Beyond the Bedside: Decoding Patient Profiles for Smarter Virtual Patient Observation.

Background: Emerging evidence suggests that virtual patient observation (VPO) may help promote patient safety.

Purpose: The purpose of this study was to examine and describe the demographic and clinical characteristics of patients who incurred VPO.

Methods: A retrospective analysis was conducted.

Patient-Reported Financial Burden of Treatment for Colon or Rectal Cancer.

Importance: The longitudinal experience of patients is critical to the development of interventions to identify and reduce financial hardship.

Objective: To evaluate financial hardship over 12 months in patients with newly diagnosed colorectal cancer (CRC) undergoing curative-intent therapy.

Design, Setting, And Participants: This prospective, longitudinal cohort study was conducted between May 2018 and July 2020, with time points over 12 months.

Duvelisib for Critically Ill Patients With Coronavirus Disease 2019: An Investigator-Initiated, Randomized, Placebo-Controlled, Double-Blind Pilot Trial.

Background: Despite improvements in prevention and treatment, severe coronavirus disease 2019 (COVID-19) is associated with high mortality. Phosphoinositide 3-kinase (PI3K) pathways contribute to cytokine and cell-mediated lung inflammation. We conducted a randomized, placebo-controlled, double-blind pilot trial to determine the feasibility, safety, and preliminary activity of duvelisib, a PI3Kδγ inhibitor, for the treatment of COVID-19 critical illness.

Early results of geometric ring annuloplasty for bicuspid aortic valve repair during aortic aneurysm surgery.

Objectives: Geometric ring annuloplasty has shown promise during bicuspid aortic valve repair for aortic insufficiency. This study examined early outcomes of bicuspid aortic valve repair associated with proximal aortic aneurysm replacement.

Methods: From September 2017 to November, 2021, 127 patients underwent bicuspid aortic valve repair with concomitant proximal aneurysm reconstruction.

Experiences of Master's Prepared Clinical Nurse Leaders at Three Years Post-Graduation.

Direct Entry Master of Science in Nursing programs that incorporate Clinical Nurse Leader (CNL) education are relatively new in the United States. Little is known about the transition to practice experience of Master's prepared CNL graduates. This evaluation explored how Direct Entry Master of Science in Nursing CNL graduates perceived their transition to practice experience three years post-graduation.

Awareness of cord blood collection and the impact on banking.

Background: Umbilical cord blood (UCB) is an important source of hematopoietic stem cells for transplantation especially in minority populations with limited chances of finding a histocompatible volunteer donor in the registry. UCB has the advantages of early availability, successful outcomes despite some histocompatibility mismatch, and low incidence of chronic graft-versus-host disease. Public cord blood banks that disseminate UCB products for transplant depend on voluntary donation at participating hospitals and obstetrical providers for collection.

Endovascular intervention for peripheral artery disease.

Advances in endovascular therapies during the past decade have broadened the options for treating peripheral vascular disease percutaneously. Endovascular treatment offers a lower risk alternative to open surgery in many patients with multiple comorbidities. Noninvasive physiological tests and arterial imaging precede an endovascular intervention and help localize the disease and plan the procedure.

Anabolic steroids and growth hormone.

Athletes are generally well educated regarding substances that they may use as ergogenic aids. This includes anabolic steroids and growth hormone. Fortunately, the abuse of growth hormone is limited by its cost and the fact that anabolic steroids are simply more enticing to the athlete.

Second-look laparoscopy adhesiolysis. The procedure of choice for preventing adhesion recurrence.

A study was designed to determine the efficacy of second-look laparoscopy adhesiolysis in preventing adhesion recurrence seven days after conservative microsurgical reconstructive surgery on the uterotuboovarian complex. Third-look laparoscopy was used to evaluate the second-look laparoscopy adhesiolysis 6-18 months later. It indicated that second-look laparoscopy adhesiolysis was beneficial in preventing adhesion recurrence.

Oculoplastic update.

Lacrimal tearing problems can be handled using a conservative approach by massage, antibiotic eye drops, nasal saline drops, and good hygienic care of the periorbital region. Cases in which preseptal inflammatory changes or marked exudated debris occur require early surgical intervention. Benign eyelid lesions can be identified in the majority of cases by clinical appearance.