Phytochemical Profiling and Bioactivity Assessment of L. Essential Oil and Extracts: Experimental and In Silico Insights.

L., a member of the Lamiaceae family, is widely used in traditional medicine for its therapeutic properties. This study aims to analyze the chemical composition of its essential oil and extracts, evaluate their antimicrobial and antioxidant activities, and investigate the interactions of their bioactive compounds with biological targets using in silico methods to better understand their mechanisms of action.

Facile Preparation Route of Cellulose-Based Flame Retardant by Ball-Milling Mechanochemistry.

In this study, a sustainable cellulose-based flame-retardant additive was developed, characterized, and incorporated into polypropylene (PP). Microcrystalline cellulose (Cel) was chemically modified with PO using the solvent-free ball-milling mechanochemistry approach at room temperature. This modification enabled phosphorus grafting onto cellulose, significantly enhancing the cellulose charring ability and improving the thermal stability of the char as revealed by thermogravimetric analysis (TGA).

Relationship Between Elastic, Chemical, and Thermal Properties of SiO Flint Aggregate.

Understanding the relationship between elastic, chemical, and thermal properties is essential for the prevention of the behavior of SiO flint aggregates during their application. In fact, the elastic properties of silica depend on chemical and heat treatment. In order to identify the crystallite sizes for natural SiO before and after chemical treatment samples, Williamson-Hall plots and Scherer's formulas are used.

Dung Beetles, Dung Burial, and Plant Growth: Four Scarabaeoid Species and Sorghum.

This study examined the impact of dung beetles on both sorghum growth and the physico-chemical properties of the soil over a two-month period. Four dung beetle species (, subsp. , , and ) were introduced into experimental setups, consisting of containers filled with sterilised clay-loam soil, with three treatment groups: [cow dung + beetles], [cow dung only], and a control group (no dung nor beetles), in order to evaluate their effects on various growth parameters, including the plant height, biomass, leaf area, and chlorophyll concentration.

How Does the Context Shape the Technical Support from the Provincial Health Administration to District Health Management Teams in the Democratic Republic of Congo? A Realist Evaluation.

Since 2014, the health sector in the Democratic Republic of the Congo has been undergoing reforms aimed at strengthening the Provincial Health Administration (PHA) to better support health district development through technical support to district health management teams (DHMTs). However, there is limited understanding of how, for whom, and under what conditions this support works. Using a realist evaluation approach, this study aimed to test an initial program theory of technical support to DHMTs by PHA staff in Kasai Central Province.

Quantification of Minerals in Edible Mushrooms via Optimized Microwave-Assisted Digestion: Nutritional Contributions of Fe, Mg, Na, K, and Ca.

The intake of mushrooms provides numerous beneficial properties for the correct functioning of the human body due to their rich content in carbohydrates, proteins, fibers, vitamins, and minerals. However, most of the reports are focused on the determination of bioactive compounds and only a few regarding the essential mineral content and the evaluation of the RDI. Thus, the aim of this study was to determine the mineral composition of different cultivated ( and ) and wild edible mushrooms (, , , , , and ) collected in the south of Spain and north of Morocco.

Metachromatic Leukodystrophy in Morocco: Identification of Causative Variants by Next-Generation Sequencing (NGS).

(1) Background: Most rare disease patients endure long delays in obtaining a correct diagnosis, the so-called "diagnostic odyssey", due to a combination of the rarity of their disorder and the lack of awareness of rare diseases among both primary care professionals and specialists. Next-generation sequencing (NGS) techniques that target genes underlying diverse phenotypic traits or groups of diseases are helping reduce these delays; (2) Methods: We used a combination of biochemical (thin-layer chromatography and high-performance liquid chromatography-tandem mass spectrometry), NGS (resequencing gene panels) and splicing assays to achieve a complete diagnosis of three patients with suspected metachromatic leukodystrophy, a neurologic lysosomal disorder; (3) Results: Affected individuals in each family were homozygotes for harmful variants in the gene, one of them novel (c.854+1dup, in family 1) and the other already described (c.

The Thermodynamics of the Van Der Waals Black Hole Within Kaniadakis Entropy.

In this work, we have studied the thermodynamic properties of the Van der Waals black hole in the framework of the relativistic Kaniadakis entropy. We have shown that the black hole properties, such as the mass and temperature, differ from those obtained by using the the Boltzmann-Gibbs approach. Moreover, the deformation κ-parameter changes the behavior of the Gibbs free energy via introduced thermodynamic instabilities, whereas the emission rate is influenced by κ only at low frequencies.

Evidences on the Use of Hypofractionation in Postoperative/Salvage Radiotherapy for Prostate Cancer: Systematic Review of the Literature and Recent Developments.

Background: Radical prostatectomy (RP) is one possible curative treatment for localized prostate cancer. Despite that, up to 40% of patients will later relapse. Currently, post-operative radiotherapy (PORT) courses deliver 1.

Insights into the Biotic Factors Shaping Ectomycorrhizal Associations.

Ectomycorrhizal (EM) associations are essential symbiotic relationships that contribute significantly to the health and functioning of forest ecosystems. This review examines the biotic factors that influence EM associations, focusing on plant and fungal diversity, host specificity, and microbial interactions. Firstly, the diversity of host plants and ectomycorrhizal fungi (EMF) is discussed, highlighting how the richness of these organisms affects the formation and success of EM symbioses.

Genetic Assessment of a Captive Population of Eurasian Stone-Curlew (), Source for the Reinforcement of Wild Populations.

Although ex situ conservation programs are increasingly valuable support tools for in situ conservation measures, success depends on these captive individuals to be genetically representative of the recipient population. The Eurasian stone-curlew () inhabit steppes that represent some of the most degraded and exploited habitats worldwide. A captive breeding program was implemented in Morocco as a pre-emptive effort for the conservation of the North African subspecies .

Longitudinal Follow-Up of Clinical Superficial Ovine Caseous Lymphadenitis.

Caseous lymphadenitis is an infectious disease that has a significant economic impact on sheep breeding. The objectives of this study were to evaluate the effect of season, animals' age, sex, body score and shearing on the clinical incidence of caseous lymphadenitis, relapses and abscess location in sheep from Settat province, Morocco. In this longitudinal study, 274 clinically healthy sheep were recruited in six flocks among 1451 inspected sheep and followed during 12 months to cover four seasons.

Genetic Analysis of Days Open in Moroccan Holstein Using Different Models to Account for Censored Data.

Reproductive efficiency is a key element of profitability in dairy herds. However, the genetic evaluation of fertility traits is often challenged by the presence of high censorship rates due to various reasons. An easy approach to address this challenge is to remove the censored data from the dataset.

Multilocular cystic nephroma in a young adult: A case report and review of literature.

Introduction: Multilocular cystic nephroma is an uncommon condition with only few cases described in the literature, although its benign nature is well-recognized.

Case Presentation: We present a case of a 28-year-old male patient who presented with a right flank pain, imaging suspected a multicystic renal cell carcinoma. A radical nephrectomy was performed view the size of the cyst and the high tumor complexity, which histology confirmed the diagnosis of multilocular cystic nephroma.

Investigation of and in Pakistan, with notes on the detection of tickborne Rickettsiales.

There is limited information on the occurrence of and ticks, as well as associated and species in Pakistan. Addressing this knowledge gap, the current study aimed at morphomolecular confirmation of these ticks and molecular assessment of associated Rickettsiales bacteria (, and spp.) in Balochistan, Pakistan.

Evaluation of the anti-spasmodic activity of essential oils of fruits and its main chemical component "perillaldehyde" on intestinal smooth muscle contractions of rodents: and approaches.

Ethnopharmacological Relevance: In Moroccan traditional medicine, plants from the Apiaceae family are widely utilized in folk medicine to treat various diseases associated with the digestive system. plays an important role as an antispasmodic that has been traditionally used, especially to treat digestive tract diseases in children.

Aim Of The Study: The aim of this research was to verify the traditional use by assessing the relaxant and spasmolytic activities of essential oil (ALEO) and then comparing them to the effects and potency of the major constituent of ALEO, which is perillaldehyde.

Evaporation-Induced Reticular Growth of UiO-66_NH in Chitosan Films: Adsorption of Iodine.

Metal-organic frameworks (MOFs) combined with polymers as hybrid materials offer numerous advantages such as enhanced performances through synergistic effects at their interface. The primary challenge in developing polymer/MOF hybrid matrix films is ensuring optimal dispersion and strong adhesion of crystalline MOFs to the polymer without aggregation, weak interaction, or phase separation. In this study, hierarchically porous UiO-66_NH/chitosan (ZrCSx-) films were designed by crystallizing UiO-66_NH within a chitosan (CS) skeleton.

The identification of a SARs-CoV2 S2 protein derived peptide with super-antigen-like stimulatory properties on T-cells.

Severe COVID-19 can trigger a cytokine storm, leading to acute respiratory distress syndrome (ARDS) with similarities to superantigen-induced toxic shock syndrome. An outstanding question is whether SARS-CoV-2 protein sequences can directly induce inflammatory responses. In this study, we identify a region in the SARS-CoV-2 S2 spike protein with sequence homology to bacterial super-antigens (termed P3).

Development of stable and porous AgO-loaded hydroxyapatite nanocomposites for enriched photocatalytic degradation of Rhodamine B under visible light.

A simple and inexpensive process from natural phosphate in the presence of Ag ions was used to develop AgO-loaded hydroxyapatite nanocomposites. The structural and textural characterization of the nanocomposites suggests that the AgO nanoparticles are well dispersed on the hydroxyapatite (HAp). The prepared nanocomposites show efficient Rhodamine B (RhB) dye photocatalytic degradation in water under visible and UV-visible light irradiation.

Green-synthesized silver nanoparticle-enhanced nanofiltration mixed matrix membranes for high-performance water purification.

This study presents the fabrication and characterization of mixed matrix membranes (MMMs) incorporating green-synthesized silver nanoparticles (AgNPs) using Hibiscus Rosa sinensis extract within a polyethersulfone (PES) matrix for nanofiltration (NF) application. The membranes were evaluated for their pure water permeability, salt rejection, dye removal, and antifouling performance. Results showed that the membrane with 0.

Learning Clinical Reasoning in Forensic Medicine: A Scoping Review.

Background: This scoping review aimed to explore the existing literature on teaching clinical reasoning in the field of forensic medicine.

Methods: The scoping review was conducted following the PRISMA extension for scoping reviews.

Results: The initial search yielded a total of 98 articles, of which 40 studies met the inclusion criteria.

Rare nonsyndromic multiple supernumerary and permanent impacted teeth in a young female patient: A case report.

Teeth, either erupted or impacted, that exceed the normal count are known as supernumerary teeth. They can appear unilaterally or bilaterally, singly or in multiples, and may be located anywhere in both dental arches. Multiple permanent impacted supernumerary teeth are uncommon and are often associated to syndromes but can be idiopathic.