Increased Zinc Availability Enhances Initial Aggregation and Biofilm Formation of .

Bacteria growing within biofilms are protected from antibiotics and the immune system. Within these structures, horizontal transfer of genes encoding virulence factors, and promoting antibiotic resistance occurs, making biofilms an extremely important aspect of pneumococcal colonization and persistence. Identifying environmental cues that contribute to the formation of biofilms is critical to understanding pneumococcal colonization and infection.

High-sensitivity fiber-loop ringdown evanescent-field index sensors using single-mode fiber.

We combine the evanescent-field scattering sensing mechanism with the fiber-loop ringdown detection scheme to create a new type of fiber optic index sensor using partially cladded single-mode fiber as a sensing element. A detection limit for an optical index change of 3.2x10(-5) is demonstrated in the initial examination by using certified refractive index oils and laboratory-made sodium chloride solutions.