1,365 results match your criteria: "Mongolian National University of Medical Sciences[Affiliation]"

Childhood burn injury in the ger districts of Ulaanbaatar, Mongolia: an analysis of parent narratives.

Int J Inj Contr Saf Promot

December 2024

Department of Public Health Sciences, Faculty of Health Sciences, Queen's University, Kingston, Ontario, Canada.

Childhood burns pose a significant public health concern, particularly in low- and middle-income nations, where the burden is pronounced. Mongolia stands out for its elevated rates of burn-related child mortality, especially among 1 to 5-year-olds. Despite this, there is a lack of research on the current status of childhood burns in Ulaanbaatar.

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Progression of Chest X-ray Findings of Silicosis Among Fluorspar Miners and Prognostic Factors: Retrospective Cohort Study in Mongolia.

J Occup Environ Med

November 2024

From the Department of Health Informatics, Kyoto University School of Graduate School of Medicine and School of Public Health, Kyoto, Japan (D.K., Y.N., M.T., Y.T., T.N.); Occupational Disease Clinic, Occupational Safety and Health Center, Ulaanbaatar, Mongolia (N.B., M.L.); Department of Pulmonology and Allergology, School of Medicine, Mongolian National University of Medical Sciences, Ulaanbaatar, Mongolia (I.D.).

Article Synopsis
  • The study investigated how silicosis, a lung disease, progresses in fluorspar miners after they stop being exposed to dust, including factors that might influence this progression.
  • A total of 67 former miners were studied over 19 years, analyzing their radiological images to track changes in lung health and using statistical models to identify significant risk factors.
  • Results showed that 75% of participants experienced disease progression, with older age and higher initial lung opacity linked to more severe disease worsening over time.
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Article Synopsis
  • The 5-(3'-Indolyl)oxazole moiety is a significant heterocyclic structure found in many natural products and has been linked to various biological activities, making it a focus for synthetic chemists.
  • This review covers the biological effects and synthetic methods of this scaffold from 1963 to 2024, emphasizing its potential as a lead compound in developing drugs for cancer, antimicrobial, antiviral, and other therapeutic uses.
  • It also discusses the mechanisms through which these compounds act in animal studies and suggests future directions for research on the 5-(3'-indolyl)oxazole scaffold.
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The phenomenon of lithic miniaturization during the Late Pleistocene at times coincided with increased artifact standardization and cutting edge efficiency-likely reflecting the use of small, sharp artifacts as interchangeable inserts for composite cutting tools and hunting weapons. During Marine Isotope Stage 2, Upper Paleolithic toolmakers in northern East Asia specifically used pressure techniques to make small, highly standardized lithic artifacts called microblades. However, little is currently known about how microblades affected the cutting edge efficiency of the toolkits they were a part of.

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The family Convolvulaceae comprises approximately 50-60 genera with approximately 1600-1700 species, exhibiting a rich diversity of morphological characteristics and occupying a broad range of ecological habitats. High-throughput sequencing identified a tentative new virus in the family Geminiviridae infecting Calystegia sepium var. japonica in South Korea.

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Urban expansion has been rapidly increasing and is projected to be tripled in 2030 in worldwide. The impact of urbanization has adverse effects on the environment and economic development. Residential lands consist of almost one-third of the urban area and heavily affect the city's inhabitants.

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Background: Accurate detection of kidney damage is key to preventing renal failure, and identifying biomarkers is essential for this purpose. We aimed to assess the accuracy of miRNAs as diagnostic tools for chronic kidney disease (CKD).

Methods: We thoroughly searched five databases (MEDLINE, Web of Science, Embase, Scopus, and CENTRAL) and performed a meta-analysis using R software.

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Impact of cross-reactivity and herd immunity on SARS-CoV-2 pandemic severity.

Infect Dis (Lond)

October 2024

Department of Neurology, NYU Langone Health, New York, New York, USA.

Public health systems reported low mortality from severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in East Asia, in low-income countries, and for children during the first year of the SARS-CoV-2 pandemic. These reports led commentators to suggest that cross-reactive immunity from prior exposure to other pathogens reduced fatality risk. Resolution of initial infection waves also contributed to speculation that herd immunity prevented further waves prior to vaccination.

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Achalasia, a rare esophageal motility disorder characterized by the inability of the lower esophageal sphincter to relax and loss of esophageal peristalsis, significantly impacts pediatric patient quality of life through symptoms like dysphagia, chest pain, and weight loss. This nationwide retrospective cohort study evaluates the efficacy and safety of peroral endoscopic myotomy (POEM) for pediatric achalasia in Mongolia, contributing to the limited global data on this minimally invasive treatment in children. Conducted between February 2020 and March 2022 at 2 tertiary centers, the study included symptomatic achalasia patients, treatment-naive or those with unsatisfactory outcomes from previous esophageal dilations.

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Article Synopsis
  • Esculetin (ESC) is a natural compound used in traditional Chinese medicine that helps protect the brain during strokes.
  • The study found that ESC helps reduce brain damage and improve behavior in mice after a stroke by affecting a protein called CKLF1.
  • Blocking CKLF1 with ESC also lowers the number of immune cells that can cause more damage, showing that it could be a good treatment for strokes in the future.
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  • A study assessed the long-term effects of the 13-valent pneumococcal conjugate vaccine (PCV13) on pneumococcal carriage in infants and toddlers in Asia, with surveys conducted before (2015) and after (2017, 2022) its introduction.
  • The findings revealed a decrease in carriage of PCV13 serotypes and a drop in resistance genes among toddlers six years after the vaccine was introduced, although overall pneumococcal density increased.
  • The most common non-vaccine serotype identified in 2022 was Serotype 15A, mainly linked to a specific genetic lineage, suggesting that tracking these changes is vital for future vaccine development.
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Objective: We aimed to update data on the morbidity and mortality rate of colorectal cancer (CRC) among the population of Mongolia by province between 2018 and 2022.

Methods: This study was designed using a descriptive method. The data were collected from 21 general hospitals of provinces, 9 general hospitals of districts, and the National Cancer Center in 2018-2022.

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Objectives: Rheumatoid arthritis (RA) seriously affects the daily life of people. The whole plant of Artemisia ordosica Krasch. (AOK) has been used in folk medicine.

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Functional characterization of sesquiterpene synthase in Mongolian medicine Syringa oblata in heartwood formation.

Plant Physiol Biochem

September 2024

State Key Laboratory for Quality Ensurance and Sustainable Use of Dao-di Herbs, National Resource Center for Chinese Materia Medica, China Academy of Chinese Medical Sciences, Beijing, 100700, China. Electronic address:

Lilac (Syringa oblata) is a well-known horticultural plant, and its aromatic heartwood is widely utilized in Traditional Mongolian Medicine for treating angina. However, limited research on the dynamic changes and mechanisms of aromatic substance formation during heartwood development hinders the analysis and utilization of its medicinal components. In this study, volatile metabolome analysis revealed that sesquiterpenes are the primary metabolites responsible for the aroma in heartwood, with cadinane and eremophilane types being the most prevalent.

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Epicardial adipose tissue in patients with systemic sclerosis.

Eur Heart J Imaging Methods Pract

September 2023

Department of Cardiology, Leiden University Medical Center, Albinusdreef 2, Leiden 2333 ZA, The Netherlands.

Aims: Epicardial adipose tissue (EAT) has emerged as a mediator between systemic inflammatory disorders and cardiovascular disease, and may therefore play a role in the pathophysiology of cardiac involvement in systemic sclerosis (SSc). The aim of this study was to assess the correlation between EAT and left ventricular (LV) function, and to determine the prognostic value of EAT in patients with SSc.

Methods And Results: Consecutive patients with SSc who underwent non-contrast thorax computed tomography and echocardiography were included.

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Hepatitis B surface antigen loss in chronic hepatitis B patients with low-viral-load.

J Gastroenterol Hepatol

November 2024

PhD Program of Environmental and Occupational Medicine and Graduate Institute of Clinical Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan.

Background And Aim: Among low viral load (DNA of hepatitis B virus (HBV) was < 2000 IU/mL), the factor of the loss of hepatitis B surface antigen (HBsAg) remained elusive.

Methods: The retrospective study recruited patients with chronic hepatitis B (CHB) who were negative low for hepatitis B e-antigen (HBeAg), had a low viral load, and experienced HBsAg loss during follow-up. CHB patients with low-viral load but without consequent HBsAg loss were also enrolled at the ratio of 1:4.

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Background: Mongolia introduced liver transplantation 10 years ago, becoming the 46th country globally to successfully perform this procedure. However, the cost of liver transplantation treatment remains expensive in Mongolia, a lower-middle-income country. Thus, the need to calculate the cost of liver transplants, a highly-valued treatment, forms the basis for this study.

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Background: Hepatocellular carcinoma (HCC) is the most common cancer in Mongolia. The relative importance of hepatitis B virus (HBV) and hepatitis C virus (HCV) infections in HCC etiology is known to vary greatly from one part of the world to another. Principally, 95% of HCC patients have chronic viral hepatitis, including 53% hepatitis B virus, 38.

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Ancient genomic analysis of a Chinese hereditary elite from the Northern and Southern Dynasties.

J Genet Genomics

July 2024

Institute of Archaeological Science, Fudan University, Shanghai 200433, China; Ministry of Education Key Laboratory of Contemporary Anthropology, Department of Anthropology and Human Genetics, School of Life Sciences, Fudan University, Shanghai 200433, China; Center for the Belt and Road Archaeology and Ancient Civilizations, Shanghai 200433, China; MOE Laboratory for National Development and Intelligent Governance, Fudan University, Shanghai 200433, China. Electronic address:

China's Northern and Southern Dynasties period (3rd-6th centuries AD) marked a significant era of ethnic integration in northern China. However, previous ancient DNA studies have primarily focused on northern ethnic groups, with limited research on the genetic formation of the hereditary elite family, especially considering their abundant archaeological record and clear material identity. In this study, we obtained the ancient genome of a hereditary elite family, Gao Bin (, 503 AD-572 AD), at 0.

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Objective: Epilepsy is a prevalent neurological disorder in the pediatric population, often accompanied by comorbidities, drug-related burdens, and psychosocial issues. Emotional intelligence (EI) is a crucial aspect of neurocognitive functioning that may be impaired in various clinical conditions. This study aimed to assess EI and its associated risk factors in children with epilepsy.

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Knowledge and attitude of traumatic dental injuries in Mongolian schoolteachers.

BMC Oral Health

July 2024

Department of Oral and Maxillofacial Surgery, School of Dentistry, Mongolian National University of Medical Sciences, Zorig street, P.O.Box-48/111, Ulaanbaatar, 14210, Mongolia.

Background: Traumatic dental injury (TDI) is a growing public health concern worldwide, and children and adolescents are commonly affected. Because TDI often occurs at school, the response of teachers to these injuries is crucial. However, teachers in various countries have been shown to lack knowledge of effective TDI first-aid response and need an intervention to improve their knowledge.

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Gut microbiome signatures associated with type 2 diabetes in obesity in Mongolia.

Front Microbiol

June 2024

Division of Systems Bioengineering, Department of Bioscience and Biotechnology, Faculty of Agriculture, Kyushu University, Fukuoka, Japan.

Mongolian people possess a unique dietary habit characterized by high consumption of meat and dairy products and fewer vegetables, resulting in the highest obesity rate in East Asia. Although obesity is a known cause of type 2 diabetes (T2D), the T2D rate is moderate in this population; this is known as the "Mongolian paradox." Since the gut microbiota plays a key role in energy and metabolic homeostasis as an interface between food and body, we investigated gut microbial factors involved in the prevention of the co-occurrence of T2D with obesity in Mongolians.

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Desertification is known to be a major threat to biodiversity, yet our understanding of the consequent decline in biodiversity remains insufficient. Here, we predicted climate change-induced range shifts and genetic diversity losses in three model dung beetles: Colobopterus erraticus, Cheironitis eumenes, and Gymnopleurus mopsus, distributed across the Gobi Desert and Mongolian Steppe, areas known for desertification. Phylogeographic analyses of mitochondrial COI sequences and species distribution modeling, based on extensive field investigations spanning 14 years, were performed.

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High-Efficiency Solar Transformation of Sugars via a Heterogenous Gallium(III) Catalyst.

Angew Chem Int Ed Engl

September 2024

School of Chemical and Biomolecular Engineering, University of Sydney, Darlington, NSW 2008, Australia.

Extremely limited research exploring the photocatalytic potential of main group metals, such as aluminum, gallium, and tin, has been undertaken due to their weak light harvesting properties. This study reports the efficient transformation of sugars to 5-hydroxymethylfurfural (HMF) with high yield employing an original heterogeneous photocatalyst comprising a gallium(III) complex immobilized on an alumina support. Under visible light irradiation, the reaction rate of HMF formation is ~143 times higher than the equivalent thermal reaction performed in the absence of light.

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