accelerates methicillin-resistant eradication by promoting migration and activation of neutrophils.

Background: (Lanata) is generally used to treat pustule infection in Inner Mongolia folk medicine and is called "the holy medicine for pustule." However, the pharmacological mechanism of Lanata in treating pustule infection is still unclear.

Aims: This study aimed to investigate the therapeutic effects of Lanata on skin infection and explore the underlying mechanisms.

 (Acoraceae), a new species from Southern China.

(Acoraceae) is a commonly used seasoning in southern China. It was previously misidentified as (Yamam.) F.

Aspect category sentiment analysis based on pre-trained BiLSTM and syntax-aware graph attention network.

Aspect Category Sentiment Analysis (ACSA) is a fine-grained sentiment analysis task aimed at predicting the sentiment polarity associated with aspect categories within a sentence.Most existing ACSA methods are based on a given aspect category to locate sentiment words related to it. When irrelevant sentiment words have semantic meaning for the given aspect category, it may cause the problem that sentiment words cannot be matched with aspect categories.

Stabilization of [(N)BX] and [(N)BX] (X = H, F, Cl, Br) by Conjugation and Hyperconjugation Effects.

The isolation of nucleophilic boron bases has led to a paradigm shift in boron chemistry. Previous studies of the bis(carbene) borylene complexes revealed that these compounds possess strong donor abilities, and their reaction inertness is due to the large steric hindrance between boron reagents and reactant. In the present study, we have theoretically studied the [(N)BX] and [(N)BX] compounds (X = H, F, Cl, Br).

Chain-mediated effect of physical activity between Chinese language-based L2 motivational self-system and intended effort.

The L2 Motivational Self System (L2MSS) determines an individual's motivation in second language learning and influences the learning experience and intended effort. Although physical activity (PA) has been shown to enhance academic efficacy, the role of PA in whether it promotes second language learning efficacy has not been elucidated. Therefore, the present study examined PA as a mediator and explored its ameliorative effects in L2MSS.

Combined Impact of Canada Goldenrod Invasion and Soil Microplastic Contamination on Seed Germination and Root Development of Wheat: Evaluating the Legacy of Toxicity.

The concurrent environmental challenges of invasive species and soil microplastic contamination increasingly affect agricultural ecosystems, yet their combined effects remain underexplored. This study investigates the interactive impact of the legacy effects of Canada goldenrod ( L.) invasion and soil microplastic contamination on wheat ( L.

Subway opening enables urban green development: Evidence from difference-in-differences and double dual machine learning methods.

Urban rail transport is an important part of transport infrastructure, which is significant in empowering green-oriented urban development. However, few studies in the existing literature explore the effect of subway opening on urban green development. This paper uses Chinese data of 281 prefecture-level cities from 2008 to 2021 to explore the influence and mechanism of subway opening on urban green total factor productivity (GTFP) through the difference-in-differences (DID) and double dual machine learning (DDML) methods.

Linkage Mapping and Identification of Candidate Genes for Cold Tolerance in Rice (Oryza Sativa L.) at the Bud Bursting Stage.

Rice is highly sensitive to low temperatures, making cold stress a significant factor limiting its growth, especially during the bud bursting stage. To address this, an RIL population derived from a cross between cold-tolerant and cold-sensitive rice varieties was used to identify nine QTLs linked to cold tolerance under temperatures of 4 ℃, 5 °C, and 6 ℃ using a high-density genetic map. One candidate gene, LOC_Os07g44410, was identified through gene function annotation, haplotype analysis, and qRT-PCR, with two main haplotypes (Hap1 and Hap2) showing distinct phenotypic differences.

Association of sarcopenia with Parkinson's disease and related functional degeneration among older adults: A prospective cohort study in Europe.

Background: Former evidence on the risk factors for Parkinson's disease (PD), especially the PD-related functional limitation and neurological outcomes was scarce. We aimed to explore the association between sarcopenia and PD along with the PD-related functional degeneration. Further, we testified the heterogeneity in the above relationships of multimorbidity severity and patterns.

Impact of aerosol-photolysis interaction on the ozone concentration in the upper boundary layer on Mountain Everest.

Previous research has revealed that, during the late afternoon, the ozone (O3) concentration tends to elevate at the northern perimeter of Mount Everest (5200 m above sea level). This increase is attributed to the natural gradient of rising O3 concentration with height, exacerbated by the corresponding downstream mountain winds. Our recent field observations corroborate this finding, showing a consistent increase in O3 concentrations by approximately 13.

Urbanized lands degrade surrounding grasslands by deteriorating the interactions between plants and soil microbiome.

To mitigate overgrazing on grasslands, towns were constructed in some pastoral regions of China to relocate pastoralists. Nevertheless, whether and how the urbanized lands impact the surrounding grassland ecosystem remains unclear. We assessed the impacts of urbanized lands on the plant and soil interactions within the surrounding grasslands in order to ensure an eco-sustainable pastoralist relocation.

Tibetan-Chinese speech-to-speech translation based on discrete units.

Speech-to-speech translation (S2ST) has evolved from cascade systems which integrate Automatic Speech Recognition (ASR), Machine Translation (MT), and Text-to-Speech (TTS), to end-to-end models. This evolution has been driven by advancements in model performance and the expansion of cross-lingual speech datasets. Despite the paucity of research on Tibetan speech translation, this paper endeavors to tackle the challenge of Tibetan-to-Chinese direct speech-to-speech translation within the multi-task learning framework, employing self-supervised learning (SSL) and sequence-to-sequence model training.

Downregulation of collagen IV deposition and ITGB1-FAK signaling pathway to inhibit adipogenesis: A novel mechanism of swertiamarin in treating type 2 diabetes mellitus.

Extracellular matrix (ECM) and integrins are important biological macromolecules. ECM especially collagen IV (COLIV) deposition modulates the integrin-FAK signaling pathway involved in adipogenesis and is strongly associated with insulin resistance. Type 2 diabetes mellitus (T2DM) mice were given swertiamarin (STM) by intragastric administration.

A small underwater object detection model with enhanced feature extraction and fusion.

In the underwater domain, small object detection plays a crucial role in the protection, management, and monitoring of the environment and marine life. Advancements in deep learning have led to the development of many efficient detection techniques. However, the complexity of the underwater environment, limited information available from small objects, and constrained computational resources make small object detection challenging.

Effect of family support and work resources in the relationship of economic constraints and work volition: Evidence from China.

Background: As the pace of economic development slows, college students are facing an increasingly challenging employment landscape. For instance, the expansion of higher education has led to a swell in the number of job seekers, which has in turn intensified competition. Given the limited job opportunities, it's understandable that many college students are developing a pessimistic employment mindset.

Prevalence of congenital heart defects in people with Down syndrome: a systematic review and meta-analysis.

Background: The prevalence of congenital heart defects (CHD) in Down syndrome (DS) varies considerably across studies (from 16% to 84%). This study aimed to estimate the prevalence of CHD in people with DS (CHD-DS).

Methods: PubMed, Web of Science and the Chinese National Knowledge Infrastructure databases were searched through to 5 January 2023.

Epilepsy Prediction and Detection Using Attention-CssCDBN with Dual-Task Learning.

Epilepsy is a group of neurological disorders characterized by epileptic seizures, and it affects tens of millions of people worldwide. Currently, the most effective diagnostic method employs the monitoring of brain activity through electroencephalogram (EEG). However, it is critical to predict epileptic seizures in patients prior to their onset, allowing for the administration of preventive medications before the seizure occurs.

Traditional Knowledge and Efficacy Analysis of an Emerging Medicinal Food Plant: .

(Hua) Engl. ex K. Krause, locally known as (bitter greens) or , is a widely consumed wild vegetable and traditional herbal medicine in western Yunnan.

Sugemule-7 alleviates oxidative stress, neuroinflammation, and cell death, promoting synaptic plasticity recovery in mice with postpartum depression.

Postpartum depression (PPD) profoundly impacts the mental and physical health of women globally and is an incurable psychological disorder. Traditional pharmacological treatments often have strong side effects and may adversely affect infant health through breastfeeding, underscoring the critical need for natural and gentle treatment strategies. Sugemule-7, a traditional Chinese medicine comprising multiple natural plant ingredients, represents a potentially safer and more effective alternative.

Lightweight multidimensional feature enhancement algorithm LPS-YOLO for UAV remote sensing target detection.

Detecting small targets in UAV remote sensing images is challenging for traditional lightweight methods due to difficulty in feature extraction and high background interference. We propose LPS-YOLO, which improves small target feature extraction while reducing computational complexity by replacing the Conv backbone with SPDConv to retain fine-grained features. LPS-YOLO introduces the SKAPP module for better feature fusion and incorporates the E-BiFPN and OFTP structures to efficiently preserve and transfer backbone information.

Prospects for the development of medical professionalism education in the AI perspective: A qualitative study of Chinese postgraduate medical students' written reflections.

Introduction: Medical professionalism education is of paramount importance to the development of medical careers and medical students. Currently, there is a need for more research in China on the integration of artificial intelligence (AI) and medical professionalism education.

Methods: For this study, we collected 44 written reflections from first-year postgraduate students of clinical medicine in China during the spring semester of 2024 on the prospect of applying AI in conjunction with medical professionalism education.

Development of a PET Probe Targeting Bromodomain and Extra-Terminal Proteins for In Vitro and In Vivo Visualization.

Bromodomain and extra-terminal (BET) proteins are critical regulators of gene transcription, as they recognize acetylated lysine residues. The BD1 bromodomain of BRD4, a member of the BET family, has emerged as a promising therapeutic target for various diseases. This study aimed to develop and evaluate a novel C-11 labeled PET radiotracer, [C]YL10, for imaging the BD1 bromodomain of BRD4 in vivo.

Examining Family Atmosphere and School Climate Within Psychology of Working Theory Among Chinese Rural College Students.

The employment situation for college students has worsened due to the increase in the number of graduates and the impact of the COVID-19 pandemic on the economy. Consequently, the pressure to find employment has also increased, particularly for rural college students. Drawing on the Psychology of Working Theory (PWT), the present study was performed to examine the applicability of some proposed pathways in the PWT and test the relationships between family atmosphere and school climate and work volition, career adaptability, and future decent work perception within 946 rural college students (243 men and 703 women; Mage = 19.

Comprehensive metabolic profiling of three plants of Ardisia based on UPLC-QTOF-MS coupled with bioactivity assays.

Ethnopharmacological Relevance: Ardisia is a large genus of Primulaceae, 734 accepted species worldwide, and most species are used as ethnomedicines for the treatment of bruises, rheumatism, tuberculosis, and various inflammatory diseases. According to our previous ethnobotanical survey, Ardisia gigantifolia Stapf, Ardisia hanceana Mez (Da-luo-san), and Ardisia crenata Sims (Xiao-luo-san) are commonly used in folk medicine for the treatment of rheumatism. Among them, A.

Unveiling Schizophrenia: a study with generalized functional linear mixed model via the investigation of functional random effects.

Previous studies have identified attenuated pre-speech activity and speech sound suppression in individuals with Schizophrenia, with similar patterns observed in basic tasks entailing button-pressing to perceive a tone. However, it remains unclear whether these patterns are uniform across individuals or vary from person to person. Motivated by electroencephalographic (EEG) data from a Schizophrenia study, we develop a generalized functional linear mixed model (GFLMM) for repeated measurements by incorporating subject-specific functional random effects associated with multiple functional predictors.