[Laparoscopic retropubic adenomectomy in patients with giant prostate adenoma].

A clinical case of operative treatment of a 71-year-old patient with diagnosis "Prostate hyperplasia. Cystoma from 26.06.

A Systematic Review and Case Illustrations of Misdiagnosing Intracranial Aneurysms.

Modern neuroimaging methods do not completely rule out false diagnoses of intracranial aneurysms which can lead to an unwarranted operation associated with risks of complications. However, surgical interventions for falsely diagnosed aneurysms are quite rare. The purpose of this study is to demonstrate two clinical cases of false-positive aneurysms and a systematic review of the literature dedicated to the incidence and etiology of false-positive aneurysms, identifying risk factors associated with false-positive aneurysms.

Microsurgical Clip Reconstruction of a True Posterior Communicating Artery Aneurysm.

Approximately 25% of intracranial aneurysms originate at the internal carotid artery and posterior communicating artery (PCoA) junction. In contrast to typical PCoA aneurysms, which are usually saccular, a subset known as true PCoA aneurysms arise directly from the PCoA. These represent about 1.

Randomized multicenter noninferiority phase III clinical trial of the first biosimilar of eculizumab.

Currently, eculizumab is the main effective treatment for paroxysmal nocturnal hemoglobinuria (PNH). The aim of this randomized multicenter noninferiority study was to evaluate the efficacy and safety of the Biosimilar (Elizaria) in comparison with the Originator (Soliris) in patients with PNH. Biosimilar and Originator were administered at a dose of 600 mg weekly for 4 weeks at the initial stage in naive patients, as well as for maintenance therapy at a dose of 900 mg every 2 weeks in all patients.

[Method of endonasal endoscopic dacryocystorhinostomy with plastic stoma formation].

The article presents modern methods of surgical treatment of chronic dacryocystitis, a brief historical review of various options for endonasal endoscopic dacryocystorhinostomy is carried out. The method of plastic seamless formation of dacryocystostomy, which does not require intubation of the lacrimal passages and/or using of silicone stoma dilators, is described. Between 2010 and 2019 at The State Budgetary Healthcare Institution of Moscow Area Moscow regional research clinical institute .

[Epidemiology and diagnosis of mutations in the ALK gene in patients with non-small cell lung cancer in the Moscow region].

Aim Of Study: To determine a diagnostic algorithm for detecting translocation of the gene and its frequency in the Moscow region.

Materials And Methods: During the priod between 2014 and 2018 (inclusive), 488 patients without activating mutations in the gene in the Moscow region were tested. To detect translocation of the ALK gene, fluorescence hybridization (FISH) methods, an immunohistochemical method, and, in some cases, a polymerase chain reaction were used.

[Postprandial glyсеmia, body weight, and cardiovascular parameters in diabetes type 2 in metformin monotherapy].

Twenty-five patients with type 2 diabetes (DM-2) and its moderate initial decompensation (8.83±1.85%) were examined.

[Correlation Level of HbA1с and postprandial glycemia in type 2 diabetes in the oral glucose tolerance test].

A number of today's analytical methods for postprandial glycemia in the oral glucose tolerance test (OGTT) still remain to be substantiated. The standard OGTT using 75 g of glucose was performed in 42 type 2 diabetes mellitus (DM-2) patients who received diet therapy. The concentration of Hb A1c has been found to correlate with absolute levels of glycemia during 1- and 2-hour OGTT.

[Impaired glucose balance and seven diabetes mellitus subtypes detected by intravenous glucose tolerance test].

A new clinically suitable method has been developed to calculate the rate of blood glucose elimination and hepatic glucose production (HGP) by the results of intravenous glucose tolerance test (IGTT). A subpopulation of non-diabetic persons was identified in whom substantially increased HGP is compensated for high blood glucose elimination, which prevents the development of hyperglycemia in them. This abnormality is designated impaired glucose balance and may be referred to as an early prehyperglycemic stage of diabetes (prediabetes).