4 results match your criteria: "Minneapolis Heart Institute Foundation and the Valve Science Center[Affiliation]"

Aims: Degenerative mitral stenosis (DMS) is due to degenerative mitral annular calcification (MAC) and valvular calcification. However, DMS impacts on the outcome, and therefore, potential treatment needs are poorly known. We aimed at evaluating survival after DMS diagnosis by Doppler echocardiography in routine practice.

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Background: Aortic-valve-stenosis (AS) is a frequent degenerative valvular-disease and carries dismal outcome under-medical-treatment. Transvalvular pressure gradient reflects severity of the valve-disease but is highly dependent on flow-conditions and on other valvular/aortic characteristics. Alternatively, aortic-valve-area (AVA) represents a measure of aortic-valve lesion severity conceptually essential and practically widely-recognized but exhibits multiple-limitations.

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Article Synopsis
  • The study tracked the incidence of severe aortic stenosis (AS) in Olmsted County, MN, from 1997 to 2016, finding a stable rate of approximately 52.5 cases per 100,000 patients per year despite an increasing overall number due to population growth.
  • Incidence trends revealed that while rates in men remained stable, there was a decline in women, indicating potential differences in disease presentation or diagnosis between genders.
  • Aortic valve replacement (AVR) procedures became more timely over the two decades, associated with improved survival rates, but overall mortality rates after treatment remained high, highlighting ongoing challenges in managing severe AS.
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Outpatient tricuspid regurgitation in the community: Clinical context and outcome.

Int J Cardiol

February 2024

Division of Cardiology, Department of Medicine, University of Verona, Verona, Italy. Electronic address:

Article Synopsis
  • The study aimed to assess the prevalence of tricuspid regurgitation (TR) in a specific community and its impact on patient outcomes like survival and hospitalization.
  • During a follow-up of 6.1 years, moderate or severe TR was found in 4.8% of 6,797 patients, showing varying event-free survival rates based on clinical context.
  • Patients with TR experienced decreased event-free survival, especially those with heart failure and significant left-sided valvular heart disease, indicating that TR is a significant health concern.
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