69 results match your criteria: "Moriyama Memorial Hospital[Affiliation]"
J Cardiol
January 2025
Saitama Inst. of Public Health, Saitama, Japan.
Background: The social burden of nursing care is increasing with age, particularly for patients with heart failure who often require intensive care. This study aimed to clarify the relationship between nursing care needs and the clinical status of patients with a history of cardiovascular disease, focusing on the benefits of cardiac rehabilitation (CR) in reducing these needs.
Methods: This single-gate, multicenter, retrospective observational study included patients of all ages with a history of hospitalization for cardiovascular diseases using government-administered insurance claims and health examination data.
Background: Hypertension is a risk factor for bleeding events and is included in the HAS-BLED (Hypertension, Abnormal renal/liver function, Stroke, Bleeding history or predisposition, Labile INR, Elderly, Drugs/Alcohol concomitantly)score. However, the effects of blood pressure (BP) and changes in BP on bleeding events in patients undergoing percutaneous coronary intervention (PCI) remain poorly understood. This study is aimed to investigate the relationship between systolic BP (SBP) changes during hospitalisation and bleeding events in patients undergoing PCI.
View Article and Find Full Text PDFArch Phys Med Rehabil
October 2024
Department of Physical Therapy, Faculty of Rehabilitation Sciences, Sendai Seiyo Gakuin University, Sendai, Miyagi, Japan. Electronic address:
Objective: To investigate the recovery processes of pusher behavior (PB) and unilateral spatial neglect (USN) based on the severity of PB and USN, and to determine the relationship between activities of daily living (ADL) independence levels.
Design: This retrospective study aimed to examine the temporal changes and their association with ADL independence levels based on the severity of PB and USN.
Setting: Recovery ward of Moriyama Neurological Center Hospital between March 2017 and October 2022.
iScience
November 2024
Department of Molecular Diagnosis, Graduate School of Medicine, Chiba University, Chiba, Japan.
Craniopharyngiomas, including adamantinomatous (ACP) and squamous papillary (PCP) types, are challenging to treat because of their proximity to crucial pituitary structures. This study aimed to characterize the cellular composition, tumor tissue diversity, and cell-cell interactions in ACPs and PCPs using single-cell RNA sequencing. Single-cell clustering revealed diverse cell types, further classified into developing epithelial, calcification, and immune response for ACP and developing epithelial, cell cycle, and immune response for PCP, based on gene expression patterns.
View Article and Find Full Text PDFThe Japanese Society of Hypertension have established a blood pressure (BP) target of 130/80 mmHg for patients with coronary artery disease (CAD). We evaluated the data of 8793 CAD patients in the Clinical Deep Data Accumulation System database who underwent cardiac catheterization at six university hospitals and the National Cerebral and Cardiovascular Center (average age 70 ± 11 years, 78% male, 43% with acute coronary syndrome [ACS]). Patients were divided into two groups based on whether or not they achieved the guideline-recommended BP of <130/80 mmHg.
View Article and Find Full Text PDFNMC Case Rep J
July 2024
Department of Neurosurgery, Nagoya University, Nagoya, Aichi, Japan.
Front Endocrinol (Lausanne)
June 2024
Hypothalamic and Pituitary Center, Moriyama Memorial Hospital, Tokyo, Japan.
Objective: Postoperative nonfunctioning pituitary tumor (NFPT) regrowth is a significant concern, but its predictive factors are not well established. This study aimed to elucidate the pathological characteristics of NFPTs indicated for reoperation for tumor regrowth.
Methods: Pathological, radiological, and clinical data were collected from patients who underwent repeat operation for NFPT at Moriyama Memorial Hospital (MMH) between April 2018 and September 2023.
Acta Neurochir (Wien)
May 2024
Department of Hypothalamic and Pituitary Surgery, Toranomon Hospital, Minato-Ku, Tokyo, Japan.
Purpose: The aim of this study was to evaluate the treatment outcomes of neuroendoscopic cyst partial resection (ECPR) combined with stereotactic radiotherapy (SRT) for cystic craniopharyngiomas.
Methods: In this retrospective study, 22 craniopharyngioma patients undergoing ECPR combined with SRT were included. This combination therapy was indicated for suprasellar cystic craniopharyngiomas in patients whose pituitary function was preserved but would be difficult to preserve in direct surgery.
Healthcare (Basel)
April 2024
Department of Rehabilitation Medicine, Hokkaido University Hospital, Sapporo 060-8648, Japan.
In clinical practice, patient assessments rely on established scales. Integrating data from these scales into the International Classification of Functioning, Disability, and Health (ICF) framework has been suggested; however, a standardized approach is lacking. Herein, we tested a new approach to develop a conversion table translating clinical scale scores into ICF qualifiers based on a clinician survey.
View Article and Find Full Text PDFEndocrinol Diabetes Metab Case Rep
January 2024
Department of Endocrinology and Metabolism, National Hospital Organization Kyoto Medical Center, Kyoto, Japan.
Summary: Functioning gonadotroph tumors are rare neoplasms that can cause ovarian hyperstimulation syndrome (OHSS) in women of reproductive age. Here, we present a case of a follicle-stimulating hormone (FSH)-producing pituitary neuroendocrine tumor (PitNET) with irregular menstrual cycles and OHSS in a Japanese woman. A 34-year-old woman with bilateral multi-cystic ovarian mass was referred to our hospital for ovarian surgery.
View Article and Find Full Text PDFEndocrinology
February 2024
Division of Diabetes and Endocrinology, Department of Internal Medicine, Kobe University Hospital, Kobe, 650-0017, Japan.
Case Rep Hematol
December 2023
Department of Hematology, Saitama Cancer Center, Saitama, Japan.
J Clin Endocrinol Metab
February 2024
Department of Endocrinology and Metabolism, Toranomon Hospital, Tokyo, 105-8470, Japan.
Context: Desmopressin orally disintegrating tablets (ODTs) are widely used to treat arginine vasopressin deficiency (AVP-D). However, limited information is available on the dosage regimen; the dosage for each patient is selected based on their response to the initiation dose.
Objective: To investigate the relationships between clinical characteristics and the daily dose of ODTs and to identify factors that affect ODT dosages.
Brain Tumor Pathol
October 2023
Department of Pathology, Moriyama Memorial Hospital, Tokyo, 134-0081, Japan.
Epilepsia Open
December 2023
Department of Neurosurgery, Tokyo Women's Medical University, Shinjyuku, Japan.
A 62-year-old female experienced an extensive cerebral contusion in the left frontotemporal lobe due to an acute subdural hematoma at the age of 44 years. Six months after the injury, the patient developed epileptic seizures. The seizures were generalized with right cervical rotation and fencing posture.
View Article and Find Full Text PDFEndocr Pathol
December 2023
Department of Pathology, University of Wisconsin-Madison, Madison, WI, USA.
Clin Case Rep
August 2023
Department of General Medicine Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences Okayama Japan.
Octreotide is used in patients with insulinomas to treat hypoglycemia, and somatostatin receptor (SSTR) 2 expression is important for its efficacy. We report a case of insulinoma in a 50-year-old woman that responded to an octreotide test, showed accumulation in somatostatin scintigraphy, and was positive for SSTR2A on immunostaining.
View Article and Find Full Text PDFJ Neurosurg
December 2023
1Hypothalamic and Pituitary Center, Moriyama Memorial Hospital, Tokyo.
Proc Natl Acad Sci U S A
July 2023
Stem Cell Therapy Laboratory, Advanced Research Institute, Tokyo Medical and Dental University (TMDU), Bunkyo-ku, Tokyo 113-8510, Japan.
Stem Cell Reports
August 2023
Department of Endocrinology and Diabetes, Graduate School of Medicine, Nagoya University, Nagoya, Aichi 466-8550, Japan.
Pituitary organoids are promising graft sources for transplantation in treatment of hypopituitarism. Building on development of self-organizing culture to generate pituitary-hypothalamic organoids (PHOs) using human pluripotent stem cells (hPSCs), we established techniques to generate PHOs using feeder-free hPSCs and to purify pituitary cells. The PHOs were uniformly and reliably generated through preconditioning of undifferentiated hPSCs and modulation of Wnt and TGF-β signaling after differentiation.
View Article and Find Full Text PDFBrain Tumor Pathol
July 2023
Department of Hypothalamic and Pituitary Surgery, Toranomon Hospital, Tokyo, 105-8470, Japan.
Pituitary neuroendocrine tumors (PitNETs) lacking lineage affiliation are termed "null cell" PitNETs (NCTs). NCTs are characterized as being immunonegative for pituitary hormones as well as transcription factors. We analyzed the ultrastructure and immunohistochemistry of six hormone-negative and transcription factor (TPIT, PIT1, SF1)-negative PitNETs, with less than 1% immunoreactive cells.
View Article and Find Full Text PDFClin J Gastroenterol
August 2023
Department of Pathology, Saitama Cancer Center Hospital, 780 Komuro Inamachi, Kitaadachi-Gun, Saitama, 362-0806, Japan.
Front Cardiovasc Med
January 2023
Department of Cardiovascular Medicine, The University of Tokyo Hospital, Tokyo, Japan.
Background: This study evaluated the safety and effectiveness of alirocumab in Japanese patients with familial hypercholesterolemia (FH) or non-FH in a real-world clinical setting.
Methods and results: This post-marketing surveillance study had a 2-year standard observation period. The study included Japanese patients with hypercholesterolemia who were treatment naïve to alirocumab, had a high risk of developing cardiovascular events, and had an insufficient response to, or were unsuitable for, treatment with 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors.