292 results match your criteria: "Military hospital of Tunis.[Affiliation]"

Adenocarcinoma of the bladder is a rare histologic variant representing only 0.5-2 % of bladder cancer. We report the case of 83-year old male patient who consulted for gross hematuria evolving for one month.

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Colo-colonic intussusception secondary to giant colonic lipoma in an adult: A case report.

Int J Surg Case Rep

August 2024

General Surgery Department, Military Hospital of Tunis, Mont Fleury-1008, Tunis, Tunisia; Faculty of Medicine of Tunis, 15, Djebel Lakhdhar Street - 1007 Bab Saadoun, Tunis, Tunisia.

Introduction: Intestinal intussusception is a rare complication in adults, accounting for 1 % of intestinal obstructions. Unlike in children, it is often secondary to a malignant lesion, rarely a benign one. Colonic lipomas are asymptomatic benign tumors often discovered incidentally.

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Xanthogranulomatous cholecystitis: Diagnostic dilemma and surgical solution in geriatric patients: A case report.

Int J Surg Case Rep

July 2024

General Surgery Department, Military Hospital of Tunis, Mont Fleury-1008, Tunis, Tunisia; Faculty of Medicine of Tunis, 15, Djebel Lakhdhar Street - 1007 Bab Saadoun, Tunis, Tunisia.

Introduction: Xanthogranulomatous Cholecystitis (XGC) is a rare inflammatory condition characterized by the presence of xanthogranulomas within the gallbladder wall, often mimicking gallbladder carcinoma (GBC). Diagnosis is challenging and may require biopsy. Once GBC is excluded, an open cholecystectomy is recommended, although laparoscopic cholecystectomy is increasingly being performed with great caution.

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A replication study of sHLA-E influence on schizophrenia and bipolar disorder.

Encephale

May 2024

Translational Neuropsychiatry Laboratory, fédération hospitalo-universitaire de médecine de précision en psychiatrie (FHU ADAPT), DMU IMPACT, AP-HP, Paris Est Créteil University and Fondation FondaMental, Inserm U955 IMRB, 94010 Créteil, France.

Article Synopsis
  • The study investigates the link between soluble HLA-E isoforms and the risk and severity of schizophrenia and bipolar disorder in a Tunisian population.
  • Findings indicate that bipolar disorder patients have significantly higher levels of sHLA-E, especially during acute phases, while schizophrenia patients show higher levels in stable conditions but not generally.
  • The results support the idea that sHLA-E can be considered a reliable inflammatory marker for both disorders, confirming previous findings in a French cohort.
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Anaphylaxis triggered by a hidden threat: A rare hydatid disease case report.

Int J Surg Case Rep

June 2024

General Surgery Department, Military Hospital of Tunis, Mont Fleury-1008, Tunis, Tunisia; Faculty of Medicine of Tunis, 15, Djebel Lakhdhar Street - 1007 Bab Saadoun, Tunis, Tunisia.

Introduction And Importance: Hydatid disease, caused by Echinococcus granulosus, is a zoonotic infection prevalent in specific regions, including Tunisia. Complications are rare but potentially life-threatening. This case report highlights the significance of early diagnosis and intervention in a unique case where anaphylaxis resulted from minor abdominal trauma in a 17-year-old male with an undiagnosed hydatid cyst.

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Pulmonary alveolar proteinosis is a very rare diffuse lung disease characterized by the accumulation of amorphous and periodic acid Schiff-positive lipoproteinaceous material in the alveolar spaces due to impaired surfactant clearance by alveolar macrophages. Three main types were identified: Autoimmune, secondary and congenital. Pulmonary alveolar proteinosis has been previously reported to be associated with several systemic auto-immune diseases.

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A case report: Peritonitis secondary to perforated locally advanced gastrointestinal stromal tumor.

Int J Surg Case Rep

June 2024

General Surgery Department, Military Hospital of Tunis, Mont Fleury, 1008 Tunis, Tunisia; Faculty of Medicine of Tunis, 15, Djebel Lakhdhar Street, Bab Saadoun, 1007 Tunis, Tunisia.

Introduction And Importance: Gastrointestinal stromal tumors (GISTs) are rare mesenchymal neoplasms predominantly affecting the gastrointestinal tract. While they often remain asymptomatic, GISTs can lead to acute abdominal emergencies, such as peritonitis secondary to tumor perforation, a rare yet serious complication. Here, we present a unique case of a locally advanced ileal gastrointestinal stromal tumor complicated by generalized purulent peritonitis, emphasizing the diagnostic and management challenges associated with this condition.

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Doubly complicated: A case of massive non-parasitic liver cyst presenting with dyspnea and inferior vena cava compression: A rare case report.

Int J Surg Case Rep

June 2024

General Surgery Department, Military Hospital of Tunis, Mont Fleury, 1008 Tunis, Tunisia; Faculty of Medicine of Tunis, 15, Djebel Lakhdhar Street - 1007 Bab Saadoun, Tunis, Tunisia.

Introduction And Importance: Simple hepatic cysts, common benign liver conditions, are increasingly detected incidentally due to advancements in imaging technologies. While typically asymptomatic, complications such as compression of neighboring structures can arise, presenting unique diagnostic and management challenges. We present a doubly complicated case of a massive non-parasitic liver cyst in a 61-year-old female patient, manifesting with dyspnea and compression of the inferior vena cava.

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Objective: Early detection of cardiovascular diseases is based on accurate quantification of the left ventricle (LV) function parameters. In this paper, we propose a fully automatic framework for LV volume and mass quantification from 2D-cine MR images already segmented using U-Net.

Methods: The general framework consists of three main steps: Data preparation including automatic LV localization using a convolution neural network (CNN) and application of morphological operations to exclude papillary muscles from the LV cavity.

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Total small bowel volvulus on incomplete common mesentery, an exceptional complication in geriatric patients: A rare case report.

Int J Surg Case Rep

May 2024

General Surgery Department, Military Hospital of Tunis, Mont Fleury-1008, Tunis, Tunisia; Faculty of Medicine of Tunis, 15, Djebel Lakhdhar Street - 1007 Bab Saadoun, Tunis, Tunisia.

Introduction And Importance: The incomplete common mesentery, resulting from a rotational anomaly, is a rare but potentially life-threatening condition. This congenital anomaly is characterized by persistent embryonic bowel arrangement and an extremely short mesentery root. Complications typically manifest during neonatal or pediatric stages, with limited occurrences in adulthood.

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A rare case report: Huge ileal leiomyoma: Clinical presentation, management, and implications.

Int J Surg Case Rep

April 2024

General Surgery Department, Military Hospital of Tunis, Mont Fleury-1008, Tunis, Tunisia; Faculty of Medicine of Tunis, 15, Djebel Lakhdhar Street - 1007 Bab Saadoun, Tunis, Tunisia.

Introduction And Importance: Leiomyomas, commonly known as fibroids, are benign soft tissue tumors mostly found in the uterus. Although predominantly uterine, they can occur rarely in other areas, notably in the gastrointestinal tract. This article emphasizes an unusual case: an ileal leiomyoma in a 54-year-old patient, showcasing the distinct diagnostic and management challenges it presents.

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Humoral and cellular response of two different vaccines against SARS-CoV-2 in a group of healthcare workers: An observational study.

J Immunol Methods

May 2024

Research Unit UR17DN05, Military Hospital of Tunis, 1008 Montfleury, Tunis, Tunisia; University Tunis El Manar, Tunis, Tunisia; Department of Anesthesiology and Intensive Care, Military Hospital of Tunis, 1008 Montfleury, Tunis, Tunisia.

On March 13, 2021, Tunisia started a widespread immunization program against SARS-CoV-2 utilizing different vaccinations that had been given emergency approval. Herein, we followed prospectively a cohort of participant who received COVID-19 vaccine (Pfizer BioNTech and Sputnik-Gameleya V). The goal of this follow-up was to define the humoral and cellular immunological profile after immunization by assessing neutralizing antibodies and IFN- γ release.

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Introduction: Coronavirus disease 2019 (COVID-19) pandemic might have an unprecedented impact on dental education.

Aim: The main aim of this study was to investigate the impact of COVID-19 among Tunisian dental students.

Methods: This was a cross-sectional study carried out from January to March 2022, at the Faculty of Dental Medicine of Monastir (FDMM), Tunisia.

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Surgical perspective on perianal Bowen's disease: A rare case report.

Int J Surg Case Rep

April 2024

General Surgery Department, Military Hospital of Tunis, Mont Fleury-1008, Tunis, Tunisia; Faculty of Medicine of Tunis, 15, Djebel Lakhdhar Street - 1007 Bab Saadoun, Tunis, Tunisia.

Introduction And Importance: Bowen's Disease (BD) stands out as a dermatologic entity known for its rarity and diagnostic intricacies. While BD is recognized for its diverse clinical presentations, its occurrence in the perianal region is particularly exceptional. Our case contributes to the limited body of knowledge regarding perianal BD, shedding light on its distinctive characteristics and guiding clinicians in navigating the intricacies associated with this uncommon presentation.

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Diagnostic consideration of lipoma-like lesion: A case report of primary cutaneous Rosai-Dorfman disease.

Int J Surg Case Rep

April 2024

General Surgery Department, Military Hospital of Tunis, Mont Fleury-1008, Tunis, Tunisia; Faculty of Medicine of Tunis, 15, Djebel Lakhdhar Street - 1007 Bab Saadoun, Tunis, Tunisia.

Introduction And Importance: Rosai-Dorfman disease (RDD) is a rare disorder characterized by benign histiocytic proliferation. The purely cutaneous variant of Rosai-Dorfman disease is exceptionally uncommon. This abstract centers on an extraordinary case-an instance of primary cutaneous Rosai-Dorfman disease (PCRDD), a rare cutaneous variant within an already infrequent disorder.

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Introduction: Cerebral palsy (CP) is a group of permanent disorders of the development of movement and posture causing activity limitation.

Aim: To evaluate the epidemiological, clinical, and radiological profile of children with CP and to study the therapeutic modalities in daily clinical practice.

Method: This was a retrospective, descriptive study, carried out in a physical medicine and rehabilitation department, including all the patients referred with the diagnosis of cerebral palsy between January 2000 and December 2016.

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Prevalence of chronic kidney disease in Tunisian diabetics: the TUN-CKDD survey.

BMC Nephrol

February 2024

Tunisian Association of Nephrology, Dialysis, and Transplantation, Tunis, Tunisia.

Article Synopsis
  • - The prevalence of diabetes in Tunisia rose significantly from 15.5% in 2016 to 23% in 2023, with a corresponding study examining chronic kidney disease (CKD) among diabetic patients to understand its prevalence based on factors like specialist type and demographic characteristics.
  • - An observational study conducted between January and February 2023 included over 10,000 diabetic patients, using KDIGO guidelines to diagnose CKD, focusing on data collected across various healthcare settings in Tunisia.
  • - The results indicated that 38.7% of diabetic patients had CKD, with higher rates among males and older patients, as well as those diagnosed by nephrologists. CKD was more prevalent in the Mid-East region of Tunisia
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Genetic testing for hereditary cancer syndromes in Tunisian patients: Impact on health system.

Transl Oncol

May 2024

Laboratory of Biomedical Genomics and Oncogenetics, LR20IPT05, Institut Pasteur de Tunis, University of Tunis El Manar, Tunis, Tunisia; Laboratory of Human and Experimental Pathology, Institut Pasteur de Tunis, Tunis, Tunisia. Electronic address:

Article Synopsis
  • - This study focuses on the challenges of cancer management in Africa, particularly in Tunisia, where limited resources and health system issues affect cancer care and the need for better identification of hereditary cancer syndromes.
  • - Researchers analyzed clinicopathological data from 521 patients and performed genetic testing, identifying 36 BRCA mutations associated with hereditary breast and ovarian cancer syndrome, along with other rare syndromes like Li-Fraumeni and Bloom syndrome.
  • - The findings emphasize the importance of enhancing genetic education and implementing genetic screening programs in Tunisia and other African countries to improve cancer management and reduce hereditary disease burdens.
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[Not Available].

Tunis Med

June 2023

Department of Cardiology, Military hospital of Tunis, Faculty of Medicine of Tunis, University of Tunis El Manar, Tunisia.

Introduction: The conventional radial approach (CRA), the gold standard approach for percutaneous coronary interventions (PCI), is associated with the risk of radial artery occlusion (RAO). The distal radial approach (DRA) is an effective alternative with fewer complications.

Aim: To evaluate the efficacy in terms of puncture success and safety by RAO rate of the DRA in elective PCI in Tunisian patients.

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Recent advances in sequencing technologies have significantly increased our capability to acquire large amounts of genetic data. However, the clinical relevance of the generated data continues to be challenging particularly with the identification of Variants of Uncertain Significance (VUSs) whose pathogenicity remains unclear. In the current report, we aim to evaluate the clinical relevance and the pathogenicity of VUSs in DNA repair genes among Tunisian breast cancer families.

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Methemoglobinemia is due to oxidization of divalent ferro-iron of hemoglobin to ferri-iron of methemoglobin (MetHb) which is incapable of transferring oxygen to tissues. This disease may be acquired by intoxication with oxidizing agents or inherited with a mutation of CYB5R3, the gene coding for the methemoglobin reductase or cytochrome B5 reductase 3 responsible for the reduction of MetHb to hemoglobin. We report the case of 2 sisters aged respectively of 15 and 8 months.

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A rare case report: Gallbladder-associated ectopic liver tissue: Challenges, insights, and surgical considerations.

Int J Surg Case Rep

February 2024

General Surgery Department, Military Hospital of Tunis, Mont Fleury-1008, Tunis, Tunisia; Faculty of Medicine of Tunis, 15, Djebel Lakhdhar Street - 1007 Bab Saadoun, Tunis, Tunisia.

Introduction And Importance: Ectopic liver tissue (ELT), a rare anomaly distinct from accessory liver, challenges conventional embryonic morphogenesis. Unlike the latter, ELT lacks a connection to the main liver, showcasing an unusual growth of normal liver tissue beyond its customary location. This peculiarity poses clinical and radiological challenges for surgeons throughout their careers, particularly during laparoscopic or open procedures.

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