Evaluation of the interaction between Menthol and Camphor, Major Compounds of Clinopodium nepeta Essential Oil: Antioxidant, Anti-inflammatory and Anticancer Activities against Breast Cancer Cell Lines.

This study evaluates the antioxidant, anti-inflammatory and anticancer activities of camphor, menthol and their equimolar combination. In silico toxicity analysis confirmed the absence of toxic effects for both compounds. Antioxidant activity, assessed by 1,1-diphenyl-2-picrylhydrazyl (DPPH) and 2,2'-azino-bis (3-ethylbenzothiazoline-6-sulfonic acid) (ABTS) assays, revealed a synergistic effect of the equimolar combination with IC50 values of 10.

Mycotic aortic aneurysm secondary to spondylodiscitis: A case report and review.

Mycotic aneurysms are a rare but potentially life-threatening complication of infections, particularly those involving the spine. Spondylodiscitis, a bacterial or fungal infection of the intervertebral disc, is a known risk factor for the development of mycotic aneurysms. Early diagnosis and prompt treatment are crucial for improving patient outcomes.

When hyperthyroidism goes unchecked: A rare case of cardiac tamponade induced by acute pericarditis in Graves' disease.

Graves' disease, the most prevalent cause of hyperthyroidism, is an autoimmune disorder associated with several cardiovascular complications. The occurrence of acute pericarditis within the context of Graves' disease, is very rare. We present an uncommon case of cardiac tamponade in a patient diagnosed with Graves' disease.

Abundant hemoptysis revealing an aneurysm of an aberrant systemic artery to the left lower pulmonary lobe: A case report.

Pulmonary sequestration (PS) is a congenital anomaly characterized by a lung region that is isolated from its normal bronchial and vascular connections. It typically receives blood supply from an aberrant systemic artery. An aneurysm of that aberrant artery is extremely rare.

Acute renal infarction mimicking renal colic: A case report and review of the literature.

Renal infarction is a rare pathology, which can be life-threatening for the kidney. Its low incidence and non-specific clinical manifestations make it difficult to diagnose, often resulting in delayed or misdiagnosis. Contrast-enhanced CT has a role to play in early positive diagnosis, enabling rapid and effective management.

Pharmaco-invasive Therapy: A Continued Role for Fibrinolysis in the Primary PCI era.

Introduction: Early Primary percutaneous coronary intervention (pPCI) is the preferred reperfusion therapy for most patients with ST-segment elevation myocardial infarction (STEMI), and the European guidelines recommend pPCI to occur within 120 min of first medical contact. However, this is not always available.

Methods: We performed a retrospective study of patients admitted for STEMI to a level I cardiac intensive care unit in a developing country, to analyze the efficacy of the pharmaco-invasive (PI) strategy versus late PCI over a 2-year follow-up.

The Benefit of an Extensive Cancer Screening Strategy After the First Episode of Unprovoked Pulmonary Embolism.

Introduction: The etiological assessment after an acute unprovoked pulmonary embolism (PE) represents an essential step in the overall management of the patient, with the aim of adapting the duration and type of anticoagulant to be used, avoiding recurrence and thus improving overall morbidity and mortality, but this is not such a simple question to answer.

Purpose: The main objective of this work is to know the benefit of a limited etiology strategy versus an extensive strategy after a first episode of acute non-provoked PE, first on all-cause mortality, and then the superiority of one strategy over another on the diagnosis of cancer at 1 year in patients admitted to a cardiac intensive care unit.

Methods: This is a single-center, retrospective study from 2014 to 2021, which includes all patients, admitted to a cardiac intensive care unit for a first episode, at high or high intermediate risk of mortality at day 30.

Prevalence of epilepsy in Morocco: A population-based study.

Objective: In Morocco, there was a lack of data related to the epidemiology of epilepsy. This data serves as a useful basis for the development of any national intervention or action program against epilepsy in Morocco. Through this study, we aimed to estimate the active and lifetime prevalence of epilepsy in Morocco.

Isolated dorsal dislocation of the distal radioulnar joint: A case report.

Isolated acute dislocation of the distal radioulnar joint is a rare lesion, and in 50 % of cases goes unrecognized; it may be palmar or dorsal. Its diagnosis is suspected when the wrist is traumatic, painful, with limited pronosupination and no fracture on radiological examination. Treatment is aimed at preventing the development of chronic instability and/or arthrosis, and consists of reduction followed by immobilization.

The Impact of Prior Antithrombotic use on Thromboembolic Events in Patients with Cardiovascular Disease and Severe COVID-19 Infection.

Objective: Our objective in this study was to determine the predictive factors of thromboembolic complications in patients with previous heart disease and severe covid-19 infection and the impact of previous use of antithrombotics on protection against these complications.

Methods: We conducted a single-center retrospective study of 158 patients with heart disease admitted to an intensive care unit for severe SARS-COV-2 infection. In order to determine the predictive factors, we used logistic regression analysis.

Pyogenic granuloma after burns: a case report and review of the literature.

Pyogenic granuloma (PG) is a benign vascular proliferative tumor of the skin and mucous membranes, it can appear spontaneously or following triggering factors. Different clinical aspects are described, pyogenic granulomas following burns (GB) are rare. We report a case of post-burn pyogenic granuloma confirmed by histological study and treated surgically.

Severe hypercalcemia complicated by acute pancreatitis revealing generalized bone lysis metastasis: Case report and review.

Malignant hypercalcemia is a frequent metabolic complication of osteophilic tumors, exceptionally revealing cavitary cancer, but its prognosis remains poor despite early and adequate management. We report the case of a young patient, smoker without any previous history, admitted for the management of a digestive symptoms made of abdominal pain with food vomiting. The patient had an electrocardiogram withchest computed tomography scan and BBC evoking PA on malignant hypercalcemia.

Purpura as a late complication of covid-19 infection that should not be ignored: Case report and brief review.

Introduction And Importance: The SARS COV2 infection is a challenging pandemic that has affected millions of people with a very high mortality rate. In addition to the typical respiratory symptoms, it can also cause variable skin lesions, such as vascular purpura in some exceptional cases.

Case Presentation: We report the case of a 60-year-old woman who was admitted for a SARS COV2 infection, the evolution was marked by the appearance of a vascular purpura at D20 after the beginning of the symptoms.

Multiple cranial nerve palsies revealing blast crisis in patient with chronic myeloid leukemia in the accelerated phase under nilotinib during severe infection with SARS-COV-19 virus: Case report and review of literature.

Since the introduction of tyrosine kinase inhibitors as primary therapy for patients with chronic myeloid leukemia (CML), the prognosis of these patients has improved significantly, and the number of patients who progress to the blast phase has decreased considerably. We report the case of a 35 year-old CML patient in accelerated phase treated with nilotinib, who presents a severe COVID-19 infection requiring non-invasive ventilation, and who subsequently presents a multiple cranial nerve palsy revealing a blast crisis of his CML. Multiple cranial nerve palsy is a sign of neurological involvement of CML in its blast phase.

Brainstem stroke: A fatal thromboembolic event after new onset atrial fibrillation during covid-19 infection: A case report and literature review.

Coronavirus disease (COVID-19) disease is a serious pandemic that put the world on an exceptional sanitary alert. It is a multifaceted disease, since it can affect the lung, the cardiovascular system and the central nervous system at the same time. A 66-year-old man, diabetic, hypertensive, admitted to the emergency room for medical management of acute dyspnea, diagnosed with COVID-19 infection.

Plasma exchange as treatment for acute fatty liver disease of pregnancy.

Acute fatty liver disease of pregnancy AFLP is an obstetrical emergency, with severe complications that may include death. Management of AFLP is challenging and include plasma exchange which helps to improve the prognosis for both mother and fetus and delay liver transplantation.

Delayed awakening from general anesthesia revealing Fahr syndrome: Case report and literature review.

Fahr syndrome (FS) is defined by the presence of bilateral and symmetrical intracerebral nonarteriosclerotic calcifications, localized in the central gray nuclei. We report the case of a patient who presented a postoperative delay in awakening and whose biological and radiological investigations revealed a FS.