Catestatin-A Novel Predictor of Left Ventricular Remodeling After Acute Myocardial Infarction.

Catestatin was discovered as a potent inhibitor of catecholamine secretion and plays important roles in the cardiovascular system. Our previous study demonstrates a close relationship between catestatin levels and prognosis of ST-elevation myocardial infarction (STEMI). Using the same population, the goal of this study is to investigate the ability of catestatin to predict left ventricular (LV) remodeling in STEMI patients.

Correlation of plasma catestatin level and the prognosis of patients with acute myocardial infarction.

Catestatin is a peptide which is a potent inhibitor of catecholamine secretion and played essential functions in the cardiovascular system. Previous research found that dramatic changes of catestatin were associated with hemodynamics in acute myocardial infarction (AMI) during the first week after the AMI symptoms onset, but whether catestatin is also involved in the pathophysiological progression after AMI and then a predictor for outcomes is not clear. The aim of this study is to determine the correlation of plasma catestatin levels at different time points and the prognosis of AMI.

[The impact of regular exercise habit on exercise tolerance early after acute myocardial infarction].

Objective: To investigate the relationship between regular exercise habit and peak oxygen uptake (VO₂peak) early after acute ST-elevation myocardial infarction (STEMI).

Methods: A total of 239 patients who underwent cardiopulmonary exercise testing (CPET) early after STEMI in a single exercise laboratory were enrolled. Influencing factors to VO₂peak were analyzed retrospectively.

Growth differentiation factor 15 in cardiovascular diseases: from bench to bedside.

Context: Growth differentiation factor 15 (GDF-15) is a novel cytokine showing close association with cardiovascular diseases. The biological mechanism and clinical use of GDF-15 in cardiovascular diseases have been well demonstrated. We review recent investigations from both basic research and clinical trials into the biological role of GDF-15.