-year clinical outcome of patients with nonvalvular atrial fibrillation: Insights from KERALA-AF registry.

Background: We report patient characteristics, treatment pattern and one-year clinical outcome of nonvalvular atrial fibrillation (NVAF) from Kerala, India. This cohort forms part of Kerala Atrial Fibrillation (KERALA-AF) registry which is an ongoing large prospective study.

Methods: KERALA-AF registry collected data of adults with previously or newly diagnosed atrial fibrillation (AF) during April 2016 to April 2017.