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Effect of mannitol on brain metabolism and tissue oxygenation in severe haemorrhagic stroke.

J Neurol Neurosurg Psychiatry

April 2011

Division of Neurocritical Care, Department of Neurology, Columbia University Medical Center, Milstein Hospital 8-300 Center, New York, NY 10032, USA.

Background: The impact of osmotic therapies on brain metabolism has not been extensively studied in humans. The authors examined if mannitol treatment of raised intracranial pressure will result in an improvement in brain metabolism together with the expected drop in intracranial pressure (ICP).

Methods: This is a retrospective review of prospectively collected data.

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