238 results match your criteria: "MingDao University[Affiliation]"

Background: In bronchiectasis, nontuberculous mycobacteria (NTM) lung disease (NTM-LD) is a well-known coexisting infection. However, microorganism coisolates and clinical NTM-LD predictors are poorly studied.

Methods: Patients with bronchiectasis diagnosed by means of computed tomography between January 2017 and June 2020 were screened, using the date of computed tomography as the index date.

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Vitamin D deficiency is common in patients with inflammatory bowel disease (IBD). In this study, we aimed to evaluate the prevalence and risk factors of vitamin D deficiency in a Taiwanese IBD cohort. Vitamin D levels were checked in adult patients with IBD who were treated at Changhua Christian Hospital, a medical center in central Taiwan, from January 2017 to December 2023.

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Effects of chilling and cryoprotectants on glycans in shrimp embryos.

Cryobiology

September 2024

National Museum of Marine Biology & Aquarium, Pingtung, Taiwan; Graduate Institute of Marine Biology, National Dong Hwa University, Pingtung, Taiwan. Electronic address:

Article Synopsis
  • * This study focused on how chilling and cryoprotective agents affect the glycan profiles of S. hispidus embryos at a specific developmental stage, finding mannose to be the most abundant glycan crucial for embryonic growth and signaling.
  • * Results indicated that chilling changed the levels of certain glycans and that DMSO, a cryoprotective agent, helps minimize cell damage during cold exposure, providing new insights into how glycans function in shrimp embryo resilience and growth.
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  • This study aimed to validate a simplified radiological scoring system for evaluating clinical symptoms and outcomes in Taiwanese patients with noncystic fibrosis bronchiectasis (NCFB).
  • It involved analyzing data from 2,753 patients, assessing their bronchiectasis type and severity using a modified Reiff score derived from high-resolution CT scans, and correlating these with clinical features such as lung function and hospitalization rates.
  • The findings indicated that as the severity of bronchiectasis increased, patients experienced worse symptoms and lung function, and identified factors like age and pneumonia as independent predictors of mortality, suggesting the scoring system's utility in clinical assessments.
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Due to the comprehensive hepatitis B virus vaccination program in Taiwan since 1986, the development of antiviral therapy for chronic hepatitis B and chronic hepatitis C infection and covered by National health insurance. Besides, the increased prevalence of nonalcoholic fatty liver disease (NAFLD) and currently, approved therapy for NAFLD remain developing. The etiology of liver-related diseases such as cirrhosis and hepatocellular carcinoma required reinterpretation.

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Lonicerae japonicae (L. japonicae) flos is a medical and food homology herb. This study investigated the phenolic acid and flavonoid contents in L.

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Waxy corn starch with 6-12 % moisture was degraded by gaseous hydrogen chloride (HCl) then characterized chromatographically and microscopically to investigate the relationship between moisture-resulting changes in unit chain properties of starch and its susceptibility to swelling. Starches with the highest degradation extents at different moisture content had recoveries of 76-83 % (w/w) and the weight-average degrees of polymerization of 66-93 anhydroglucose unit. Additionally, the HCl-degraded starches were still of birefringent granules but with internal cavity.

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Long-term PM exposure is associated with asthma prevalence and exhaled nitric oxide levels in children.

Pediatr Res

January 2024

Institute of Environmental and Occupational Health Sciences, College of Public Health, National Taiwan University, Taipei, Taiwan, ROC.

Background: Exhaled nitric oxide concentration (FENO) is a marker of airway inflammation. This study aimed to evaluate the association of air pollution exposure with FENO levels and asthma prevalence with respiratory symptoms in school children.

Methods: We analyzed 4736 school children who reside in six townships near industrial areas in central Taiwan.

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The prevalence of inflammatory bowel disease (IBD) has increased worldwide. The prevalence of metabolic dysfunction associated fatty liver disease (MAFLD) has also risen. However, there is limited research on the connection between MAFLD and IBD in the Asian population.

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Article Synopsis
  • Lung cancer is the leading cause of cancer death, with stage IIIa non-small cell lung cancer (NSCLC) being particularly controversial in terms of treatment strategies.
  • A study analyzing 4,232 patients in Taiwan found that patients with adenocarcinoma had the highest 5-year overall survival (OS) rate, particularly those with T1N2 heterogenicity.
  • Surgical intervention significantly improved survival rates, with segmentectomy and lobectomy showing the best outcomes, highlighting the importance of individualized and multimodal treatment approaches.
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Article Synopsis
  • Chronic obstructive pulmonary disease (COPD) is a significant global health issue, with around 70-80% of cases undiagnosed, leading to poorer health outcomes and lower quality of life for patients.
  • Early detection of COPD is essential, and while strategies have been developed over the past decade, identifying undiagnosed cases remains challenging.
  • The review provides an overview of current literature on various case-finding strategies and instruments recommended by health organizations, alongside a proposed flowchart to effectively identify individuals at risk for COPD.
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Background: Hyperkalemia is a common complication of chronic kidney disease (CKD). Hyperkalemia is associated with mortality, CKD progression, hospitalization, and high healthcare costs in patients with CKD. We developed a machine learning model to predict hyperkalemia in patients with advanced CKD at an outpatient clinic.

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Vitrification and ultrarapid laser warming are crucial for the cryopreservation of animal embryos, oocytes, and other cells of medicinal, genetic, and agricultural value. In the present study, we focused on alignment and bonding techniques for a special cryojig that combines a jig tool and jig holder into one piece. This novel cryojig was used to obtain a high laser accuracy of 95% and a successful rewarming rate of 62%.

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Background: Successful weaning from mechanical ventilation is important for patients admitted to intensive care units. However, models for predicting real-time weaning outcomes remain inadequate. Therefore, this study aimed to develop a machine-learning model for predicting successful extubation only using time-series ventilator-derived parameters with good accuracy.

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Background: The aim of this study is to assess the impact of the duration of the integrated disease management (IDM) program on COPD-related outcomes in real-world setting.

Methods: A retrospective cohort study among 3771 patients with COPD who had regularly completed 4 visits of IDM program within 1 year between April 1, 2017 and December 31, 2018. CAT score as the primary outcome used to investigate the association between IDM intervention duration and improvement in CAT score.

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Comparison of Machine Learning Models and the Fatty Liver Index in Predicting Lean Fatty Liver.

Diagnostics (Basel)

April 2023

Department of Internal Medicine, Division of Gastroenterology, Changhua Christian Hospital, Changhua 500, Taiwan.

The reported prevalence of non-alcoholic fatty liver disease in studies of lean individuals ranges from 7.6% to 19.3%.

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Because of incomplete recycling resource management and technology development, inorganic sludge and slag has been misused in Taiwan. The recycling of inorganic sludge and slag is a pressing crisis. Resource materials with a sustainable use value are misplaced and have a significant impact on society and the environment, which greatly reduces industrial competitiveness.

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Article Synopsis
  • The study investigates the role of micro-RNA (miR-146a) in promoting the properties of cancer stem cells (CSCs) in oral squamous cell carcinoma (OSCC), which contributes to treatment failure and tumor recurrence.
  • Findings reveal that miR-146a is overexpressed in OSCC and is linked to enhanced CSC characteristics, such as self-renewal and aggressive traits.
  • The research identifies Numb as a target of miR-146a; targeting this miRNA/Numb pathway could provide new therapeutic strategies for treating oral cancer.
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Individuals' engagement in sports and sport-related entertainment is reported to improve their subjective well-being (SWB). We investigated whether online video sport spectatorship (OVSS) enhances the SWB of college students and whether sport involvement moderates the correlation between OVSS and SWB. For this, a pretest-posttest experimental design with a 3-week-long intervention (OVSS) was adopted.

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The electronic medical record management systems may improve monitoring and control of disease activity in patients with ankylosing spondylitis.

Sci Rep

March 2023

Division of Allergy, Immunology, and Rheumatology, Department of Internal Medicine, Taichung Veterans General Hospital, No. 1650, Taiwan Boulevard Sect. 4, Taichung, 40705, Taiwan ROC.

To investigate the impact of an electronic medical record management system (EMRMS) on disease activity and the frequency of outpatient visits among patients with ankylosing spondylitis (AS). We identified 652 patients with AS who were followed up for at least 1 year before and after the first Ankylosing Spondylitis Disease Activity Score (ASDAS) assessment and compared the number of outpatient visits and average visit time within 1 year before and after the initial ASDAS assessment. Finally, we analyzed 201 patients with AS who had complete data and received ≥ 3 continuous ASDAS assessments at an interval of 3 months, and we compared the results of the second and third ASDAS assessments with those of the first.

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Serum globulin is a novel predictor of mortality in patients undergoing peritoneal dialysis.

Sci Rep

January 2023

Division of Nephrology, Department of Internal Medicine, Changhua Christian Hospital, 135 Nanxiao Street, Changhua City, 500, Taiwan.

Serum globulin, which is composed mainly of immunoglobulins and acute phase proteins, can be considered as reflecting the inflammatory state. We conducted the present study to investigate the role of globulin in mortality risk in patients undergoing peritoneal dialysis (PD). The study participants were categorized by the median globulin value (2.

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Background: Acute kidney injury (AKI) is associated with an increased incidence of poor liver graft and renal outcomes in patients who have undergone liver transplantation (LT). To date, no comprehensive study has compared patients with and without post-LT AKI and analyzed patients who recovered from AKI versus those who did not.

Methods: Patients who received living LT between January 2003 and January 2019 were enrolled.

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