2,136 results match your criteria: "Missed Abortion"

Ectopic pregnancies are uncommon among women presenting for abortion. However, where suspected, rapid referral for definitive diagnosis is essential to prevent harm. We assessed whether implementation of a standardised decision-making tool, an algorithmic representation of the clinical decisions and associated actions defined in policy, in a British abortion service was associated with a reduction in missed opportunities to escalate care where indicated.

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Background: Missed abortion in the first trimester is characterized by the cessation of embryonic or fetal development while the cervix remains closed, often resulting in little to no bleeding. Ultrasound examinations typically reveal an empty gestational sac or an embryo/fetus that lacks cardiac activity. Misoprostol is the primary medication used to manage early pregnancy loss.

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Arteriovenous malformations (AVMs) are abnormal vascular connections bypassing the capillary system, categorized as acquired or congenital. Acquired uterine AVMs, often resulting from uterine trauma due to procedures like dilatation and curettage, can be life threatening, necessitating prompt diagnosis and management. Here we present a 34-year-old woman with a history of missed abortion and dilatation and curettage presenting with abnormal uterine bleeding 2 months postprocedure.

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Article Synopsis
  • * A 32-year-old woman undergoing assisted reproductive technology showed two embryos with regular heartbeats and tightly entangled umbilical cords at 8.5 weeks gestation, identified through various ultrasound techniques.
  • * The findings suggest that UCE can be diagnosed as early as eight weeks of gestation, but may indicate a poor prognosis for the pregnancy.
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Background: Family planning (FP) is part of Ethiopia's essential health service package. However, integrating FP into other health care services is a relatively new concept. Integrated service can minimize missed opportunities and allow health workers to provide FP services and Reproductive, Maternal, Newborn, Child, Adolescent, and Nutrition (RMNCAH-N) services simultaneously.

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Association between exposure to per- and polyfluoroalkyl substances and missed miscarriage: A hospital-based case-control study in Shanghai, China.

Environ Toxicol Pharmacol

December 2024

Shanghai Key Laboratory of Maternal Fetal Medicine, Shanghai Institute of Maternal-Fetal Medicine and Gynecologic Oncology, Shanghai First Maternity and Infant Hospital, School of Medicine, Tongji University, Shanghai 200092, China. Electronic address:

Per- and polyfluoroalkyl substances (PFAS) are persistent environmental pollutants linked to reproductive disruptions. This study investigated the relationship between PFAS exposure and missed miscarriage in a hospital-based, case-control study in Shanghai, China. There were 393 women in our research, including 198 cases and 195 controls.

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Importance: Most US individuals who access abortion care pay out of pocket due to insurance coverage restrictions on abortion. More research is needed on the financial and psychological burdens of abortion seeking, particularly for those traveling across state lines for care.

Objectives: To estimate the proportion of patients seeking abortion who incur abortion-related catastrophic health expenditures (CHEs), assess whether CHE differs between those seeking care in state vs out of state, and examine the association of CHE with mental health symptoms.

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Autoimmune Condition Diagnosis Following Recurrent Pregnancy Loss.

Am J Reprod Immunol

October 2024

Department of Reproductive Biology, MetroHealth Division of Maternal Fetal Medicine, Cleveland, USA.

Problem: Research has suggested a link between recurrent pregnancy loss (RPL) and cell-mediated immunity dysregulation. We aimed to determine if a history of RPL is associated with diagnosis of a cell-mediated autoimmune condition (AIC).

Method Of Study: A retrospective cohort study was conducted using the TriNetX research network.

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Conventional radiography is widely used for postmortem foetal imaging, but its role in diagnosing congenital anomalies is debated. This study aimed to assess the effectiveness of X-rays in detecting skeletal abnormalities and guiding genetic analysis and counselling. This is a retrospective analysis of all post-abortion diagnostic imaging studies conducted at a centre serving a population of over 300,000 inhabitants from 2008 to 2023.

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Article Synopsis
  • * A case involving a 30-year-old woman revealed that after her D&C at 10 weeks due to missed abortion, she experienced severe abdominal pain and signs of internal bleeding, verified by imaging as a uterine perforation.
  • * Emergency surgery was performed to fix the perforation, leading to her full recovery; the case highlights the need for careful monitoring during and after D&C procedures to prevent significant health risks.
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Objective: To identify the relationship between white blood cell indices in missed miscarriage compared to ongoing pregnancy in the first trimester.

Methods: The diagnostic accuracy study was conducted at the Department of Maternity, Al-Yarmouk Hospital, Baghdad, Iraq, from January to October 2021,and comprised healthy first-trimester pregnant women in group A and those with missed miscarriage after 7-13 weeks of gestation in group B. Ultrasound findings and the last menstrual period were noted for all the subjects.

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Initially categorized 46,XY embryo transfer ending with 45,X products of conception-a case report and a review of discordant result management.

F S Rep

September 2024

Division of Reproductive Endocrinology and Infertility, Department of Obstetrics and Gynecology, University of Iowa, Iowa City, Iowa.

Objective: To report a case of an initially categorized euploid male embryo screened using preimplantation genetic testing (PGT) resulting in miscarriage and testing of products of conception consistent with Turner syndrome, and to discuss additional workup and considerations in cases of discrepancy.

Design: Case report.

Setting: University fertility clinic.

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Article Synopsis
  • The study aimed to compare the effectiveness and safety of non-mRNA vs. mRNA COVID-19 vaccines specifically for pregnant women and their newborns, using systematic reviews and meta-analysis methods.
  • After evaluating 4451 results, 16 studies were extensively reviewed, resulting in the analysis of 8 studies with 32,153 patients.
  • Findings showed non-mRNA vaccines had a higher incidence of fever but a lower incidence of fetal/neonatal death; however, the Jansen vaccine had higher rates of premature labor and miscarriages compared to the Pfizer vaccine.
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Article Synopsis
  • About 26% of pregnancies end in miscarriage, with many cases remaining unexplained despite known causes like chromosomal abnormalities and uterine issues.
  • A review of 27 studies involving over 134,000 patients examined various biochemical factors potentially linked to early pregnancy loss.
  • Current research suggests there is no definitive biochemical marker for predicting first-trimester pregnancy losses, highlighting the need for combined indicators or new assessment models like α-fetoprotein in vaginal blood.
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Background: Women's sexual and reproductive health needs are complex and vary across the life course. They are met by a range of providers, professionals and venues. Provision is not well integrated, with inequalities in access.

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High-risk factors for massive haemorrhage in medical abortion patients with missed miscarriage.

BMC Pregnancy Childbirth

September 2024

Department of Family Planning, School of Medicine, International Peace Maternity and Child Health Hospital, Shanghai Jiao Tong University, No. 910 Hengshan Road, Xuhui District, Shanghai, China.

Background: Recently, the incidence of missed miscarriage has gradually increased, and medical abortion is a common method to terminate a pregnancy. In the process of medical abortion, massive vaginal bleeding takes place, leading to emergency surgical haemostasis. Emergency surgery may produce infection and organ damage.

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Purpose: The treatment of early miscarriage with medication is effective and low in side effects. Nevertheless, no uniform dosage regimen has yet been established, nor has it been possible to determine whether previous pregnancies and births with their respective modes of delivery play a role in the effectiveness of Misoprostol. This study aimed to find predictive parameters for successful treatment with Misoprostol in early miscarriage.

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A disturbance in the metabolism of homocysteine in both the mother and the fetus has been implicated in several placental vasculopathy-related disorders, including pregnancy loss. This study aimed to provide insights into the potential role of homocysteine, Vitamin B12, and folic acid in early pregnancy losses, with a specific focus on the Turkish population. The results of 93 pregnant women who experienced miscarriage between 5 and 14 gestational weeks and 93 healthy pregnant women at the same gestational weeks were compared.

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Predictors of successful expectant and medical management of miscarriage: A systematic review.

Acta Obstet Gynecol Scand

December 2024

Department of Metabolism, Digestion and Reproduction, Imperial College, London, UK.

Article Synopsis
  • 15.3% of pregnancies result in miscarriage, and various management options exist (expectant, medical, surgical), but individual patient factors complicate decision-making.
  • The systematic review analyzed data from multiple databases up to April 2023, focusing on defined predictors for successful miscarriage management while excluding low-quality studies.
  • Key findings suggest that demographics, ultrasound features, and biochemical markers influence management outcomes, with incomplete miscarriages showing a higher success rate for expectant or medical management, highlighting the need for more extensive and standardized research to aid in personalized patient care.
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Article Synopsis
  • The study aimed to evaluate the effectiveness of combining estriol valerate and progesterone in preventing intrauterine adhesions (IUA) in patients who suffered early missed abortions after dilation and curettage.
  • Data from 120 patients were analyzed; 70 received the treatment while 50 did not, with results showing a significantly better response to the treatment in preventing IUA.
  • Key risk factors for developing IUA included a history of multiple miscarriages, small endometrial volume, thin endometrial thickness, and the absence of preventive treatment.
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The migration, proliferation, and apoptosis of trophoblastic cells play a crucial role in ensuring the effective preservation of pregnancy at the maternal-fetal interface. Any deviations in the structure and function of these cells might potentially result in the development of numerous pregnancy-related disorders, including missed abortion (MA). This study involved the examination of () expression in missed abortion = 18) and normal early pregnancy ( = 18) villus.

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Interpregnancy interval following missed abortion and the risk for preterm birth.

Eur J Obstet Gynecol Reprod Biol

September 2024

Department of Obstetrics and Gynecology, Rambam Health Care Campus, Haifa, Israel; Bruce Rappaport Faculty of Medicine, Technion-Israel Institute of Technology, Haifa, Israel.

Objective: Short inter-pregnancy interval (IPI) of <18 months following a live birth, has been associated with adverse pregnancy outcome. This study aimed to evaluate whether a short IPI following a medically treated missed abortion (MA) poses similar perinatal risks in a subsequent pregnancy.

Study Design: The retrospective analysis included patients with history of an MA at up to 10 weeks of gestation, treated with misoprostol (pgE1) only, and with a documented subsequent live pregnancy (2010-2022).

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The Success of Mifepristone and Misoprostol in the Management of Early Pregnancy Loss at a Community Hospital: A Prospective Study.

J Obstet Gynaecol Can

September 2024

Department of Obstetrics and Gynaecology, University of Toronto, Toronto, ON; Department of Obstetrics and Gynecology, North York General Hospital, Toronto, ON.

Article Synopsis
  • This study aimed to assess how effective a treatment regimen is for managing early pregnancy loss (EPL) by measuring the expulsion rate of the gestational sac.
  • Out of 441 participants, 188 were eligible, and those who followed the treatment protocol saw a 93.3% success rate in complete expulsion of the gestational sac after 14 days.
  • The findings suggest that using mifepristone and misoprostol is a safe and effective option for managing EPL, although some participants were later diagnosed with retained products of conception.
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[Analysis of Prenatal Ultrasound Manifestations in 15 Cases of Cantrell Syndrome].

Sichuan Da Xue Xue Bao Yi Xue Ban

May 2024

( 610045) Department of Ultrasound, Sichuan Provincial Maternity and Child Health Care Hospital, Chengdu 610045, China.

Article Synopsis
  • Cantrell syndrome is a rare congenital disorder with defects in the midline abdominal wall, lower sternum, diaphragm, and an associated intracardiac defect.
  • This study analyzed 15 cases of fetuses diagnosed with Cantrell syndrome using prenatal ultrasound between March 2018 and July 2023, focusing on ultrasound findings and postnatal outcomes.
  • The research highlights the importance of thorough prenatal imaging for early detection and monitoring of Cantrell syndrome, which has been underrepresented in comprehensive studies.
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