96 results match your criteria: "Mohammed V- Souissi University[Affiliation]"

Spondyloarthritis Associated with Uveitis: A Review.

Middle East Afr J Ophthalmol

October 2024

Department of Rheumatology, Faculty of Medicine and Pharmacy, Mohammed V Military Academic Hospital, Mohammed V-Souissi University, Rabat, Morocco.

Spondyloarthritis (SpA) is a group of chronic inflammatory rheumatism characterized by common clinical, radiological, and biological manifestations occurring on a predisposing genetic background dominated by the HLA-B27 antigen. Acute anterior uveitis is the most common extra-articular feature of SpA. The objective of this review is to describe the prevalence, demographic characteristics, factors favoring the occurrence of uveitis in patients with SpA, clinical manifestations, and their therapeutic management.

View Article and Find Full Text PDF
Article Synopsis
  • Lymphangiomas are rare, benign tumors linked mainly to congenital issues with lymphatic channels, with retroperitoneal types being particularly uncommon.
  • A 42-year-old woman experienced abdominal pain and was found to have a mass and uterine myoma, leading to surgical removal of both.
  • Proper diagnosis often requires histological examination despite CT scans helping with initial identification, and complete removal can lead to a cure, highlighting the importance of considering lymphangiomas in ovarian cyst diagnoses.
View Article and Find Full Text PDF

Adverse Effects of Gliptins in Type 2 Diabetics in Morocco.

Ann Afr Med

October 2024

Endocrinology Department, Faculty of Medicine and Pharmacy, Mohammed V Military Academic Hospital, Mohammed V-Souissi University, Rabat, Morocco.

Introduction: Gliptins are a relatively recent class of oral antidiabetic agents used in the treatment of type 2 diabetes. The aim of this study is to identify the adverse effects of gliptins in patients with type 2 diabetes, compare the tolerability of these drugs with data from the literature, and determine patients' behavior in the face of these adverse effects with a view to optimizing their management.

Methods: Our study is cross-sectional, descriptive, and analytical, involving 100 patients aged over 20 years, followed at the Endocrinology Department of the Military Hospital Mohammed V.

View Article and Find Full Text PDF

DNA polymerases are essential enzymes that play a key role in living organisms, as they participate in the synthesis and maintenance of the DNA molecule. The intrinsic properties of these enzymes have been widely observed and studied to understand their functions, activities, and behavior, which has allowed their natural power in DNA synthesis to be exploited in modern biotechnology, to the point of making them true pillars of the field. In this context, the laboratory evolution of these enzymes, either by directed evolution or rational design, has led to the generation of a wide range of new DNA polymerases with novel properties, suitable for a variety of biotechnological needs.

View Article and Find Full Text PDF
Article Synopsis
  • Hughes-Stovin syndrome (HSS) is a rare condition characterized by systemic vasculitis leading to both venous and arterial thrombosis, making it hard to differentiate from pulmonary embolism (PE) early on.
  • This study compared 40 HSS patients to 50 PE patients, analyzing demographics, clinical findings, and results from computed tomography pulmonary angiography (CTPA).
  • Results revealed that HSS patients were significantly younger and did not have co-morbidities like many PE patients; HSS showed unique vascular changes, including more frequent parenchymal hemorrhage and distinct pulmonary artery aneurysms.*
View Article and Find Full Text PDF

Morbidity and mortality conferences (MMCs) have evolved beyond their traditional educational role to become instrumental in enhancing patient safety. System-based MMCs offer a unique perspective on patient safety by dissecting systemic factors contributing to adverse events. This paper reviews the impact of MMC in managing postoperative bleeding after gastric and pancreatic cancer surgery, within the constraints of limited resources.

View Article and Find Full Text PDF

Acromegaly among a Moroccan population.

Pan Afr Med J

March 2024

Endocrinology Department, Mohammed V Military Academic Hospital, Faculty of Medicine and Pharmacy, Mohammed V-Souissi University, Rabat, Morocco.

Acromegaly is defined as an acquired dysmorphytic syndrome due to excessive secretion of growth hormone (GH) and consequently of insulin-like growth factor-1 (IGF-1). This is a retrospective study of patients who were hospitalized in the Endocrinology Department of the Mohammed V Military Academic Hospital in Rabat over a period of 14 years (2008 to 2022), reporting on their clinical, paraclinical and evolutionary profiles and comparing the results with the data in the literature. Nineteen patients were included in our study.

View Article and Find Full Text PDF

Thyroid autoimmunity in relation to HLA-DRB1 and HLA-DQB1 polymorphism in nonsegmental vitiligo: a cross-sectional-study.

Am J Transl Res

February 2024

Department of Dermatology, Faculty of Medicine and Pharmacy, Mohammed V Souissi University, Ibn Sina Hospital Rabat, Morocco.

Objectives: Nonsegmental vitiligo (NSV) is frequently associated with thyroid autoimmunity (TAI), however, the immunopathogenic mechanisms of such association remain to be investigated. The aims of this work were to estimate the frequency of TAI and to describe the genetic polymorphism in the human leukocyte antigen (HLA)-DRB1 and -DQB1 loci in TAI susceptibility among patients with NSV.

Patients And Methods: In this cross-sectional study, screening for TAI was performed in 97 Moroccan patients with NSV by measuring antibodies against thyroid peroxidase (TPOAb) and thyroglobulin (TGAb).

View Article and Find Full Text PDF

Introduction And Importance: Intra veinous leiomyomatosis (IVL) is one pathology of a known group of ectopic leiomyomatosis that gathers many entities all defined by the presence of benign tumours arising from uterine smooth muscle cells. The authors aim through this case report to address the underdiagnosis of IVL in pre-menopausal women and the potential confusion with other cardiac tumours.

Case Presentation: A 48-year-old woman initially treated for a suspected intracardiac myxoma underwent two surgeries.

View Article and Find Full Text PDF

Shoulder capsulitis: What relation with diabetes mellitus in a moroccan population?

Ann Afr Med

January 2023

Department of Endocrinology, Faculty of Medicine and Pharmacy, Mohammed V Military Academic Hospital, Mohammed V-Souissi University, Rabat, Morocco, North Africa.

Introduction: Shoulder capsulitis (SC) is a common musculoskeletal complication in patients with diabetes. It can be particularly disabling. It is often overlooked by clinicians.

View Article and Find Full Text PDF

Peutz-Jeghers syndrome is a rare genetic disorder characterized by hyperpigmented mucocutaneous macules, hamartomatous polyps of the small intestine, and family history. These hamartomatous polyps can cause intermittent abdominal pain, chronic anemia, or even intussusception. Imaging has an important role in the diagnosis of this syndrome but also in the identification of complications and periodic surveillance.

View Article and Find Full Text PDF

Von Recklinghausen disease is the most common phacomatosis. It can affect many systems, including the bone system. Through these 2 cases, we illustrate the bone manifestations of this disease.

View Article and Find Full Text PDF

Reidel's Thyroiditis, a Diagnostic and Management Challenge: A Case Report and Review of the Literature.

Case Rep Endocrinol

October 2021

Endocrinology Department, Mohammed V Military Academic Hospital, Faculty of Medicine and Pharmacy, Mohammed V-Souissi University, Rabat, Morocco.

Riedel's thyroiditis is a very rare inflammatory condition. It affects not only the thyroid gland but also the adjacent vital structures. It may also be associated with different forms of systemic fibrotic disorders.

View Article and Find Full Text PDF

Pulmonary vasculitis in Hughes-Stovin syndrome (HSS): a reference atlas and computed tomography pulmonary angiography guide-a report by the HSS International Study Group.

Clin Rheumatol

December 2021

Faculty of Behavioral, Management and Social Sciences, Department Psychology, Health and Technology, University of Twente, Drienerlolaan 5, 7522NB, Enschede, The Netherlands.

Introduction: Hughes-Stovin syndrome (HSS) is a systemic vasculitis characterized by widespread venous/arterial thrombosis and pulmonary artery aneurysms (PAAs), which is associated with serious morbidity and mortality. All fatalities reported in HSS resulted from unpredictable fatal suffocating hemoptysis. Therefore, it is necessary to recognize pulmonary complications at an early stage of the disease.

View Article and Find Full Text PDF

Lymphatic malformation or cystic lymphangioma is a benign tumour of the lymphatic vessels. It is more commonly reported among children and has polymorphic clinical presentations. The diagnosis is based on imaging but requires histological confirmation.

View Article and Find Full Text PDF

Background: Treatment advances have reduced the adverse events associated with hematopoietic stem cell transplant (HSCT) and led to an increased number of transplants performed. HSCT patients are living longer with concerns on long-term outcomes. Bone fragility and fracture are at the forefront for long-term morbidities post-HSCT.

View Article and Find Full Text PDF

Lemmel's syndrome is a rare and misdiagnosed cause of obstructive jaundice. The cause of the obstacle is a duodenal diverticulum located at the periampullary generating a compression effect on the common bile duct with secondary dilation of the extra- and intra-hepatic bile ducts. Late diagnosis of this entity is common and may lead to unnecessary further investigations and therapeutic delay.

View Article and Find Full Text PDF

A critical analysis of 57 cases of Hughes-Stovin syndrome (HSS). A report by the HSS International Study Group (HSSISG).

Int J Cardiol

May 2021

Faculty of Behavioral, Management and Social Sciences, Department Psychology, Health and Technology, University of Twente, Drienerlolaan 5, 7522NB Enschede, the Netherlands.

Background: Hughes-Stovin syndrome (HSS) is a systemic disease characterized by widespread vascular thrombosis and pulmonary vasculitis with serious morbidity and mortality. The HSS International Study Group is a multidisciplinary taskforce aiming to study HSS, in order to generate consensus recommendations regarding diagnosis and treatment.

Methods: We included 57 published cases of HSS (43 males) and collected data regarding: clinical presentation, associated complications, hemoptysis severity, laboratory and computed tomography pulmonary angiography (CTPA) findings, treatment modalities and cause of death.

View Article and Find Full Text PDF

Corrigendum to "Sedative and Hypnotic Activities of the Methanolic and Aqueous Extracts of from Morocco".

Adv Pharmacol Pharm Sci

November 2020

Laboratory of Pharmacology and Toxicology, Department of Drugs Sciences, Faculty of Medicine and Pharmacy, Mohammed V Souissi University, ERTP, BP 6203, Rabat Instituts, Agdal, Rabat, Morocco.

[This corrects the article DOI: 10.1155/2012/270824.].

View Article and Find Full Text PDF

Urinary schistosomiasis: report of case diagnosed in bladder biopsy.

BMC Clin Pathol

November 2018

Department of Pathology, Military General Hospital Mohammed V, Mohammed V- Souissi University, Hay Riad, 10000 Rabat, Morocco.

Background: Urinary schistosomiasis is a common parasitic disease in endemic countries.

Case Presentation: We report the case of a patient who was on a working trip to Mauritania. This parasitosis, suspected in the presence of hematuria and the notion of stay in an endemic zone, was confirmed by the presence of Schistosoma heamatobium eggs during the histological examination of the bladder biopsy performed after cystoscopy, highlighting a bilharzial granuloma and of course, the diagnosis was confirmed by the presence of eggs during the direct examination of the freshly collected urine.

View Article and Find Full Text PDF

Bone management in hematologic stem cell transplant recipients.

Osteoporos Int

December 2018

Department of Medicine, School of Clinical Sciences, Monash University, Clayton, Australia.

Autologous and allogeneic hematopoietic stem cell transplantation (HSCT) is the treatment of choice for patients with some malignant and non-malignant hematological diseases. Advances in transplantation techniques and supportive care measures have substantially increased the number of long-term HSCT survivors. This has led to an increasing patient population suffering from the late effects of HSCT, of which, bone loss and its consequent fragility fractures lead to substantial morbidity.

View Article and Find Full Text PDF

Musculoskeletal Disorders in Patients with Diabetes Mellitus: A Cross-Sectional Study.

Int J Rheumatol

June 2018

Rheumatology Department, Mohammed V Military Academic Hospital, Faculty of Medicine and Pharmacy, Mohammed V-Souissi University, Rabat, Morocco.

Introduction: A variety of musculoskeletal disorders (MS) have been associated with diabetes mellitus (DM). This study aimed at assessing the prevalence and associated factors of MS disorders in Moroccan diabetic patients.

Methods: A cross-sectional study enrolled consecutive patients with DM.

View Article and Find Full Text PDF

Late-onset choreoathetotic syndrome following heart surgery in adults with end-stage renal disease.

Saudi J Kidney Dis Transpl

October 2019

Department of Nephrology Dialysis and Renal Transplantation, Faculty of Medicine, Mohammed V Military Hospital, Mohammed V-Souissi University, Rabat, Morocco.

Choreoathetotic syndrome is a rare complication of open cardiac surgery that is seen usually in children after surgery for congenital cardiac anomalies. Here, we report two cases of adult patients with end-stage renal disease (ESRD) on regular hemodialysis who developed acute choreoathetotic syndrome few days after cardiac surgeries under cardiopulmonary bypass (CPB). Improvement was seen after an interval with complete resolution in one case.

View Article and Find Full Text PDF