1,941 results match your criteria: "Military Institute of Medicine[Affiliation]"
Exp Appl Acarol
December 2024
Department of Eco-Epidemiology of Parasitic Diseases, Institute of Developmental Biology and Biomedical Sciences, Faculty of Biology, University of Warsaw, 1 Miecznikowa Street, 02-096, Warsaw, Poland.
Ixodes ricinus tick is a vector of bacteria of Borreliella genus and Borrelia miyamotoi. Exposure to ticks constitutes occupational risk to soldiers, but the current knowledge on this subject is still limited. Therefore, the aim of this study was to evaluate tick abundance and prevalence of infection with Borreliella spp.
View Article and Find Full Text PDFJ Clin Med
November 2024
Department of Hematology, Military Institute of Medicine-National Research Institute, Szaserow Street 128, 04-141 Warsaw, Poland.
: The purpose of this study was to analyze the behaviors of inflammatory markers, such as procalcitonin and C-reactive protein (CRP), during treatment with obinotuzumab (an anti-CD20 antibody). : Our non-randomized observational study prospectively evaluated a cohort of 22 adult patients with lymphoproliferative neoplasms, chronic lymphocytic leukemia (CLL), and follicular lymphoma (FL) with indications for obinotuzumab therapy. : All patients had their blood drawn to determine blood counts, CRP, and procalcitonin, as well as body temperature measurements and blood cultures performed for bacterial infections on day 0 before administration of the anti-CD20 antibody.
View Article and Find Full Text PDFJ Clin Med
November 2024
Department of Otolaryngology, Military Institute of Medicine-National Research Institute, 04-349 Warsaw, Poland.
Disruptions in lacrimal function can lead to various conditions, including chronic nasolacrimal duct obstruction and dacryocystitis, which may cause symptoms like excessive tearing, pain, and recurrent infections. In cases where pharmacological treatments are insufficient, surgical intervention becomes essential, which is widely used to restore effective tear drainage. This study evaluated postoperative outcomes of laser-assisted dacryocystorhinostomy (LDCR) in 48 patients, totaling 56 treated eyes, over a follow-up period of 6 months to 3.
View Article and Find Full Text PDFJ Clin Med
November 2024
Cardiothoracic Centre, Freeman Hospital, Newcastle-upon-Tyne NE7 7DN, UK.
Recent randomized clinical trials (RCTs) of STEMI patients with multi-vessel disease (MVD) reported potential superiority of immediate (ICR) vs. staged complete revascularization (SCR). Inherently, the risk of procedural MI is less likely to be detected in ICR patients, and this may have influenced the results.
View Article and Find Full Text PDFMol Ther
December 2024
Translational Vectorology Research Unit, Children's Medical Research Institute, Faculty of Medicine and Health, The University of Sydney, Westmead, Australia; Australian Genome Therapeutics Centre, Children's Medical Research Institute and Sydney Children's Hospitals Network, Westmead, NSW 2145, Australia; Laboratory of Molecular Oncology and Innovative Therapies, Military Institute of Medicine - National Research Institute, Warsaw, Poland. Electronic address:
Chimeric antigen receptor (CAR) T-cell (CAR-T) therapies present options for patients diagnosed with certain leukemias. Recent advances of the technology included a method to integrate the CAR into the T-cell receptor alpha constant (TRAC) locus to take advantage of the endogenous promoter and regulatory elements for CAR expression. This method used adeno-associated viral (AAV) vectors based on AAV6 to deliver the donor template encoding the CAR construct.
View Article and Find Full Text PDFOtolaryngol Pol
December 2024
Department of Otolaryngology, Regional Specialist Hospital Wroclaw, Research & Development Centre, Wroclaw, Poland, Faculty of Medicine, Wroclaw University of Science and Technology, Wroclaw, Poland, Institute of Human Genetics, Polish Academy of Sciences, Poznan, Poland.
<b>Introduction:</b> Head and neck cancer (HNC) incidence and mortality have increased significantly among the elderly in Poland over the last two decades. This trend reflects the challenges of an aging population and underscores the need for specialized cancer care for seniors.<b>Aim:</b> The study aimed to analyze the morbidity and mortality of HNC among the elderly (ages 60-69, 70-79, and 80+) in Poland between 1999 and 2021, and predict trends until 2035, emphasizing the dynamics in the 80+ age group.
View Article and Find Full Text PDFFront Endocrinol (Lausanne)
December 2024
Chair and Department of Endocrinology, Jagiellonian University Medical College, Krakow, Poland.
Lancet Gastroenterol Hepatol
December 2024
Department of Gastroenterology and Digestive Endoscopy, IRCCS Hospital San Raffaele, Milan, Italy; Vita-Salute San Raffaele University, Milan, Italy.
Background: There is a need for efficacious therapies for patients with Crohn's disease that are better tolerated and more durable than available treatments. We aimed to evaluate the efficacy and safety of filgotinib, an oral Janus kinase 1 preferential inhibitor, for treating Crohn's disease.
Methods: This phase 3, double-blind, randomised, placebo-controlled trial was conducted in 371 centres in 39 countries.
Exp Ther Med
January 2025
Department of Dermatology, Military Institute of Medicine-National Research Institute, Central Clinical Hospital Ministry of Defense, 04-141 Warsaw, Poland.
Egypt Heart J
December 2024
Department of Interventional Cardiology and Internal Diseases, Military Institute of Medicine - National Research Institute, Zegrzyńska 8 Street, 05-119, Legionowo, Poland.
Front Immunol
December 2024
Department of Internal Diseases, Nephrology and Dialysis, Military Institute of Medicine-National Research Institute, Warsaw, Poland.
Cryoglobulinemia is a rare disease characterized by the presence of cryoglobulins in the blood serum. It is usually caused by autoimmune, lymphoproliferative, or infectious factors. The pathogenesis of cryoglobulinemia is not well understood, therefore, genetic testing is very important.
View Article and Find Full Text PDFFront Endocrinol (Lausanne)
December 2024
Department of Pediatric Surgery, Institute of Pediatrics, Jagiellonian University Medical College, Krakow, Poland.
Otolaryngol Pol
November 2024
Department of Otolaryngology and Laryngological Oncology with Clinical Department of Craniofacial Surgery, Military Institute of Medicine - National Research Institute, Warsaw, Poland.
<b>Introduction:</b> In its assumptions, rhinoplasty is intended to improve the aesthetics and restore normal function of the nose. In the Polish literature, a new tool has recently emerged for simultaneous assessment of the impact of rhinoseptoplasty on the external appearance and functionality of the nose.<b>Aim:</b> The aim of this study consisted in the surveying of patients having undergone rhinoplasty procedures using a validated and translated Standardized Cosmesis and Health Nasal Outcomes Survey (SCHNOS) questionnaire and the Rhinoplasty Outcome Evaluation (ROE) questionnaire to assess the functional and aesthetic outcomes of rhinoplasty.
View Article and Find Full Text PDFPathogens
November 2024
Department of Epidemiology and Tropical Medicine, Military Institute of Medicine-National Research Institute, 04-141 Warsaw, Poland.
Pathogens
October 2024
Department of Epidemiology and Tropical Medicine, Military Institute of Medicine-National Research Institute, 04-141 Warsaw, Poland.
Madagascar is one of the poorest countries in the world. The country's extreme weather conditions, poor sanitation, and weak economy facilitate the spread of parasitic diseases. Infections with intestinal parasites are particularly dangerous for children because they can cause malnutrition and anemia, which, in turn, have a negative effect on children's cognitive functions and physical development.
View Article and Find Full Text PDFInt J Mol Sci
November 2024
Faculty of Chemistry, Jagiellonian University, Gronostajowa 2, 30-387 Krakow, Poland.
Therap Adv Gastroenterol
November 2024
Szymon Drygała Takeda Pharma Sp. z.o.o., St. Prosta 68, Warsaw, Mazovia Province 00-838, Poland.
Background: The Crohn's Disease (CD) Activity Index (CDAI), Inflammatory Bowel Disease (IBD) Questionnaire (IBDQ), and IBD-Fatigue (IBD-F) scale are useful patient-reported outcome (PRO) tools for assessing the treatment benefits of vedolizumab (VDZ) beyond clinical trial endpoints in patients with CD.
Objectives: To assess clinical response, clinical remission, steroid-free remission, changes from baseline for PROs, and safety in a real-world cohort of patients with moderate-to-severe active CD treated with VDZ.
Design: POLONEZ II was a multicenter, observational, prospective study across 10 Polish centers from April 2020 to October 2023 for 54 weeks in patients with CD eligible for reimbursed VDZ.
Med Sci Monit
November 2024
Department of Cardiology and Internal Medicine, Military Institute of Medicine - National Research Institute, Warsaw, Poland.
BACKGROUND Due to the chronic effects of excess growth hormone (GH) and insulin-like growth factor-1 (IGF-1), patients with acromegaly (AC) may develop acromegalic cardiomyopathy with biventricular hypertrophy, systolic and diastolic dysfunction, resulting in congestive heart failure. This study aimed to evaluate the echocardiographic parameters of left ventricular (LV) diastolic function and impedance cardiography (ICG) parameters of cardiovascular hemodynamics in patients with AC. MATERIAL AND METHODS A total of 33 patients (male to female ratio: 1.
View Article and Find Full Text PDFDermatol Ther (Heidelb)
December 2024
Department of Dermatology, Institute of Medical Sciences, Medical College of the University of Rzeszów, Rzeszów, Poland.
Otolaryngol Pol
November 2024
Department of Otolaryngology and Laryngological Oncology with Clinical Department of Craniofacial Surgery, Military Institute of Medicine - National Research Institute, Warsaw, Poland.
Sci Rep
November 2024
Department of Paediatrics, Paediatric Nephrology and Allergology, Military Institute of Medicine - National Research Institute, 128 Szaserow Str, 04-141, Warsaw, Poland.
Joint Bone Spine
November 2024
Rheumatology Unit, Department of Medical Sciences, Surgery and Neurosciences Department of Medical Sciences, Surgery and Neurosciences, University of Siena and Azienda Ospedaliero-Universitaria Senese [European Reference Network (ERN) for Rare Immunodeficiency, Autoinflammatory, and Autoimmune Diseases (RITA) Center], Siena, Italy. Electronic address:
J Rheumatol
November 2024
Luca Cantarini, Department of Medical Sciences, Surgery and Neurosciences, Research Center of Systemic Autoinflammatory Diseases and Behçet's Disease Clinic, University of Siena, Siena, Italy; Azienda Ospedaliero-Universitaria Senese [European Reference Network (ERN) for Rare Immunodeficiency, Autoinflammatory and Autoimmune Diseases (RITA) Center] Siena, Italy.
Stem Cell Res Ther
November 2024
Institute of Biophysics, HUN-REN Biological Research Centre, Szeged, 6726, Hungary.
Background: One of the most severe consequences of ageing is cognitive decline, which is associated with dysfunction of the brain microvasculature. Thus, repairing the brain vasculature could result in healthier brain function.
Methods: To better understand the potential beneficial effect of endothelial progenitor cells (EPCs) in vascular repair, we studied the adhesion and integration of EPCs using the early embryonic mouse aorta-gonad-mesonephros - MAgEC 10.
Chest
November 2024
Department of Cardiac and Vascular Diseases, John Paul II Hospital, Krakow, Poland; Pulmonary Circulation Centre, Department of Cardiac and Vascular Diseases, Krakow, Poland. Electronic address: